FABIAN DAVAMANI AMALRAJ



Salutation
Associate Professor Dr

School/Centre
School of Health Sciences

Department
Applied Biomedical Science and Biotechnology

Position
Associate Professor

Email
fabian_davamani@imu.edu.my

Professional Network


Education

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Ph.D (Microbiology), 2000 University of Madras, Institute of Basic Medical Sciences
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M.Sc. (Life Science), 1993 University of Madras
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B.Sc. (Life science), 1991 University of Madras

Research Funding
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Evaluation of the role of inflammatory protein biomarkers LAMA2, MLL4 and PLXDC2 as a predictor for diabetes IMU Internal Research Grant | 07 Jan 2025 - 04 Jul 2025
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Antimicrobial and anti-biofilm effect of gold nanoparticles against oral inflammation and infection. IMU Internal Research Grant | 11 Jul 2024 - 31 Jul 2025
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Correlation between gene mutations and dietary pattern in different ethnic groups among early-onset colorectal carcinoma patients under 40 years: a systematic review IMU Internal Research Grant | 04 Jun 2024 - 30 Sep 2024
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Virulence assessment of Staphylococcus aureus isolated from diabetic foot ulcers IMU Internal Research Grant | 03 Jun 2024 - 30 Sep 2024
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Analysis of gut microbiome in people who have undergone appendectomy IMU Internal Research Grant | 03 Jun 2024 - 31 Dec 2024
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Bioactive and Antibacterial Entanglement Wave Function of Graphene Quantum Carbon Dots on Enamel Substrate: An In-Vitro Study IMU Internal Research Grant | 01 Apr 2024 - 31 Dec 2024
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Effect of gold nanoparticles on candida albicans adhesion and initial biofilm formation IMU Internal Research Grant | 01 Apr 2024 - 30 Apr 2025
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Exploration of the use of generative artificial intelligence (AI) by undergraduate students in health professions programmes and their perspectives on AI use IMU Internal Research Grant | 04 Sep 2023 - 31 Dec 2024
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Molecular Characterization of Methicillin-Resistant Staphylococcus aureus (MRSA) Strains Isolated from Diabetic Foot Ulcers (DFU): Insights into Antibiotic Resistance and Virulence IMU Internal Research Grant | 01 Sep 2023 - 30 Jun 2024
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Analysis of perception about basic concepts, pedagogy and construction of microlearning contents among the faculty and students in medical and health sciences IMU Internal Research Grant | 30 Jun 2023 - 31 Jul 2024
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Study of antibacterial effect of microcurrent stimulation on bacteria isolated from diabetic foot ulcers IMU Internal Research Grant | 01 Jun 2023 - 31 Dec 2023
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Stability Enhancement in Collagen Matrix: Comprehensive modification technologies of a Universal based Adhesive System for Understanding the Protein Structure IMU Internal Research Grant | 31 May 2023 - 31 May 2024
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Comparison of Osteogenic differentiation between 3D clumps of human periodontal ligament MSC and those in Scaffolds. PhD in Medical & Health Sciences (by Research) | 15 Jun 2021 - 15 Dec 2021
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Antibacterial Efficacy of propolis and wood vinegar against Staphylococcus aureus bacteria isolated from DFU Bachelor of Science (Hons) in Biomedical Science | 01 Jun 2021 - 31 Dec 2021
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Development and evaluation of an educational tool for microbiology skills training using augmented reality/virtual reality applications. IMU Internal Research Grants | 01 Jun 2021 - 31 Dec 2022
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Western blot analysis of signaling pathways modulated by lactoferricin B peptide in MDA-MB-231 breast cancer cell line Bachelor of Science (Hons) in Biomedical Science | 01 Jun 2021 - 31 Dec 2021
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PREVALENCE OF STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA ACROSS CHIROPRACTIC TABLE SURFACE IN AN IMU CHIROPRACTIC CLINIC SETTING Bachelor of Science (Hons) in Chiropractic | 21 Oct 2020 - 30 Sep 2021
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Synergy between Malaysian propolis and wood vinegar against Staphylococcus aureus, Pseudomonas aeruginosa Candida albicans and Escherichia coli IMU | 01 Jul 2020 - 01 Dec 2020
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Efficacy of lactoferricin B on triple negative breast cancer cell lines IMU | 01 Jul 2020 - 01 Dec 2020
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Synergistic effect between chlorhexidine and silver nanoparticles with activation techniques against Enterococcus faecalis – An in vitro study IMU | 01 May 2020 - 01 Dec 2021
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Analysis of mitochondrial membrane transition pore forming ability by Sideroflexin proteins SFXN4 and SFXN5 using live cell imaging studies IMU | 01 Sep 2019 - 01 Mar 2020
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Pro-carcinogenic effect of sitagliptin on pancreatic cancer cell lines IMU | 01 Jul 2019 - 01 Dec 2019
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Genome-Wide Sequence Analysis of Antartic Soil Bacteria and Validation of Biofilm and Heavy Metal Resistance Genes IMU | 01 Jul 2019 - 01 Dec 2019
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Effect of nanosilver, nanopropolis and their combination on the proliferation and expression of growth factor regulatory proteins and receptors in periodontal ligament stem cells IMU | 01 May 2019 - 01 May 2020
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Correlation of salivary cotinine and IgA levels in smokers with periodontitis – A clinical study IMU | 19 Apr 2019 - 01 Apr 2020
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Efficacy of a Silane-based Antimicrobial in Endodontic Infections IMU | 01 Apr 2019 - 01 Apr 2020
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Comparison of apical extrusion of intracanal bacteria and dentinal crack formation among various glide systems: IMU | 01 Mar 2019 - 01 Mar 2020
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In silico and in vitro antibacterial evaluation of Schiff base ligands and their metal complexes IMU Internal Research Grant | 05 Sep 2018 - 12 May 2021
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Synergistic effect of Malaysian propolis and antibiotics against biofilms formed by Enterococus faecalis,Staphylococcus epidermidis, S.aureus and Pseudomonas aeruginosa IMU | 01 Jul 2018 - 01 May 2020
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Iron oxide (IO) nanoparticles activity against Enterococcus faecalis, Staphylococcus epidermidis and candida albicans biofilms IMU | 01 Jul 2018 - 01 Feb 2019
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Characterization of Antibiotic Resistance in Bacterial Biofilms Associated with Diabetic Foot Ulcers and their Cytopathic Effect on Fibroblast Cell Line In vitro IMU | 01 Jul 2018 - 01 Dec 2018
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Oxidative stress in microbes following propolis treatments in Enterococcus faecalis, Staphylococcus epidermidis and candida albicans IMU | 01 Jul 2018 - 01 Feb 2019
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The Antimicrobial Efficacy of Gold Nanoparticles Suspension against Enterococcus faecalis and Candida albicans IMU | 18 Jun 2018 - 19 Feb 2019
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Antimicrobial efficacy, mechanism of action and biocompatibility of α-Mangostin nanoemulsion as an Endodontic irrigant PhD in Medical & Health Sciences | 01 May 2018 - 01 Dec 2022
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Antimicrobial Properties if Nanosilver, Nanopropolis and their Combination against Oral Microorganisms And Its Effect on Proliferation and VEGF Expression in Periodontol Ligament Cells IMU | 01 Mar 2018 - 01 Oct 2018
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Does sun exposure affect PTH response to serum Vitamin D in Malaysian adults? Fundamental Research Grant Scheme (FRGS) | 01 Jan 2015 - 01 Jan 2017
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Biomarkers of polar and lower latitudes microbes in relation to heavy metal stress. Flagship Program FP1213E036 diversity and adaptation of microbes: a cross latitudinal study MOSTI Flagship | 01 Aug 2014 - 31 Jul 2017
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Evaluation of the mechanism of lactoferricin B peptide in the inhibition of breast cancer FRGS | 30 Jul 2014 - 30 Jun 2017
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Post-Translational Regulation of Glutamine Metabolism by Acetylases and Deacetylases in Cancer Cells under Hypoxic Conditions FRGS | 01 May 2014 - 28 Oct 2016
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Effect of Madecassoside in Reducing Oxidative Stress and Blood Glucose and In Protecting The β-Cells in Streptozotocin-Nicotinamide Induced Diabetes in Rats FRGS | 01 Jan 2014 - 01 Dec 2017
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Development of Novel Chitosan-flavonoids(Propolis Ethanolic Extract) Nanoformulations Against Enterococcus faecalis in the Root Canal Using Extracted Human Tooth Model ERGS | 01 Jul 2013 - 31 Dec 2015

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Publications

Research Articles

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Antibacterial Efficacy of Graphene Nanoparticles against Enterococcus faecalis: In Vitro Study EUROPEAN JOURNAL OF DENTISTRY 2024
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A 3-D interactive microbiology laboratory via virtual reality for enhancing practical skills SCIENTIFIC REPORTS 2024
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A Novel Coated Suture Displays Antimicrobial Activity without Compromising Structural Properties JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY 2024
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Periodontitis and lipopolysaccharides: How far have we understood? EXPLORATION OF IMMUNOLOGY 2024
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Protective effects of madecassoside, a triterpenoid from Centella asiatica, against oxidative stress in INS-1E cells NATURAL PRODUCT RESEARCH 2024
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Effect of madecassoside in reducing oxidative stress and blood glucose in streptozotocin–nicotinamide-induced diabetes in rats JOURNAL OF PHARMACY AND PHARMACOLOGY 2023
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FIRST REPORT ON GASTROINTESTINAL PARASITE (GIP) INFECTION AMONG GERIATRIC COMMUNITY WITH COGNITIVE IMPAIRMENT IN SELANGOR, MALAYSIA MALAYSIAN JOURNAL OF PUBLIC HEALTH MEDICINE 2023
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Formulation and Characterization of a Novel Palm-Oil-Based α-Mangostin Nano-Emulsion (PO-AMNE) as an Antimicrobial Endodontic Irrigant: An In Vitro Study PROCESSES 2023
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Determining the Efficacy of Albendazole Against STH Infection Among Orang Asli MALAYSIAN JOURNAL OF MEDICINE AND HEALTH SCIENCES 2023
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Anticancer chiral and racemic ternary copper (II) complexes: Multiple mechanisms and epigenetic histone methyltransferase enzymes as novel targets POLYHEDRON 2022
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The potential of α-mangostin from garcinia mangostana as an effective antimicrobial agent—a systematic review and meta-analysis ANTIBIOTICS 2022
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Comparison of Apical Extrusion of Bacteria After Glide Path Preparation Between Manual K File, One G Rotary, and WaveOne Gold Glider Reciprocation Preparations EUROPEAN ENDODONTIC JOURNAL 2021
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3D clumps/extracellular matrix complexes of periodontal ligament stem cells ameliorate the attenuating effects of LPS on proliferation and osteogenic potential JOURNAL OF PERSONALIZED MEDICINE 2021
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Quaternary ammonium silane (k21) based intracanal medicament triggers biofilm destruction BMC ORAL HEALTH 2021
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Efficacy of incorporating silver nanoparticles into maxillofacial silicone against Staphylococcus aureus, Candida albicans, and polymicrobial biofilms THE JOURNAL OF PROSTHETIC DENTISTRY 2021
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Inhibition of breast cancer xenografts in a mouse model and the induction of apoptosis in multiple breast cancer cell lines by lactoferricin B peptide JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2021
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Effect of propolis nanoparticles against Enterococcus faecalis biofilm in the root canal Molecules 2021
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Knowledge, awareness, and practice (KAP) level of parasite infection among adults in Selangor, Malaysia INTERNATIONAL JOURNAL OF RESEARCH IN PHARMACEUTICAL SCIENCES 2021
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Comparison of apical extrusion of bacteria between Manual, One G rotary, and WaveOne Gold Glider reciprocation glide path files EUROPEAN ENDODONTIC JOURNAL 2021
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The mechanism of Bacteroides fragilis toxin contributes to colon cancer formation The Malaysian journal of medical sciences: MJMS 2020
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Effectiveness of chitosan-propolis nanoparticle against Enterococcus faecalis biofilms in the root canal BMC Oral Health 2020
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Establishing a technique for isolation and characterization of human periodontal ligament derived mesenchymal stem cells The Saudi Dental Journal 2020
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Effectiveness of chitosan-propolis nanoparticle against Enterococcus faecalis biofilms in the root canal BMC ORAL HEALTH 2020
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In vitro evaluation of octenidine as an antimicrobial agent against Staphylococcus epidermidis in disinfecting the root canal system Restorative dentistry & endodontics 2019
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Effect of root canal debridement on inflammatory cytokine levels Australian Endodontic Journal 2019
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Enantiomeric pairs of ternary copper (ii) complexes and their aldol-type condensation products: synthesis, characterization, and anticancer and epigenetic properties Dalton Transactions 2019
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Detection of Ascaris lumbricoides and Trichuris trichiura in various soil types from from an indigenous village in Malaysia Tropical Biomedicine 2019
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Comparing the antimicrobial efficacy of pediocin with chlorhexidine and calcium hydroxide as intracanal medicaments against persistent root canal infections Journal of conservative dentistry: JCD 2019
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Cationic chitosan-propolis nanoparticles alter the zeta potential of S. epidermidis, inhibit biofilm formation by modulating gene expression and exhibit synergism with antibiotics PloS one 2019
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Root canal irrigants influence the hydrophobicity and adherence of Staphylococcus epidermidis to root canal dentin: an in vitro study Restorative Dentistry & Endodontics 2018
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Chitosan-propolis nanoparticle formulation demonstrates anti-bacterial activity against Enterococcus faecalis biofilms PloS one 2017
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Factors associated with intestinal parasite infections in a resettled indigenous community in Malaysia International J Trop Dis Health 2016
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Molecular approach to detect Albendazole resistance in Trichuris trichiura among Orang Asli in Malaysia International Journal of Infectious Diseases 2016
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The effects of Malaysian propolis and Brazilian red propolis on connective tissue fibroblasts in the wound healing process BMC complementary and alternative medicine 2015
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The role of propolis in inflammation and orofacial pain: a review Annual Research & Review in Biology 2014
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Antifungal effectiveness of various intracanal medicaments against Candida albicans: an ex-vivo study BMC oral health 2014
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Bioactive molecules: current trends in discovery, synthesis, delivery and testing IeJSME 2013
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Cell surface heparan sulfates mediate internalization of the PWWP/HATH domain of HDGF via macropinocytosis to fine-tune cell signalling processes involved in fibroblast cell migration Biochemical Journal 2011
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Functional interaction between Envoncogene from Jaagsiekte sheep retrovirus and tumor suppressor Sprouty2 RETROVIROLOGY 2010
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Structures of two elapid snake venom metalloproteases with distinct activities highlight the disulfide patterns in the D domain of ADAMalysin family proteins Journal of structural biology 2010
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Association analysis of monoamine oxidase A gene and bipolar affective disorder in Han Chinese Behavioral and Brain Functions 2008
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Studies on the pathogenicity of Acanthamoeba isolated from cases of keratitis. Biomedicine 2000
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Studies of the prevalence of acanthamoeba keratitis in and around Chennai Indian Journal of Medical Microbiology 1998

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Other Publications

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Exploiting temperature and nutritional conditions for Poly microbial biofilm formation from Antarctic soil samples 8th Malaysian International Seminar on Antarctica -Polar regions in the Global Climate System | 18 Jun 2019
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Madecassoside protects pancreatic beta cells from glucotoxicity and oxidative stress BRITISH JOURNAL OF PHARMACOLOGY | 01 Jan 2019
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Chitosan-propolis nanoformulation for combating Enterococcus faecalis biofilms in vitro 8th World Medical nanotechnology congress and Expo | 08 Jun 2016
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Post-translational regulation of glutamine metabolism by acetylases and deacetylases in breast cancer cells under hypoxic conditions INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE | 01 Jan 2016


Supervisions
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Dr Siddharth | Master (Mixed Mode) | 30 Aug 2023 Thesis: Molecular Characterization of Methicillin-Resistant Staphylococcus aureus (MRSA) Strains Isolated from Diabetic Foot Ulcers (DFU): Insights into Antibiotic Resistance and Virulence
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SPOORTHI RAVI BANAVAR | Doctorate | 26 Dec 2019 - 04 Nov 2023 Thesis: ISOLATION AND CHARACTERIZATION OF PERIODONTAL LIGAMENT STEM CELLS TO ASSESS THE EFFECTS OF LPS AND HIGH GLUCOSE ON 3D CLUMPS OF PERIODONTAL CELLS AND THEIR POTENTIAL IN SCAFFOLD-FREE OSTEOGENIC DIFFERENTIATION
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Catherine Chong Sze Ling | Undergraduate | 01 Jun 2019 - 30 Dec 2022 Thesis: Resistance of multispecies biofilms from bacteria isolated from DFU against disinfectants and antibiotics
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Omer Sultan Sheriff | Doctorate | 02 May 2018 - 08 May 2023 Thesis: FORMULATION AND CHARACTERIZATION OF A NOVEL PALM-OIL-BASED α-MANGOSTIN NANOEMULSION (PO-AMNE) AS AN ANTIMICROBIAL ENDODONTIC IRRIGANT: AN IN-VITRO STUDY
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AMY CHONG SIEW PENG | Doctorate | 29 Aug 2016 - 21 Jan 2022 Thesis: POST-TRANSLATIONAL MODIFICATIONS OF PROTEINS INVOLVED IN GLUTAMINE METABOLISM BY ACETYLASES AND DEACETYLASES IN BREAST CANCER CELL LINES UNDER HYPOXIA
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MUHAMMAD RIZDWAN BIN MOHD ABD RAHMAN | Master (Research) | 12 Apr 2016 - 14 Dec 2021 Thesis: EVALUATION OF THE MECHANISM OF ACTION OF LACTOFERRICIN B PEPTIDE IN THE INHIBITION OF BREAST CANCER
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Ong Teik Hwa | Doctorate | 04 Aug 2014 - 08 Jun 2018 Thesis: Development of chitosan-propolis nanoparticle formulation as an antibacterial agent for control of biofilms formed by Enterococcus faecalis and Staphylococcus epidermidis
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Mehru Nisha | Doctorate | 03 Nov 2010 - 30 Dec 2014 Thesis: Soil Helminth
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Peter Asaga Mac | Doctorate | 02 Nov 2009 - 15 Nov 2014 Thesis: Toxoplasma gondii MIC8 GENE AS DNA AND CRUDE PROTEIN VACCINES AGAINST TOXOPLASMOSIS IN A MOUSE MODEL

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