TAN BOON HOOI
Salutation
Dr
School/Centre
School of Health Sciences
Department
Applied Biomedical Science and BiotechnologyMedical Biotechnology
Position
Senior Lecturer
Email
Education
a
Doctor of Philosophy (PhD-Med), 2015
Monash University Malaysia
a
Master of Science (Genetic Engineering and Molecular Biology), 2009
Universiti Putra Malaysia
a
Bachelor of Science (Hons) (Biomedical Sciences), 2003
Universiti Putra Malaysia
Memberships
a
Malaysian Society for Biochemistry and Molecular Biology
Member
2024 - Present
a
Malaysia Board of Technologists (MBOT)
Graduate Technologists (GT)
2021 - Present
a
Malaysian Society for Biochemistry and Molecular Biology
Member
2018 - Present
Research Funding
a
Development and evaluation of immersive 360 virtual simulated scenarios for training and assessments in crime scene investigation
IMU Internal Research Grant | 19 Sep 2024 - 31 Dec 2025
a
Evaluation of cytochrome P450 inhibition potential of Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action: in vitro and in silico studies
IMU Internal Research Grant | 10 Jul 2023 - 30 Nov 2023
a
The inhibitory effects of osmanthus flower extracts on human cytochrome P450 3A4 (CYP3A4)
IMU Internal Research Grant | 01 Jun 2023 - 31 Dec 2023
a
Influence of micro- and nanoplastic (polystyrene micro- and nanosphere) on the combined toxicity of chromium (Cr) and cadmium (Cd) in microalgae
IMU Internal Research Grant | 01 Jun 2023 - 31 Dec 2023
a
n Vitro Inhibitory Effects of Human Cytochrome P450 Activity by Ag8, a silver-N-Heterocyclic Compound with Promising Anti-Cancer Action
IMU | 01 Jul 2019 - 01 Sep 2019
a
In vitro functional characterization of human cytochrome P450 2A13 (CYP2A13 variants involved in coumarin hydroxylase activity
IMU | 01 Jun 2019 - 01 Sep 2019
a
The effect of cytochrome P450 (CYP) 2D6 genetic polymorphism on inhibitory potency of phenytoin and sertraline
IMU Medical Biotechnology Project Grant | 03 Dec 2018 - 01 May 2019
a
Optimising the expression conditions of a recombinant human hepatic cytochrome P450 (CYP) in Escherichia coli.
IMU Medical Biotechnology Project Grant | 04 Dec 2017 - 01 May 2018
Publications
Research Articles
a
Mechanism-based Inactivation of Cytochromes P450: Implications in Drug Interactions and Pharmacotherapy
XENOBIOTICA 2024
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Cytochromes P450: Role in Carcinogenesis and Relevance to Cancers.
CURRENT DRUG METABOLISM 2022
a
In vitro inhibitory effects of glucosamine, chondroitin and diacerein on human hepatic CYP2D6
DRUG METABOLISM AND PERSONALIZED THERAPY 2021
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The CYP2R1 Enzyme: Structure, Function, Enzymatic Properties and Genetic Polymorphism
JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES 2021
a
Expression of cytochrome P450 2C9 (CYP2C9) in Escherichia coli and its functional characterization
ASIA-PACIFIC JOURNAL OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY 2019
a
Cytochrome P450 genotype‐guided drug therapies: an update on current states
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 2018
a
Cytochrome P450 2C9‐natural antiarthritic interactions: Evaluation of inhibition magnitude and prediction from in vitro data
BIOPHARMACEUTICS & DRUG DISPOSITION 2018
a
Prevalence, virulence genes and antimicrobial resistance profiles of Salmonella serovars from retail beef in Selangor, Malaysia
FRONTIERS IN MICROBIOLOGY 2018
a
In vitro and in silico approaches to study cytochrome P450-mediated interactions
JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES 2017
a
The use of natural remedies to treat osteoarthritis
CELLMED 2016
a
Molecular characterization of a recombinant manganese superoxide dismutase from Lactococcus lactis M4
BIOMED RESEARCH INTERNATIONAL 2014
Other Publications
a
Exploring the Inhibitory Effect of Osmanthus Flower Aqueous Extracts on Human Cytochrome P450 (CYP) through in vitro and in silico Approaches
33rd Intervarsity Biochemistry Seminar | 09 Dec 2023
a
Establishment of a high-throughput fluorescence-based assay for in vitro catalytic activity of cytochrome P450 2D6
The 8th International Conference on Biomedical Engineering and Biotechnology | 22 Oct 2019
a
EXPRESSION OF A RECOMBINANT HUMAN HEPATIC CYTOCHROME P450 3A4 IN ESCHERICHIA COLI – OPTIMISATION OF THE INDUCTION TIME
International Conference on Biochemistry, Molecular Biology and Biotechnology | 15 Aug 2018
a
Optimisation of the expression temperature of a recombinant human hepatic cytochrome P450 3A4
International Conference on Biochemistry, Molecular Biology and Biotechnology | 15 Aug 2018
a
Effects of glucosamine, chondroitin and diacerein on human hepatic cytochrome P450 3A4 activity in vitro
The XIII International Congress of Toxicology | 30 Jun 2013
Books
a
Jenny Stanford Publishing (2019). Cytochromes P450, Cardiovascular Homeostasis and Disease
Supervisions
a
Gan Su Ee | Undergraduate | 10 Jul 2023 - 30 Nov 2023
Thesis: Evaluation of cytochrome P450 inhibition potential of Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action: in vitro and in silico study
a
Leong Khai Qian | Undergraduate | 01 Jun 2023 - 31 Dec 2023
Thesis: THE INHIBITORY EFFECT OF OSMANTHUS FLOWER ETHANOL EXTRACT ON HUMAN CYTOCHROME P450 3A4 (CYP3A4) AND CYTOCHROME P450 2C9 (CYP2C9)
a
Rachelle Chin Yun Yeen | Undergraduate | 01 Jun 2023 - 31 Dec 2023
Thesis: THE INHIBITORY EFFECT OF OSMANTHUS FLOWER AQUEOUS EXTRACT ON HUMAN CYTOCHROME P450 2C9 (CYP2C9) AND 3A4 (CYP3A4)
a
Sandra Khoo Su Min | Undergraduate | 01 Jun 2019 - 31 Oct 2019
Thesis: In vitro inhibitory effects of CYP2C9 activity by Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action
a
Lau Rui Ying | Undergraduate | 01 Jun 2019 - 31 Oct 2019
Thesis: In vitro inhibitory effects of CYP3A4 activity by Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action
a
Ng Si Shun | Undergraduate | 01 Jun 2019 - 31 Oct 2019
Thesis: In vitro inhibitory effects of CYP2D6 activity by Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action
a
Phang Jia Chern | Undergraduate | 01 Jun 2019 - 31 Oct 2019
Thesis: In vitro inhibitory effects of CYP1A2 activity by Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action
a
Dhirmall A/L Selvakumar | Undergraduate | 01 Apr 2019 - 30 Nov 2019
Thesis: In vitro functional characterisation of human cytochrome P450 2A13 (CYP2A13) variants involved in coumarin hydroxylase activity
a
Choy Sze Mun | Undergraduate | 01 Dec 2018 - 31 May 2019
Thesis: THE EFFECT OF CYTOCHROME P450 (CYP) 2D6*1 AND *10 ON THE INHIBITORY POTENCY OF SERTRALINE AND PHENYTOIN.
a
Lim Kai Shen | Undergraduate | 01 Dec 2018 - 31 May 2019
Thesis: The effect of cytochrome P450 (CYP) genetic polymorphism on inhibitory potency of phenytoin and sertraline
a
Chong Ce Lynn | Undergraduate | 01 Dec 2018 - 31 May 2019
Thesis: The Effect of Cytochrome P450(CYP) 2D6 Allele 10 and Allele 14A on Inhibitory Potency of Sertraline
a
Ng Aivon | Undergraduate | 01 Dec 2017 - 31 May 2018
Thesis: OPTIMIZING THE INDUCTION TIME FOR THE EXPRESSION OF A RECOMBINANT HUMAN HEPATIC CYTOCHROME P450 (CYP) IN ESCHERICHIA COLI
a
Ong Bee Chia | Undergraduate | 01 Dec 2017 - 31 May 2018
Thesis: OPTIMIZING THE EXPRESSION TEMPERATURE OF A RECOMBINANT HUMAN HEPATIC CYTOCHROME P450 IN ESCHERICHIA COLI