WONG SIEW TUNG



Salutation
Dr

School/Centre
School of Medicine

Department
Microbiology and Immunology

Position
Senior Lecturer




Education

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PhD (Molecular Parasitology), 2013 International Medical University
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M Sc (Molecular Biology), 2006 Universiti Putra Malaysia
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BSc (Hons) (Biomedical Science), 2001 Universiti Putra Malaysia

Research Funding
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Studies to investigate mechanisms of protective effect of Atorvastatin against NMDA-induced Excitotoxic Retinal Injury in Rats: Role of Autophagy IMU Internal Research Grant | 05 Sep 2024 - 30 Jun 2027
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Anticancer effects of Gamma-Tocotrienol Against Breast Cancer: A systematic Review IMU Internal Research Grant | 01 Jun 2024 - 31 Dec 2024
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Anticancer effects of Spirulina: A systematic Review IMU Internal Research Grant | 01 Jun 2024 - 31 Dec 2024
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Determination of oncolytic activity of Pteropine orthoreovirus in killing acute myeloid leukemia IMU Internal Research Grant | 01 Jan 2024 - 30 Jun 2024
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Exploring the potential role of estrogen in reducing neuroinflammatory changes in collagen induced rheumatoid arthritis rat model. IMU Internal Research Grant | 01 Jul 2023 - 31 Dec 2023
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Role of sphingolipid rheostat in the neuroprotective effect of atorvastatin against NMDA-induced excitotoxic retinal injury IMU Internal Research Grant | 01 Apr 2023 - 31 Mar 2026
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Molecular mechanisms of toxicity induced by polyfluoroalkyl substances in human bronchial and alveolar epithelial cells FRGS | 07 Sep 2021 - 06 Sep 2023
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Molecular mechanisms of toxicity induced by nanoplastics in human cells FRGS | 01 Nov 2020 - 31 Oct 2022
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Investigating the effect of Epithelial Growth Factor Receptor (EGFR) in Pteropine orthoreovirus (PRV) in killing Nasopahryngeal Carcinoma (NPC) cells. IMU | 01 Aug 2020 - 01 Dec 2020
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Development of pooling strategy for COVID 19 RT-PCR testing IMU | 17 Apr 2020 - 30 Apr 2020
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Assessment of medically important human pathogen prevalent on surfaces of the Outpatient Health Clinics in Selangor IMU | 01 Feb 2020 - 01 Jul 2020
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Single nucleotide polymorphisms (SNPs) of SLC2A2 (GLUT2) gene and risk of prediabetes and type-2 diabetes mellitus among Malaysian Indians in Seremban District: a pilot study IMU | 01 Feb 2020 - 01 Jul 2020
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An alternative nitric oxide-based strategy in protecting against experimental cerebral malaria FRGS 2019-1 | 01 Oct 2019 - 30 Sep 2024
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Molecular characterization of echoviruses from Hospital Batu Pahat IMU | 01 Oct 2019 - 01 Dec 2019
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Development of an Optical Biosensor for the Detection of Plasmodium berghei - Phase II IMU | 01 Sep 2019 - 01 Feb 2020
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Mechanisms of DDT and permethrin resistance in Aedes albopictus collected from Bukit Jalil and Kepong, Malaysia IMU | 01 Aug 2019 - 01 Dec 2020
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Histopathological changes seen in Syrian golden hamster (Mesocricetus auratus) in response to Plasmodium berghei infection IMU | 01 Aug 2019 - 01 Jun 2020
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Comparative study of different strains of Pteropine orthreoviruses in a mouse model IMU | 01 Jul 2019 - 01 Sep 2019
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Determine the optimal viral titer load of Pteropine orthreoviruses in killing nasopharyngeal carcinoma cell lines IMU | 01 Jun 2019 - 01 Sep 2019
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Indoor air quality (IAQ) of two type 1 community clinics at Selangor IMU | 19 Mar 2019 - 01 Feb 2020
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Seroprevalance of Pteropine Orthoreovirus and Mammalian Orthoreovirus in Swine Sera in Peninsular Malaysia IMU | 01 Mar 2019 - 01 Dec 2019
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The role of cytokines (interluekin and tumour necrosis factors) and the gene-gene interaction in Helicobacter pylori infected gastric cancer: A hospital based case-control study FRGS | 01 Jan 2019 - 27 Dec 2021
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Investigating the Effect of Orientin (Flavone) and Madecassoside (Triterpenoid) on Saffold Virus Infection in SH-SY5Y (Neuroblastoma) and BV2 (Microgial) Cells IMU | 01 Mar 2018 - 01 Feb 2019
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Serological Assays for Screening of Pteropine Orthoreovirus Infection IMU | 01 Mar 2018 - 01 Dec 2018
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Development of an Optical Biosensor for the Detection of Trypanosoma evansi / Plasmodium berghei IMU | 01 Mar 2018 - 01 Dec 2018
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System biology comparison between mice with single and co-infection from Toxoplasma gondii and/or Trypanosoma evansi FRGS | 01 Dec 2015 - 31 May 2018

Publications

Research Articles

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Cytokine levels in the severity of falciparum malaria: An umbrella review ACTA TROPICA 2024
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Prevalence of zoonotic (brugian) filariasis in Asia: A proportional meta-analysis ACTA TROPICA 2023
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Facilitators and barriers to engaging communities in health service research on dengue control in Indo-Pacific region: a systematic review BMC PUBLIC HEALTH 2023
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Toll-like receptor 9 (-1237 T/C,-1486 T/C) and the risk of gastric cancer: a meta-analysis of genetic association studies BMC CANCER 2023
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Association between IL-10 gene polymorphisms (− 1082 A/G,-819 T/C,-592 A/C) and hepatocellular carcinoma: a meta-analysis and trial sequential analysis BMC CANCER 2023
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Community engagement in health services research on soil-transmitted helminthiasis in Asia Pacific region: Systematic review PLOS GLOBAL PUBLIC HEALTH 2023
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Pteropine Orthoreovirus (PRV7S) does not Establish Persistent Infection in NP460 Cells but with Inflammatory Response Triggered BIOMEDICAL AND ENVIRONMENTAL SCIENCES 2023
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Clinicopathological study of gastric cancer in a Malaysian tertiary public health care centre THE MEDICAL JOURNAL OF MALAYSIA 2023
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Human cytokeratin 1 plays a role in the interaction of Pteropine orthoreovirus with Hek293 cells but not HeLa cells MICROBES AND INFECTION 2023
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RESEARCH ARTICLE Bat coronavirus was detected positive from insectivorous bats in Krau Wildlife Reserve Forest TROPICAL BIOMEDICINE 2023
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Loop-mediated isothermal amplification (LAMP) test in the detection of uncomplicated malaria in pregnancy: a meta-analysis of diagnostic accuracy MALARIA JOURNAL 2022
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Seroprevalence of Pteropine orthoreovirus (PRV) Infection among Outpatients in a Clinic in Rembau, Malaysia BIOMEDICAL AND ENVIRONMENTAL SCIENCES: BES 2022
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Seroprevalence of Pteropine orthoreovirus in humans remain similar after nearly two decades (2001–2002 vs. 2017) in Tioman Island, Malaysia JOURNAL OF MEDICAL VIROLOGY 2022
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Rapid diagnostic test (Leptocheck-WB) for detection of acute leptospirosis: a meta-analysis of diagnostic accuracy EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES 2022
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Pteropine Orthoreovirus, PRV7S (Sikamat Virus) Demonstrates Oncolysis in Nasopharyngeal Carcinoma Cell Lines FRONTIERS IN BIOSCIENCE-LANDMARK 2022
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Toll-like receptor 9 and 4 gene polymorphisms in susceptibility and severity of malaria: a meta-analysis of genetic association studies MALARIA JOURNAL 2021
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Dengue fever and insecticide resistance in Aedes mosquitoes in Southeast Asia: a review PARASITES & VECTORS 2021
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COVID-19 Sample Pooling: From RNA Extraction to Quantitative Real-time RT-PCR BIO-PROTOCOL 2021
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A novel strategy for community screening of SARS-CoV-2 (COVID-19): Sample pooling method PLOS ONE 2020
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Development of an optical biosensor for the detection of Trypanosoma evansi and Plasmodium berghei SPECTROCHIMICA ACTA PART A: MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 2019
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Association of tumour necrosis factor-α (TNF-α) gene polymorphisms (-308 G> A and-238 G> A) and the risk of severe dengue: A meta-analysis and trial sequential analysis PLOS ONE 2018
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Antioxidant and toxicity studies of 50% methanolic extract of orthosiphon stamineus benth BIOMED RESEARCH INTERNATIONAL 2013
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Redefining Vaccines: Nucleic Acid Vaccines Encoding Short Therapeutic Peptides AVAILABLE AT SSRN 4844142 2010
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Environmental health and building related illnesses JOURNAL OF SCIENCE, MEDICINE AND EDUCATION 2008
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DNA vaccine constructs against enterovirus 71 elicit immune response in mice GENETIC VACCINES AND THERAPY 2007


Supervisions
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Cindy Yeoh Shin Ly | Master (Research) | 20 Sep 2022 Thesis: Molecular mechanisms of toxicity induced by polyfluoroalkyl substances in human bronchial and alveolar epithelial cells
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Htet Htet | Doctorate | 24 Sep 2021 Thesis: The role of cytokines (interluekin and tumour necrosis factors) and the gene-gene interaction in Helicobacter pylori infected gastric cancer: A hospital based case-control study
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Sandya Menon | Doctorate | 31 Mar 2021 Thesis: Indoor air quality at primary healthcare clinics in Selangor
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Khoo Mee Teck | Doctorate | 01 Sep 2020 Thesis: System biology comparison between mice with single and co-infection from Toxoplasma gondii and/or Trypanosoma evansi