CHAN KOK KEONG
Salutation
Dr
School/Centre
School of Medicine
Department
Human Biology
Position
Senior Lecturer
Email
Education
a
PhD (Cancer biology), 2012
International Medical University
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Master of Science (Natural products), 2004
Universiti Putra Malaysia
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Bachelor of Science (Hons.) (Biochemistry and Microbiology), 1995
Universiti Pertanian Malaysia
Research Funding
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Identification and functional validation of novel metastasis suppressor genes in nasopharyngeal carcinoma (NPC)
FRGS | 01 Sep 2022 - 31 Aug 2025
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Development of pooling strategy for COVID 19 RT-PCR testing
IMU | 17 Apr 2020 - 30 Apr 2020
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Investigating the Mechanism of Sorafenib-Induced Cardiotoxicity in Human Cardiomyocytes
IMU | 01 Jul 2019 - 01 Oct 2019
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Deconvoluting the molecular mechanisms of kinase induced cardiotoxicity
FRGS | 01 Nov 2018 - 31 Oct 2021
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Rapid identification of new molecular targets for treatment of endometrial cancer.
FRGS | 01 May 2013 - 30 Apr 2014
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Development of epidermal growth factor (EGF)-based cancer vaccine for cancer therapy
Bioven Sdn Bhd | 01 Nov 2011 - 01 May 2018
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Effects and Mechanism of action of Bacillus thuringiensis (Bt 18) parasporal inclusions on leukaemic cell lines (CCRF-SB, CCRF-HSB-2 and CEM-SS) and normal T-lymphocytes
International Medical University | 05 Dec 2004 - 30 Apr 2012
a
Effects of tocotrienols on cell viability and apoptosis in normal murine liver cells (BNL CL.2) and liver cancer cells (BNL 1ME A.7R.1), in vitro.
Hovid Sdn Bhd | 01 May 2001 - 31 May 2004
Publications
Research Articles
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Arthrobacter alpinus BP31 from Antarctic Soil Reveals Antibiotic Resistance and Resistance to Heavy Metals
-OENLG-(TM)SHOE -(TM)^OESHOE...' 2022
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COVID-19 Sample Pooling: From RNA Extraction to Quantitative Real-time RT-PCR
BIO-PROTOCOL 2021
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Influence of heavy metals on the occurrence of Antarctic soil microalgae
ANTARCTIC SCIENCE 2021
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A novel strategy for community screening of SARS-CoV-2 (COVID-19): Sample pooling method
PloS one 2020
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Phosphoinositide‐dependent Kinase‐1 (PDPK1) regulates serum/glucocorticoid‐regulated Kinase 3 (SGK3) for prostate cancer cell survival
Journal of cellular and molecular medicine 2020
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Bacillus thuringiensis parasporal proteins induce cell-cycle arrest and caspase-dependant apoptotic cell death in leukemic cells
Journal of Environmental Pathology, Toxicology and Oncology 2012
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Selective cytotoxic activity against leukemic cell lines from mosquitocidal Bacillus thuringiensis parasporal inclusions
Southeast Asian journal of tropical medicine and public health 2008
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Development of a purification method of pure primary lymphocytes for cell viability assays
THE MALAYSIAN JOURNAL OF MEDICAL SCIENCES: MJMS 2007
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Malaysian mosquitocidal soil bacterium (Bacillus thuringiensis) strains with selective hemolytic and lectin activity against human and rat erythrocytes
Southeast Asian journal of tropical medicine and public health 2006
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Effects of tocotrienols on cell viability and apoptosis in normal murine liver cells (BNL CL. 2) and liver cancer cells (BNL 1ME A. 7R. 1), in vitro
Asia Pacific Journal of Clinical Nutrition 2005
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Effects of tocotrienols on cell viability and apoptosis in normal murine liver cells (BNL CL. 2) and liver cancer cells (BNL 1ME A. 7R. 1), in vitro
ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION 2005
Other Publications
a
The Efficacy of Non-mosquitocidal Malaysian Bacillus thuringiensis Isolates Bt 18) Against Three Leukemic Cell Lines (CEM-SS, CCRF-SB and CCRF-HSB-2) and Its Mode of Cell Death
Thirteenth Asian Symposium on Medicinal Plants, Spices and other Natural Products (ASOMPS XIII) | 03 Nov 2008
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Quality Management System (QMS) to Reduce Centrifuge Usage Failure
IMU Q-Convention | 29 Aug 2007
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The Effects of Parasporal Inclusions From Malaysian Strains of Bacillus Thuringiensis on Leukaemic Cell Lines
International Medical and Health Congress | 25 May 2007
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Molecular and Immunological Analysis of a Bacillus thuringiensis isolate with Specific Activity Against Leukemic Cell Lines
2nd ASEAN Congress of Tropical Medicine and Parasitology | 21 May 2006
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Effects of tocotrienols on cell viability and apoptosis in normal murine liver cells (BNL CL. 2) and liver cancer cells (BNL 1ME A. 7R. 1), in vitro
International Palm Oil Congress | 24 Aug 2003
Supervisions
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Ng Zhi Win | Doctorate | 01 Sep 2023
Thesis: Development of Epidermal Growth Factor (EGF)- based Cancer Vaccine for Cancer Therapy
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Lee Wai Ching | Undergraduate | 01 Jul 2019 - 01 Nov 2019
Thesis: The Role of CACNA1D and CTNNA2 in the Molecular Pathway Responsible for Sorafenib -Induced Cardiotoxicity in Human Cardiomyocytes
a
Lee Xiao Xiang | Undergraduate | 01 Jul 2019 - 01 Nov 2019
Thesis: Expression Alteration of Genes in Insulin Secretion Pathway May Contribute to Sorafenib Induced Cardiotoxicity
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Michella Ong Wei Min | Undergraduate | 01 Jul 2019 - 01 Nov 2019
Thesis: Association of Axon Guidance Pathway Genes With Sorafenib-Induced Cardiotoxicity in Human Cardiomyocytes
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Tan Giah Pea | Undergraduate | 01 Jul 2019 - 01 Nov 2019
Thesis: Molecular Mechanism of Cardiac Toxicity BY Sorafenib in Human Cardiomyocytes
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Chong Qiao Xuan | Undergraduate | 01 Jun 2017 - 31 Oct 2017
Thesis: Functional Roles of P53 Mutants in The Regulation of Histone Modification in The ASPC-1 Pancreatic Cancer Cell Line
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Kyvern Ng | Undergraduate | 01 Jun 2017 - 31 Oct 2017
Thesis: Functional Roles of p53 Mutation Regulating PI3K Signaling in the ASPC-1 Pancreatic Cancer Cell Line
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Fu Mei Sim | Undergraduate | 01 Jun 2017 - 31 Oct 2017
Thesis: Functional Roles of p53 Mutation in Regulating The Cell Cycle in The AsPC-1 Pancreatic Cancer Cell Line
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Angel Ng Ann Jhee | Undergraduate | 01 Jun 2017 - 31 Oct 2017
Thesis: Functional Roles of Amyloid Precursor Protein as Signaling Molecule in The Regulation of Cell Cycle in Alzheimer's Disease
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Lau Xin Qi | Undergraduate | 01 Jun 2017 - 31 Oct 2017
Thesis: Functional Roles of Amyloid Precursor Protein as Signaling Molecule in The Regulation of Phosphoinositide 3Kinase Signaling Pathway in Alzheimer's Disease
a
Dorrie Elvera Ngui Xin Yee | Undergraduate | 01 Jun 2017 - 31 Oct 2017
Thesis: Functional Roles of p53 Mutation in The Regulation of Epithelial-Mesenchymal Transition in Pancreatic Cancer Cell Line
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Thian Lee Ping | Undergraduate | 01 Jun 2017 - 31 Oct 2017
Thesis: Functional Roles of Amyloid Precursor Protein as Signaling Molecule in The Regulation of Cell Adhesion and P53 Signaling Pathway in Alzheimer's Disease
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Chia Chun Hou | Undergraduate | 01 Jun 2017 - 31 Oct 2017
Thesis: Functional Roles of Amyloid Precursor Protein as Signaling Molecule in Histone Modification of Alzheimer's Disease
a
Eng Chin Khai | Undergraduate | 01 Jun 2016 - 01 Oct 2016
Thesis: Isolation and Identification of Bacteriophage Candidates From Malaysian Soil Against Multiple-Drug Resistant Bacteria (Clinical Isolates of Staphylococcus sp., Corynebacterium sp.)
a
Poo Mun Kit | Undergraduate | 01 Jun 2016 - 01 Oct 2016
Thesis: Isolation and Identification of Bacteriophage Candidates From Mossy Forest Soil Against Multiple-Drug Resistant Bacteria (Clinical Isolates of Staphylococcus sp., Corynebacterium sp.)
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Leong Kah Wai | Undergraduate | 01 Jun 2016 - 01 Oct 2016
Thesis: Isolation and Identification of Bacteriophage Candidates From Serendah Soil Against Multiple-Drug Resistant Bacteria (Clinical Isolates of Staphylococcus sp., Corynebacterium sp.)
a
Lim Wei Meng | Doctorate | 01 May 2013 - 31 May 2019
Thesis: Rapid identification of new molecular targets for treatment of endometrial cancer.