CAROLINA SANTIAGO A/P ROBERT



Salutation
Dr

School/Centre
School of Medicine

Department
Biochemistry

Position
Senior Lecturer


Professional Network


Education

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PhD (Biomedical Science), 2015 University of Nottingham
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MSc (Health Science-Biomedical Science), 2010 Universiti Kebangsaan Malaysia
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BSc (Biotechnology), 2006 Universiti Industri Selangor

Research Funding
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Post-prandial hyperglycemia during Ramadan fasting using a 24-hour continuous glucose monitoring system in Malaysian individuals. IMU Internal Research Grant | 01 Jan 2025 - 01 Oct 2026
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Enhancing the Remediation Process in Pre-Clinical Medical Programme IMU Internal Research Grant | 01 Sep 2024 - 30 Sep 2025
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Synthesis, Characterisation and In Vitro Biological Evaluation of a series of Novel Benzothiazole Derivatives as Antimicrobial Agents IMU Internal Research Grant | 01 Nov 2020 - 30 Apr 2021
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Short-term meditation in Mild Cognitive Impairment (MCI): Study on neuro-metabolites and enzymes in kynurenine pathway (KP) MoHE Fundamental Research Grant Scheme (FRGS) | 01 Nov 2020 - 31 Oct 2022
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Preliminary screening of Salvia chinensis Benth, a traditional Chinese medicinal plant, for anti-pancreatic cancer activity IMU | 19 Jul 2019 - 19 Dec 2019
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Determination of Bioactive Fractions with Activity Against methicilin-resistant Staphylococcus aureus (MRSA) from a Paenibacillus polymyxa Extract IMU | 18 Jul 2018 - 18 Dec 2018
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Evaluation of Antimicrobial Activity of Antarctica Fungal Alkaloids on Antibiotic-Resistant Escherichia coli strains IMU | 31 Dec 2017 - 31 May 2018
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Effect of Antarctica fungal alkaloid extracts on indole production in antibiotic-resistant Escherichia coli strains IMU | 01 Jun 2017 - 31 Jan 2018
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Extraction and evaluation of antimicrobial activity of Crescentia cujete IMU | 01 May 2017 - 31 Oct 2017
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Evaluation of Growth Condition for Production of Secondary Metabolites in Fungal Isolates from Antarctica Soil IMU | 05 Dec 2016 - 31 May 2017

Publications

Research Articles

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Surviving the COVID-19 Pandemic: Lessons Learnt and Experience of a Private Medical School in Malaysia. EDUCATION IN MEDICINE JOURNAL 2023
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MIND-BODY THERAPIES AND ITS EFFECT ON THE IMMUNE SYSTEM IN CHRONIC DISEASES: A LITERATURE REVIEW JOURNAL OF HEALTH AND TRANSLATIONAL MEDICINE 2022
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Effects of combination of phenazine-1-carboxylic acid from Streptomyces kebangsaanensis with amphotericin B on clinical Fusarium solani species MALAYSIAN JOURNAL OF MICROBIOLOGY 2020
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Inhibition of penicillin-binding protein 2a (PBP2a) in methicillin resistant Staphylococcus aureus (MRSA) by combination of ampicillin and a bioactive fraction from Duabanga grandiflora BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE 2015
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Inhibitory effect of Duabanga grandiflora on MRSA biofilm formation via prevention of cell-surface attachment and PBP2a production MOLECULES 2015
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Prevention of cell-surface attachment and reduction of penicillin-binding protein 2a (PBP2a) level in methicillin-resistant Staphylococcus aureus biofilms by Acalypha wilkesiana BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE 2015
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Polyketide and benzopyran compounds of an endophytic fungus isolated from C innamomum mollissimum: biological activity and structure ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE 2014
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Reversal of ampicillin resistance in MRSA via inhibition of penicillin-binding protein 2a by Acalypha wilkesiana BIOMED RESEARCH INTERNATIONAL 2014
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Cytotoxic and antifungal activities of 5-hydroxyramulosin, a compound produced by an endophytic fungus isolated from Cinnamomum mollisimum EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2012
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Reversal of ampicillin resistance in MRSA via inhibition of penicillin-binding protein 2a by Acalypha GENES AND DEVELOPMENT 1998

Other Publications

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Natural Products -Discovery and Development in the age of AI NIBM Science Cafe | 20 Oct 2022
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Application of Acalypha wilkesiana extracts to overcome resistance of methicillin resistant Staphylococcus aureus (MRSA) 31st Symposium of the Malaysian Society for Microbiology | 13 Dec 2021
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Antarctica Fungi 8th Malaysian International Seminar on Antarctica | 18 Jun 2019
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Inhibitory effect of Acalypha wilkesiana and Duabanga grandiflora on MRSA biofilm formation via prevention of cell-surface attachment and PBP2a production. School of Biomedical Science Symposium | 24 Jul 2015
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Bioactive plant metabolites reverse resistant of MRSA biofilms to ampicillin III International Conference on Antimicrobial Research | 01 Oct 2014
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Inhibition of beta-lactamase and penicillin binding protein 2a. 15th International Biotechnology Symposium and Exhibition | 16 Oct 2012
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Endophytic fungi Faculty of Science Research Talk | 27 Jun 2012
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Anti-methicillin resistant Staphylococcus aureus (MRSA) activity of combination of antibiotic and ethyl acetate extract from Acalypha wilkesiana International Conference on Natural Products | 13 Nov 2011
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Inhibition of penicillin binding protein (PBP2a) production in methicillin-resistant Staphylococcus aureus (MRSA). MPS-Pharmacy Scientific Conference | 21 Oct 2011
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Anti-Methicillin resistant Staphylococcus aureus (MRSA) activity of ethyl acetate extract from Acalypha wilkesiana. MPS-Pharmacy Scientific Conference | 21 Oct 2011
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The presence of Menisporopsin A in endopyhtic actinomycetes isolated from Cinnamomum partheoxylon. Malaysian Natural Product International Seminar | 23 Nov 2009
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Anti-Candida activity in Endophytic fungi isolated from Rafflesia cantleyi Asian Mycology Congress | 15 Nov 2009
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5-Hydroxyramulosin, a cytotoxic compound from an endopythic fungus in Cinnamomum sp. Darwin 2009 Commemoration: International Conference on Fungal Evolution | 09 Jul 2009
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Antimicrobial activity of endophytic fungi from selected medicinal plants Biodiversity and Biotechnology Symposium | 09 Nov 2008
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Antimicrobial activity of endophytic fungi International Mycology Conference | 05 Aug 2008
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Isolation of endophytic fungi Asian Mycology Conference | 03 Dec 2007


Supervisions
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Mya Thinzar | Master (Research) | 01 Nov 2020 - 31 May 2023 Thesis: Short-term meditation in Mild Cognitive Impairment (MCI): Study on neuro-metabolites and enzymes in kynurenine pathway (KP)
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Hadyah Mohammed Alazma’a | Master (Research) | 01 Nov 2020 - 30 Apr 2021 Thesis: Synthesis, Characterisation and In Vitro Biological Evaluation of a series of Novel Benzothiazole Derivatives as Antimicrobial Agents
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Choong Qi Ying, Prathiba Vijayagomaran, Lee Jing Ying, Ong Jing Qi | Undergraduate | 19 Jul 2019 - 19 Dec 2019 Thesis: Preliminary screening of Salvia chinensis Benth, a traditional Chinese medicinal plant, for anti-pancreatic cancer activity
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Hong Ang Chee, Lee Ke Qing, Ong Siu Lyn, Joan Wong | Undergraduate | 18 Jul 2018 - 18 Dec 2018 Thesis: Determination of Bioactive Fractions with Activity Against methicilin-resistant Staphylococcus aureus (MRSA) from a Paenibacillus polymyxa Extract
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Goh Guan Zuo, Tan Yi Ling, Naveenthar A/L Mohan | Undergraduate | 31 Dec 2017 - 31 May 2018 Thesis: Evaluation of Antimicrobial Activity of Antarctica Fungal Alkaloids on Antibiotic-Resistant Escherichia coli strains
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Tan Jing Ru, Sim Serjay | Undergraduate | 01 Jun 2017 - 31 Jan 2018 Thesis: Effect of Antarctica fungal alkaloid extracts on indole production in antibiotic-resistant Escherichia coli strains
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Jeremiah Chee Choong Sern, Tan Siow Jean, Ng Chia Shyn, Loy Kuang Yew | Undergraduate | 01 May 2017 - 31 Oct 2017 Thesis: Extraction and evaluation of antimicrobial activity of Crescentia cujete
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Brenda, Cassandra, Tham Soon Min | Undergraduate | 05 Dec 2016 - 31 May 2017 Thesis: Evaluation of Growth Condition for Production of Secondary Metabolites in Fungal Isolates from Antarctica Soil
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Nor Afifa binti Mazlan | Master (Coursework) | 01 Jan 2015 - 31 Jan 2017 Thesis: Determination of antifungal effect of microbial metabolites against Fusarium spp. Isolates