Lee Choy Sin



Salutation
Associate Professor Dr

School/Centre
School of Pharmacy

Appointment
Associate Dean, Research & Consultancy

Position
Associate Professor

Email
choysin_lee@imu.edu.my

Professional Network


Education

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PhD (Chemistry), 2008 University Malaya
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BSc (Applied Chemistry), 2003 University Malaya

Memberships

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Institut Kimia Malaysia Member 2022 - Present
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Malaysian Oils Scientists’ and Technologists’ Association Council Member 2013 - Present

Research Funding
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Preparation, Characterisation And Solubility Study Of Poorly Water-Soluble Drug In Polyurethane Nanoparticles IMU Internal Research Grant | 17 Mar 2025 - 24 May 2025
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Tocotrienol loaded modulated metal-organic framework IMU Internal Research Grant | 01 Mar 2025 - 28 Feb 2027
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Metal-Organic Framework-Hydrogel for Wound Healing IMU Internal Research Grant | 01 Feb 2025 - 31 Jan 2028
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Evaluation of Trans-Fatty Acids and Oxidation Products in Malaysia Food Products for Public Health Impact IMU Internal Research Grant | 01 Dec 2024 - 31 Mar 2026
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Development of a Natural Rubber Latex (NRL) with Palm Oil-Based Prepolymer: Evaluation of Physico-Chemical, Mechanical, and Degradation Properties IMU Internal Research Grant | 21 Oct 2024 - 28 Dec 2024
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Metal-Organic Frameworks as Drug Delivery Vehicles: Investigating Cellular Uptake and Efficacy in In-Vitro Assays IMU Internal Research Grant | 01 Jun 2024 - 30 Sep 2024
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Photoprotective Bioactivity of Microalgae Extracts on Ultraviolet Light-Irradiated Human Keratinocytes IMU Internal Research Grant | 01 Jun 2023 - 31 Dec 2023
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Photoprotective Potential of Mycosporine-Like Amino Acids (MAAs) and Bioactive Compounds from Antarctic Microalgae on Human Keratinocytes IMU Internal Research Grant | 01 Mar 2023 - 28 Feb 2026
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Fabrication of surface-active food biopolymer as nutraceutical delivery system: Conjugation of pea protein isolate with quercetin IMU Internal Research Grant | 01 Dec 2022 - 31 Aug 2023
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Quality by Design approach to optimise spray drying process in the development of nano-tocotrienol dry powder IMU Internal Research Grant | 29 Nov 2022 - 30 Jul 2023
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Molecular mechanisms of toxicity induced by polyfluoroalkyl substances in human bronchial and alveolar epithelial cells FRGS | 07 Sep 2021 - 06 Sep 2023
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Ecotoxicolgical Joint Effects of Nanoplastic and Herbicide Atrazine on Microalgae: Physiological and Molecular Responses FRGS | 07 Sep 2021 - 06 Sep 2024
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Molecular mechanisms of toxicity induced by nanoplastics in human cells FRGS | 01 Nov 2020 - 31 Oct 2022
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Development and biological evaluations of novel palm oil-based metal-organic frameworks (MOFs) for drug delivery MPOB R&D Grant | 01 Aug 2020 - 01 Aug 2023
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Influence of micro- and nanoplastic (polyethylene micro- and nanosphere) on the combined toxicity of copper and cadmium in microalgae FRGs | 01 Jan 2020 - 31 Mar 2023
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“Smart” Palm Oil-Based Polyurethane-Acrylate with pH, Light and Thermal Responsive Properties: An Isocyanate-free Route FRGS | 01 Sep 2019 - 31 May 2023
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Hyperbranched Polyglycerol-ester-amide as Drug Carrier for Solid Dispersion: Synthesis, Formulation and in vitro studies MPOB GSAS Grant | 01 Jul 2016 - 01 Jul 2018
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Metal-incorporated polyester coating: Synthesis, characterisation and antimicrobial studies MPOB GSAS Grant | 01 Oct 2013 - 01 Oct 2015
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Preparation of a palm oil-based lipid nanoparticle topical formulation MPOB GSAS Grant | 01 Mar 2012 - 01 Mar 2014
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Production of biocompatible and biodegradable water blown porous polyurethane scaffolds from palm oil-based polyester polyol and cellulose nanocrystals for tissue engineering ERGS | 01 Jan 2012 - 01 Jul 2014
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Synthesis and antifungal activity of metal incorporated polyesteramide from used frying oil Japan Toray Foundation | 01 Dec 2011 - 01 Dec 2013

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Publications

Research Articles

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Adaptations, Cultivation, and Commercial Prospects of Polar Microalgae ADVANCES IN POLAR SCIENCE 2025
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NIR-induced photothermal-responsive shape memory polyurethane for versatile smart material applications RSC ADVANCES 2024
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Stimulus-responsive MOF–hydrogel composites: Classification, preparation, characterization, and their advancement in medical treatments OPEN CHEMISTRY 2024
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pH‐responsive polyurethane‐acrylate from palm olein and sunflower oil: Sustainable synthesis, enhanced lovastatin solubility, and potential drug carrier for targeted delivery JOURNAL OF APPLIED POLYMER SCIENCE 2024
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Non‐isocyanate polyurethane‐acrylate as UV‐and thermo‐responsive plasticizer for thermoplastic elastomer JOURNAL OF APPLIED POLYMER SCIENCE 2024
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Prospecting bioactivity in Antarctic algae: A review of extracts, isolated compounds and their effects FITOTERAPIA 2024
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Light-responsive polyurethanes: classification of light-responsive moieties, light-responsive reactions, and their applications RSC ADVANCES 2022
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PH Responsive Polyurethane for the Advancement of Biomedical and Drug Delivery POLYMERS 2022
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Investigation of hyperbranched Poly (glycerol esteramide) as potential drug carrier in solid dispersion for solubility enhancement of lovastatin JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 2021
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Influence of polystyrene microplastic and nanoplastic on copper toxicity in two freshwater microalgae ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 2021
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Hyperbranched poly (glycerol esteramide): A biocompatible drug carrier from glycerol feedstock and dicarboxylic acid JOURNAL OF APPLIED POLYMER SCIENCE 2021
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Production of biodegradable palm oil-based polyurethane as potential biomaterial for biomedical applications POLYMERS 2020
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The evaluation of students’ written reflection on the learning of general chemistry lab experiment MOJES: MALAYSIAN ONLINE JOURNAL OF EDUCATIONAL SCIENCES 2018
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Distribution of microplastics and nanoplastics in aquatic ecosystems and their impacts on aquatic organisms, with emphasis on microalgae REVIEWS OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY VOLUME 246 2018
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One‐pot synthesis of palm oil‐based polyester polyol for production of biodegradable and biocompatible polyurethane JOURNAL OF APPLIED POLYMER SCIENCE 2018
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Biocompatible palm stearin‐based polyesteramide as polymer carrier for solid dispersion JOURNAL OF APPLIED POLYMER SCIENCE 2018
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One‐pot synthesis of cobalt‐incorporated polyglycerol ester as an antimicrobial agent for polyurethane coatings JOURNAL OF APPLIED POLYMER SCIENCE 2018
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Biocompatible polyurethane scaffolds prepared from glycerol monostearate-derived polyester polyol JOURNAL OF POLYMERS AND THE ENVIRONMENT 2018
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Preparation and modification of water-blown porous biodegradable polyurethane foams with palm oil-based polyester polyol INDUSTRIAL CROPS AND PRODUCTS 2017
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Preparation and optimization of palm-based lipid nanoparticles loaded with griseofulvin IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH: IJPR 2017
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Preparation and evaluation of palm oil-based polyesteramide solid dispersion for obtaining improved and targeted dissolution of mefenamic acid JOURNAL OF PHARMACEUTICAL INNOVATION 2017
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In-vitro evaluation of griseofulvin loaded lipid nanoparticles for topical delivery JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY 2016
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Synthesis of palm oil‐based polyester polyol for polyurethane adhesive production JOURNAL OF APPLIED POLYMER SCIENCE 2014
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Polyurethane wood adhesive from palm oil-based polyester polyol JOURNAL OF ADHESION SCIENCE AND TECHNOLOGY 2014
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Preparation of polyester polyol from epoxidized palm olein CHINESE JOURNAL OF CHEMISTRY 2011
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The effect of reaction temperature on retaining oxirane oxygen contents in the synthesis of epoxidized diethanolamides AMERICAN JOURNAL OF APPLIED SCIENCES 2009
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Effect of isocyanate index on physical properties of flexible polyurethane foams MALAYSIAN JOURNAL OF SCIENCE 2007
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Synthesis of palm oil-based diethanolamides JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY 2007
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Rigid polyurethane foam production from palm oil‐based epoxidized diethanolamides JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY 2007

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Other Publications

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Embracing Sustainable Development Goals: Leveraging Synthetic Polymers from Renewable Feedstocks for Biomedical and Pharmaceutical Applications UM Nanotechnology and Catalysis Research Centre (NANOCAT) Seminar | 20 Mar 2024
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The Emergence of Synthetic Polymers from Renewable Feedstocks for Biomedical and Pharmaceutical Applications Virtual International Research Network Initiative (IRNI) and International Postgraduate Conference on Pharmaceutical Sciences (IPoPS) 2021 | 28 Sep 2021

Patents

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A Pharmaceutical Copolymer and Method of Preparing Thereof | 13 Nov 2018
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Metal-incorporated polyester and polyester-amide coating: Synthesis, characterisation and antimicrobial studies | 07 Oct 2015


Supervisions
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Chua Bing Wei | Doctorate | 01 Aug 2020 Thesis: Developing of Metal Organic Frameworks for Drug Delivery
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Toh Jia En | Master (Research) | 01 Aug 2020 Thesis: Palm oil-based metal organic frameworks (MOFs) via a non-conventional synthetic approach
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Rachel Tan Yie Hang | Master (Research) | 01 Dec 2019 Thesis: Synthesis and Characterisation of pH Responsive Non-Isocyanate Polyurethane as a Drug Carrier
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Lam Ki Yan | Master (Research) | 01 Nov 2019 Thesis: Thermo and Photo Responsive Polyurethane: Synthesis, Characterisation and In-Vitro studies
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Wong Hiew Yi (Defer due to health issue) | Master (Mixed Mode) | 01 Sep 2017 - 01 Nov 2020 Thesis: Development of a stable amorphous polyesteramide solid dispersion formulations by solvent evaporation method technique
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Hoe Yim Teng | Master (Mixed Mode) | 01 Jan 2017 - 01 Jan 2018 Thesis: Effect of bio-based polyester polyol plasticiser as replacement of petroleum oil in thermoplastic elastomer for medical devices
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Wan Jun Kit | Master (Research) | 01 Dec 2016 - 01 Jul 2019 Thesis: Effects of Microplastics and Nanoplastics on the Toxicity of Copper in Microalgae
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Amala Muniandy | Master (Research) | 01 Jul 2016 - 01 Dec 2018 Thesis: Hyperbranched Polyglycerol-ester-amide as Drug Carrier for Solid Dispersion: Synthesis, Formulation and In-vitro studies
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Chua Bing Wei | Master (Research) | 01 Oct 2013 - 01 Mar 2016 Thesis: Metal-incorporated polyester and polyester-amide coating: Synthesis, characterisation and antimicrobial studies
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Wong Wei Seng | Master (Research) | 01 Oct 2013 - 01 Mar 2016 Thesis: Palm Oil-based Polyesteramide as Functional Material for Solid Dispersion
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Yeoh Fang Hoong | Master (Research) | 01 Oct 2013 - 01 Mar 2016 Thesis: Synthesis a Biocompatible and Biodegradable Waterborne Porous Polyurethane Scaffold from Palm oil-based Polyester Polyol for Tissue Engineering
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Ng Wei Seng | Doctorate | 01 Jan 2013 - 01 Jul 2016 Thesis: Synthesis, Characterisation and Evaluation of Palm Oil-based Polyuretahne Scaffolds as Candidate Biomaterial
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Tan Yann Jean | Master (Research) | 01 Dec 2012 - 01 Jun 2015 Thesis: Preparation of palm-based lipid nanoparticle formulation containing antifungal active compounds
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Ang Khoon Poh | Master (Research) | 01 Aug 2009 - 01 Apr 2012 Thesis: Synthesis of Palm Oil-based Polyol and its Application in Polyurethane Adhesives for Wood

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