OOI ING HONG



Salutation
Associate Professor Dr

School/Centre
School of Pharmacy

Department
Pharmaceutical Chemistry

Position
Associate Professor

Email
inghong_ooi@imu.edu.my



Education

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PhD (Polymer Science), 1998 University of Akron, Ohio, USA
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MSc (Chemistry), 1989 Universiti Malaya
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BSc (Hons) (Chemistry), 1986 University Malaya

Memberships

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Royal Society of Chemistry Member; Malaysia chapter committee 2015 - 2024
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Institut Kimia Malaysia member; Joint-Technical committee 2013 - 2024
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American Chemical Society member 1997 - 2024

Research Funding
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Non-ionic surfactant Niosomes Membrane Rigidity and Stability IMU Internal Research Grant | 18 Jun 2024 - 25 Sep 2024
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Hydrophilic drug loaded niosomes: effect of cholecalciferol its functional properties and stability IMU Internal Research Grant | 18 Mar 2024 - 25 May 2024
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Hydrophobic drug loaded niosome: effect of cholecalciferol on its functional properties and stability IMU Internal Research Grant | 18 Mar 2024 - 25 May 2024
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Functional properties and stability of resveratrol loaded Span60/Tween60 based niosomes with vitamin D as vesicular stabilizer IMU Internal Research Grant | 29 May 2023 - 06 Mar 2024
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Effects of Organic Solvents on IC50 of Various Antioxidant Standard Determined Via DPPH Radical Scavenging Assay IMU Internal Research Grant | 27 Mar 2023 - 03 Jun 2023
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Docking, synthesis and anticancer studies of amides of polyunsaturated fatty acids (PUFA) and nucleosides as inhibitors of epigenetic modifier PRC2/EZH2 BMedSc | 01 Jan 2021 - 30 Apr 2021
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Esterified Bis-GMA as Potential Monomers for Dental Restorative Composite Materials: Synthesis and Physico-Mechanical Properties Evaluation IMU | 01 Sep 2020 - 01 Nov 2020
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Evaluation of Esterified Bis-GMA as a Potential Monomer for Dental Restorative Composite Materials IMU | 01 Apr 2020 - 01 Jun 2020
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Effects of Molecular Spacer on Pullulan based Polysaccharide Functional Film properties IMU | 01 Jul 2019 - 01 Oct 2019
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Factors affecting anticancer property of nanogold-ternary metal complex conjugates FRGS | 01 May 2014 - 30 Oct 2016
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Synthesis, Characterisation and Evaluation of Amphiphilic Star-branched Folate-Terminated PLA-(PEG)2 Block Copolymers as Nanocarriers for Targeted Drug Delivery MOSTI eScience | 01 Aug 2013 - 31 Jan 2016
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Star-Shaped Copolymer Poly (Lacyide-co-Glycolide)-b-(Monomethoxy Poly(Ethylene Glycol))2 [PLGA-b-(MPEG)2] as Nanocarriers for Drug Delivery: Synthesis, Characterisation, and In Vitro Drug Release Study FRGS | 01 Jul 2013 - 30 Jun 2015
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Enantiomeric pairs of copper(II) polypyridyl-alanine complex salts: anticancer studies MOSTI eScience | 01 Jul 2013 - 30 Jun 2015
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Fucosterol inhibits the cholinesterase activities and e-Science | 01 Jul 2012 - 30 Jun 2014

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Publications

Research Articles

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Effect of 2, 2, 2-trifluoroethyl methacrylate: Triethyleneglycol dimethacrylate ratio on functional properties of Bis-GMA hybrid composites POLYMERS AND POLYMER COMPOSITES 2022
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Synthesis and Characterization of the Nanogold-Bound Ternary Copper (II) Complex of Phenanthroline and Cysteine as Potential Anticancer Agents ACS OMEGA 2022
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Zinc (II)-Schiff base complex functionalized on gold nanospheres: synthesis, characterization, anticancer study and interaction with proteins JOURNAL OF COORDINATION CHEMISTRY 2022
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Dendrimer-like AB2-type star polymers as nanocarriers for doxorubicin delivery to breast cancer cells: synthesis, characterization, in-vitro release and cytotoxicity studies JOURNAL OF POLYMER RESEARCH 2020
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Effect of trifluoroethyl methacrylate comonomer on physical properties of Bis-GMA based dental composites DENTAL MATERIALS JOURNAL 2019
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Miktoarm star polymers nanocarrier: synthesis, characterisation, and in-vitro drug release study JOURNAL OF POLYMER RESEARCH 2019
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Enantiomeric pairs of copper (II) polypyridyl-alanine complex salts: anticancer studies TRANSITION METAL CHEMISTRY 2018
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Fast gradient normal-phase high pressure liquid chromatography for rapid baseline separation of nine vitamin E homologues in palm tocotrienol rich fraction (TRF) ANALYTICAL METHODS 2017
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Ternary and binary copper (II) complexes: synthesis, characterization, ROS-inductive, proteasome inhibitory, and anticancer properties JOURNAL OF COORDINATION CHEMISTRY 2017
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Rac-aqua (4-methyl-oxazolidine-4-carboxylato)(nitrato)(1, 10-phenanthroline) copper (II), the aldol condensation product of formaldehyde with the d-and l-(alaninato) aqua (1, 10-phenanthroline) copper (II) nitrate TRANSITION METAL CHEMISTRY 2016
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Structural characterization, ROS-inductive and proteasome inhibitory properties of ternary and binary copper (II) complexes of N2-and N2O2-ligands INORGANICA CHIMICA ACTA 2016
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Preparation of temozolomide-loaded nanoparticles for glioblastoma multiforme targeting—Ideal versus reality PHARMACEUTICALS 2016
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Sunitinib DDI with paracetamol, diclofenac, mefenamic acid and ibuprofen shows sex-divergent effects on the tissue uptake and distribution pattern of sunitinib in mice CANCER CHEMOTHERAPY AND PHARMACOLOGY 2016
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Enantiomeric pair of copper (II) polypyridyl-alanine complexes: Effect of chirality on their interaction with biomolecules JOURNAL OF INORGANIC BIOCHEMISTRY 2016
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Hydrated and anhydrous forms of copper (II) complex of 3-methylpicolinic acid, and spectroscopic studies of their ROS-inducing and proteasome inhibition JOURNAL OF MOLECULAR STRUCTURE 2016
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Effects of Microemulsion Conditions on Drug Encapsulation Efficiency of Salicylic Acid in PLGA Microparticles ASIAN JOURNAL OF CHEMISTRY 2015
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Design, Synthesis and Pharmacological Properties of Peptidomimetics ASIAN JOURNAL OF CHEMISTRY 2015
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Swelling properties of poly (N-isopropylacrylamide)/calcium alginate interpenetrating polymer network hydrogel containing zirconia ASIAN JOURNAL OF CHEMISTRY 2015
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Effects of Microemulsion Preparation Conditions on Drug Encapsulation Efficiency of PLGA Nanoparticles AIP CONFERENCE PROCEEDINGS 2011
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Synthesis and properties of phenylethynyl-terminated, star-branched, phenylquinoxaline oligomers POLYMER 2000
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Synthesis and characterization of phyelethynyl-terminated, star-branched, phenylquinoxaline oligomers for adhesive and composite applications 44 TH INTERNATIONAL SAMPE SYMPOSIUM AND EXHIBITION 1999
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Synthesis of a palm‐based star‐shaped hydrocarbonvia oleate metathesis JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY 1996
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Synthesis of civetone from palm oil products JOURNAL OF THE AMERICAN OIL CHEMISTS' SOCIETY 1994
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Bis [(trimethylsilyl) ethynyl] ether: a moderately stable C4H2O derivative THE JOURNAL OF ORGANIC CHEMISTRY 1989

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Other Publications

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HYDROPHOBIC DRUG-LOADED SPAN-60 NIOSOME: EFFECT OF CHOLECALCIFEROL ON ENCAPSULATION EFFICIENCY AND NIOSOMAL STABILITY International Pharmacy and Pharmaceutical Science Conference (IPPSC2024) | 29 Jul 2024
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IN VITRO ANTIOXIDATIVE, ANTI-CHOLINESTERASE, ANTI-α-GLUCOSIDASE AND ALBUMIN DENATURATION INHIBITORY ACTIVITIES OF GELATIN-PHENOLIC ACID CONJUGATES International Undergraduate Medical Research Conference 2022 (IUMRC22) | 08 Nov 2022
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Effects of TFEMA on composites’ fluoride release and recharge capabilities The 44th APDSA Annual Congress 2017 | 01 Aug 2017
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Star-Branched Folate-Conjugated PLLA-PEG Copolymers as Nanocarriers for Targeted Delivery of Doxorubicin. Pusat Permata Pintar, University Kebangsaan Malaysia, Bangi, Selangor, Malaysia, 20 July 2017. Malaysia Polymer International Conference (MPIC) 2017 | 20 Jul 2017
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Effect of Fluorinated Diluent Monomer (TFEMA) on Critical Properties of Bis-GMA Based Dental Composites The 9th NDSSC | 06 May 2017
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Mikto-arm copolymer nanoparticles: synthesis, characterisation and in vitro release of paclitaxel. IMU Undergraduate Research Symposium 2016 | 05 Nov 2016
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In Vitro Studies of Mikto-arm Copolymers of Poly(ethylene glycol) (PEG) and Poly(Lactide-co-Glycolide) (PLGA) as Drug Delivery System. IMU Undergraduate Research Symposium 2016 | 05 Nov 2016
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In Vitro Release Studies of Paclitaxel Loaded in Mikto-arm Copolymer Nanoparticles. IMU Undergraduate Research Symposium 2016 | 05 Nov 2016
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Zn(II) Complexes and their nano gold conjugates: Cellular Imaging, anticancer and other biological application ICMSNT 2016, Seoul National University | 12 May 2016
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Thermo-Responsive Properties of Poly(N-isopropylacrylamide) /Poly(methacrylic-co-ferulic acid) Semi Interpenetrating Polymer Network Hydrogels ICMSNT 2016, Seoul National University | 12 May 2016
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Folate-Conjugated Star Branched PLLA-b-(PEG)2 Copolymer as Nanocarrier for Targeted Delivery. Annual Conference and Expo on Biomaterials 2016, Crowne Plaza Hotel, Heathrow, London, 14 March 2016 Annual Conference and Expo on Biomaterials 2016 | 14 Mar 2016
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Effect of Fluoride-containing Monomethacrylate Monomer (FMMA) Content on the Water Sorption, Fluoride Release, Degree of Conversion and Solubility of Bis-GMA/TEGDMA/UEDMA Based Dental Restorative Composite Asia Pacific Dental Student Association Conference (APDSA) | 17 Aug 2015
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Synthesis and Characterization of Star-branched Poly(L-lactide) by Ring-Opening Polymerization Pharmacy and Pharmaceutical Sciences Conference (PPSC) 2015 | 02 Aug 2015
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The effect of fluoride-containing monomethacrylate monomer (FFMA) content on the degree of curing, solubility, water sorption and fluoride release rate of Bis-GMA/TEGDMA/UEDMA based dental restorative composite, to be presented in the 7th NDSSC, IIUM, 15-17 May 2015 The 7th NDSSC, IIUM | 15 May 2015
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Effect of chirality on interaction with DNA and serum, proteasome inhibition and anticancer property of enantiomeric ternary copper(II) complexes The 7th Asian Biological Inorganic Chemistry Conference, Gold Coast | 30 Nov 2014
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Multitargeting anticancer metallodrugs: ROS-induced DNA damage, proteasome inhibition, mitochondria damage, topoisomerase I inhibition and in vivo studies The Vietnam Malaysia International Chemical Congress | 07 Nov 2014
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Nanogold Bound Ternary Copper(II) Cysteine Complex as Anticancer Agent Vietnam Malaysia International Chemical Congress (VMICC 2014) | 07 Nov 2014
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Miktoarm Star Polymers as a Nanocarrier for Drug Delivery: Synthesis, Characterisation, and In-vitro Drug Release Study The18th Malaysian International Chemical Congress (MICC) | 03 Nov 2014
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Subsidiary Ligand Effect on the Physical, Chemical and Biological Properties of A Series of Copper(II) Polypyridyl Complexes The18th Malaysian International Chemical Congress | 03 Nov 2014
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Binary and ternary copper(II) complexes of polypyridine and tyrosine: synthesis, characterization and comparative biological studies The18th Malaysian International Chemical Congress, PWTC | 03 Nov 2014
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Anticancer Property of Chiral Ternary Copper(II) Complexes The18th Malaysian International Chemical Congress | 03 Nov 2014
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AB2 Miktoarm Star Polymers [PLGA-(MPEG)2] as Nanocarriers for Drug Delivery The 5th International Conference on Nanotechnology: Fundamentals and application (CNFA '14) | 11 Aug 2014
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Encapsulation of Hydrophilic Drug into PLGA-PEG-FOL Nanoparticles by Nanoprecipitation” The 5th FIP Pharmaceutical Science World Congress (PSWC) | 13 Apr 2014
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DNA binding Recognition & Serum Albumin binding by Ternary Metal(II) Complexes the 12th International Symposium on Applied Bioinorganic Chemistry (ISABC12) | 03 Dec 2013
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A new Psyllium-based, natural and cost effective denture adhesive International Conference on Natural Products and Health 2013 (NPH 2013) | 05 Sep 2013
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Conceptualisation, Development and Implementation of Master of Science in Analytical and Pharmaceutical Chemistry (MAPC) IMEC 2013 | 14 Mar 2013
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Swelling property of bioceramics loaded PNIPAAm/ alginate hydrogel The 9th World Biomaterials Congress | 01 Jun 2012
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Effects of Microemulsion Preparation Conditions on Drug Encapsulation Efficiency of PLGA Nanoparticles The 4th Nanoscience and Nanotechnology Symposium (NSS 2011) | 23 Sep 2011
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Antibiotic Loaded Zirconia Bioceramics as Bone Substitute for Osteomyelitis International Society of Drug Delivery and Pharmaceutical Technology (APGI) 2nd Conference on “Innovation in drug Delivery: From Preformulation to Development through Innovative Evaluation Process | 03 Oct 2010
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Encapsulation of Hydrophilic Drug in PLGA Nanoparticles by the Single Emulsion Solvent Evaporation Method International Society of Drug Delivery and Pharmaceutical Technology (APGI) 2nd Conference on “Innovation in drug Delivery: From Preformulation to Development through Innovative Evaluation Process | 03 Oct 2010
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Study on the Fabrication of Low Cost Nickel/Gold Under Bump Metallization by Electroless Plating for Wafer Level Packaging Applications The 6th International Conference on Electronic Materials & Packaging (EMAP) | 05 Dec 2004
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Thermal Stability of Some Industrial Pretapes (High Temperature Engineering Plastics Tapes) The SEMICON Singapore 2002 Technical Symposium, Advanced Packaging Technologies I | 05 May 2002
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Preparation of Microcapsules Containing Naltrexone Hydrochloride using Poly(DL-Lactide-co-Glycolide) Copolymer as Encapsulation Materials. Malaysian Science and Technology Congress 1999 | 08 Nov 1999
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Synthesis and Characterization of Polyphenylquinoxaline Containing Pendant Phenylethynyl Substituents The International Conference on Advances in Materials and Processing Technologies, AMPT’98 | 24 Aug 1998

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Patents

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Method of Routing an Electrical Connection on a Semiconductor Device and Structure Therefor. US Patent No. 7138327 (2006) | 22 Sep 2005


Supervisions
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Gerald SAMBU KULWA | Master (Mixed Mode) | 29 May 2023 - 07 Mar 2024 Thesis: Functional properties and stability of resveratrol loaded Span60/Tween60 based niosomes with vitamin D as vesicular stabilizer
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Ms Ng Kar Wei | Undergraduate | 04 Jan 2022 - 28 Jun 2022 Thesis: In vitro antioxidative, anti-cholinesterase, and anti-alpha-amylase effects of gelatin-phenolic acid conjugates
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Nur Najihah Binti Salahuddin | Master (Mixed Mode) | 24 May 2021 Thesis: Synthesis, characterisation, antioxidant and alpha-glucosidase inhibitory activities of pectin-phenolic acid conjugate
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Mr Tan Oon Hock | Master (Research) | 06 Oct 2017 - 02 Mar 2021 Thesis: DEVELOPMENT AND VALIDATION OF LC-MS/MS METHOD FOR SIMULTANEOUS QUANTIFICATION OF VITAMIN E ISOFORMS IN HUMAN PLASMA
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Wong See Kiat | Master (Research) | 18 Jun 2014 - 11 Mar 2017 Thesis: SYNTHESIS, CHARACTERISATION AND EVALUATION OF STAR-BRANCHED FOLATE-CONJUGATED PLLA-PEG COPOLYMERS AS NANOCARRIERS FOR TARGETED DELIVERY OF DOXORUBICIN
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Ms Chong Yi e Kie | Master (Research) | 10 Jun 2014 - 30 Jul 2016 Thesis: MIKTOARM STAR POLYMERS AS A NANOCARRIER FOR DRUG DELIVERY: SYNTHESIS, CHARACTERISATION, AND IN-VITRO DRUG RELEASE STUDY
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Mr Ahmad Junaid | Master (Mixed Mode) | 18 Sep 2012 - 18 Jun 2014 Thesis: SYNTHESIS AND CHARACTERISATION OF NANOGOLD BOUND TERNARY COPPER(II) COMPLEX WITH CYSTEINE AND PHENANTHROLINE AS ANTICANCER AGENT

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