TAN BOON KEAT
Salutation
Dr
School/Centre
School of Medicine
Department
Biochemistry
Appointment
Head, Research Lab & Support Services
Position
Senior Lecturer
Email
Education
a
Doctor of Philosophy (PhD) (Medical and Health Sciences (Toxicology)), 2014
International Medical University
a
Master of Sciences (Drug Discovery), 2006
Universiti Putra Malaysia
a
Bachelor of Sciences (Biotechnology), 2000
Universiti Putra Malaysia
Memberships
a
Malaysia Board Of Technologists (MBOT)
Professional Technologist (Ts.)
2024 - Present
a
Malaysia Board Of Technologists (MBOT)
Graduate Technologist
2023 - Present
Research Funding
a
Molecular mechanism of β-hydroxybutyrate-induced cytotoxicity and apoptosis in cancer cell line
IMU Internal Research Grant | 01 Jul 2024 - 30 Jun 2025
a
Mechanism of nanoplastic-induced toxicity in a neuronal cell line
Bachelor in Medical Sciences | 30 Jan 2023 - 31 Jul 2023
a
Influence of polyethylene micro- and nano plastic on the
combined toxicity of copper and lead in Antarctic microalgae based on a suite of biomarkers and transcriptomic profiles
IMU Internal Research Grant | 02 Jan 2023 - 31 Dec 2025
a
Immunomodulatory effects of tiger milk mushroom extract Lignosus rhinocerus TM02® Cultivar (Agaricomycetes) in sensitized human keratinocyte cell line NCTC2544
BMedSc | 02 Jan 2023 - 30 Jul 2023
a
Immunomodulatory effects of Chinese Caterpillar Mushroom, Ophiocordyceps sinensis Cultivar OCS02 (Ascomycetes) in sensitized human keratinocyte cell line NCTC2544
Master in Molecular Medicine | 01 Sep 2022 - 31 Jul 2023
a
Identification of effective drug combinations targeting tumor-intrinsic immune resistance to cytotoxic T-cell (CTL)-mediated cytotoxicity in pancreatic cancer
Pharmacy | 28 Feb 2022 - 28 Feb 2023
a
Influence of polyethylene micro- and nano plastic on the combined toxicity of copper and lead in Antarctic microalgae based on a suite of biomarkers and transcriptomic profiles
YPASM | 01 Dec 2021 - 30 Nov 2024
a
Ecotoxicolgical Joint Effects of Nanoplastic and Herbicide Atrazine on Microalgae: Physiological and Molecular Responses
FRGS | 07 Sep 2021 - 06 Sep 2024
a
Isolation and characterisation of microalgae from selected pollution sites of rivers in Malaysia
IMU | 01 Dec 2020 - 30 May 2021
a
Molecular mechanisms of toxicity induced by nanoplastics in human cells
MoHE Fundamental Research Grant Scheme (FRGS) | 01 Nov 2020 - 31 Oct 2023
a
Toxicity of triclosan in tropical and Antarctic isolate of Chlorella: non-monotonic response
IMU | 01 Nov 2020 - 01 Mar 2021
a
Development of pooling strategy for COVID 19 RT-PCR testing
IMU | 17 Apr 2020 - 30 Apr 2020
a
Isolation and characterisation of microalgae from a garbage dumping site
IMU | 01 Dec 2019 - 01 May 2020
a
Isolation and characterisation of microalgae from a hot springs in Malaysia
Medical Biotechnology | 01 Jan 2017 - 01 Jan 2018
a
Response of Microalgae to Repeated Exposure to Glufosinate Ammonium at Different Temperatures
FRGS | 01 Aug 2016 - 31 Jan 2020
a
Comparative study of different Pteropine orthreovirus in nasopharyngeal cell lines
Medical Biotechnology | 01 Jan 2016 - 01 Jan 2017
a
Airborne Cyanobacteria as Potential Producers of Useful Pigments
Medical Biotechnology | 01 Jan 2016 - 01 Jan 2017
a
Comparative study of different Pteropine Orthreoviruses in different cell line and mice
IMU | 01 Jul 2015 - 30 Jun 2016
a
Assessment of the combined effects of nutrient enrichment and pesticide toxicity on various biomarker in microalgae
FRGS | 01 Jan 2015 - 01 Jan 2017
a
Influence of salinity on the toxicity of single-walled carbon nanotubes in marine microalgae
Medical Biotechnology | 02 Jan 2014 - 30 Apr 2014
Publications
Research Articles
a
Neurotoxicity of nanoplastics: A review
F1000RESEARCH 2024
a
Human cytokeratin 1 plays a role in the interaction of Pteropine orthoreovirus with Hek293 cells but not HeLa cells
MICROBES AND INFECTION 2023
a
Pteropine Orthoreovirus, PRV7S (Sikamat Virus) Demonstrates Oncolysis in Nasopharyngeal Carcinoma Cell Lines
FRONTIERS IN BIOSCIENCE-LANDMARK 2022
a
Impact of microplastics and nanoplastics on human health
NANOMATERIALS 2021
a
COVID-19 Sample Pooling: From RNA Extraction to Quantitative Real-time RT-PCR
BIO-PROTOCOL 2021
a
A novel strategy for community screening of SARS-CoV-2 (COVID-19): Sample pooling method
PLOS ONE 2020
a
Sensitivity of selected tropical microalgae isolated from a farmland and a eutrophic lake to atrazine and endosulfan
JOURNAL OF APPLIED PHYCOLOGY 2019
a
Combined effects of glufosinate ammonium and temperature on the growth, photosynthetic pigment content and oxidative stress response of Chlorella sp. and Pseudokirchneriella subcapitata
JOURNAL OF APPLIED PHYCOLOGY 2018
a
Crystal structure and functional analysis of human C1ORF123
PEERJ 2018
Supervisions
a
Aw Yong Poi Yi | Doctorate | 01 Jan 2024
Thesis: Influence of polyethylene micro- and nano plastic on the combined toxicity of copper and lead in Antarctic microalgae based on a suite of biomarkers and transcriptomic profiles
a
Wong Ming Hui | Undergraduate | 30 Jan 2023 - 31 Jul 2023
Thesis: Mechanism of nanoplastic-induced toxicity in a neuronal cell line
a
Lam Chuo Z | Undergraduate | 02 Jan 2023 - 30 Jul 2023
Thesis: Immunomodulatory effects of tiger milk mushroom extract Lignosus rhinocerus TM02® Cultivar (Agaricomycetes) in sensitized human keratinocyte cell line NCTC2544
a
YONG YI KENG | Master (Mixed Mode) | 01 Sep 2022 - 31 Jul 2023
Thesis: Immunomodulatory effects of Chinese Caterpillar Mushroom, Ophiocordyceps sinensis Cultivar OCS02 (Ascomycetes) in sensitized human keratinocyte cell line NCTC2544
a
CHEONG KA SENG | Undergraduate | 28 Feb 2022 - 28 Feb 2023
Thesis: EFFECT OF A CYCLIN-DEPENDENT KINASES (CDK) INHIBITOR, ABEMACICLIB AND ITS COMBINATION WITH CHEMOTHERAPY IN TARGETING PARENTAL AND CTL- RESISTANT PDAC CELLS
a
NGAN WAN LI | Undergraduate | 28 Feb 2022 - 28 Feb 2023
Thesis: THE EFFECTS OF RIBOCICLIB AND ITS COMBINATION WITH CHEMOTHERAPY IN PANCREATIC CANCER HARBOURING TUMOUR-INTRINSIC IMMUNE RESISTANCE TO CYTOTOXIC T-CELLS
a
Ong Sze Ji | Undergraduate | 28 Feb 2022 - 28 Feb 2023
Thesis: Effect of a cyclin dependent kinase inhibitor, alvocidib and its combination with chemotherapy in targeting parental and cytotoxicTcells resistant pancreatic cancer cells
a
TAN NIAN WAN | Undergraduate | 28 Feb 2022 - 28 Feb 2023
Thesis: EFFECTS OF AT7519 AND ITS COMBINATION WITH GEMCITABINE IN PANCREATIC CANCER HARBOURING TUMOUR-INTRINSIC IMMUNE RESISTANCE TO CYTOTOXIC T-CELLS
a
HONG YAN HAN | Undergraduate | 28 Feb 2022 - 28 Feb 2023
Thesis: EFFECTS OF MILCICLIB (PHA-848125) AND ITS COMBINATION WITH CHEMOTHERAPY IN PANCREATIC CANCER HARBOURING TUMOUR-INTRINSIC IMMUNE RESISTANCE TO CYTOTOXIC T-CELLS
a
FRANCIS TEE HE LONG | Undergraduate | 28 Feb 2022 - 28 Feb 2023
Thesis: Effects of dinaciclib and its combination with chemotherapy in pancreatic cancer harbouring tumor-intrinsic immune resistance to cytotoxic t-cells
a
GIAM MUN NING | Undergraduate | 28 Feb 2022 - 28 Feb 2023
Thesis: THE EFFECTS OF TRILACICLIB (G1T28) AND ITS COMBINATION WITH CHEMOTHERAPY IN PANCREATIC CANCER HARBOURING TUMOUR- INTRINSIC IMMUNE RESISTANCE TO CYTOTOXIC T-CELLS
a
AZRAAI DANIAL | Undergraduate | 01 Dec 2020 - 31 May 2021
Thesis: ISOLATION AND CHARACTERISATION OF MICROALGAE FROM THE BOHOL RIVER
a
BRYAN SOONG CHOR YUE | Undergraduate | 01 Dec 2020 - 30 May 2021
Thesis: Isolation and Characterisation of Microalgae from Kuyoh River
a
LOW QIN HAO | Undergraduate | 01 Nov 2020 - 01 Mar 2021
Thesis: TOXICITY OF TRICLOSAN IN PSEUDOKIRCHNERIELLA SUBCAPITATA: NONMONOTONIC RESPONSE
a
Dorea Soong Shi Hui | Doctorate | 01 Nov 2020 - 31 Oct 2023
Thesis: Molecular mechanisms of toxicity induced by nanoplastics in human cells
a
Yong Kai John | Undergraduate | 01 Dec 2019 - 01 May 2020
Thesis: Isolation and characterisation of microalgae from a garbage dumping site
a
Fong Kar Hoe | Undergraduate | 01 Sep 2016 - 31 Mar 2017
Thesis: COMPARATIVE STUDY OF DIFFERENT PTEROPINE ORTHREOVIRUS IN NASOPHARYNGEAL CELL LINES
a
PHUA HONG YUEH | Undergraduate | 01 Sep 2016 - 31 Mar 2017
Thesis: COMPARATIVE STUDY OF DIFFERENT PTEROPINE ORTHOREOVIRUS IN NASOPHARYGEAL CELL LINES
a
LIEW ZHEN WEN | Undergraduate | 01 Sep 2016 - 31 Mar 2017
Thesis: COMPARATIVE STUDY OF PULAU STRAIN OF Pteropine Orthoreovirus IN DIFFERENT NASOPHARYNGEAL CELL LINES.
a
Reuben A/L Parama Iswara | Undergraduate | 01 Jul 2015 - 30 Jun 2016
Thesis: Comparative study of different Pteropine Orthreoviruses in different cell line and mice