JESTIN CHELLIAN



Salutation
Dr

School/Centre
School of Pharmacy

Department
Life Sciences

Position
Senior Lecturer

Email
jestin_chellian@imu.edu.my



Education

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PhD in Medical and Health Sciences (Pharmacy), 2019 International Medical University (IMU)
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Master of Pharmacy (Pharmacology), 2007 The Tamil Nadu Dr. M.G.R. Medical University
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Bachelor of Pharmacy (Pharmacy), 2004 The Tamil Nadu Dr. M.G.R. Medical University
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Diploma in Pharmacy (Pharmacy), 1999 Directorate of Medical Education

Memberships

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Malaysian Diabetes Association Member 2012 - Present
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The Tamil Nadu State Pharmacy Council Registered Pharmacist 1999 - Present

Research Funding
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Evaluation of remyelinating property of alpha-tocopherol compared to fingolimod (FTY720), a known neuro-protective agent, in the cerebellum in cuprizone-induced animal model of multiple sclerosis Bachelor in Medical Sciences (Hons) | 2022-03-01 - 30 Jun 2022
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Comparison of the remyelinating property of alpha-tocopherol and tocotrienol in the cuprizone-induced animal model of multiple sclerosis Bachelor of Pharmacy (Hons) | 2021-05-27 - 25 Dec 2020
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In vitro and in vivo evaluation of acitretin-loaded lipid nanoparticles developed by quality-by-design approach IMU | 2020-06-01 - 01 Oct 2020
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Evaluation of Remyelinating Property of Alpha-Tocopherol Compared to FTY720 A Known Neuro-Protective Agent, In the Cuprizone-Induced Animal Model of Multiple Sclerois IMU | 2020-05-01 - 01 Sep 2020
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Evaluation of Anti-Atherosclerotic Activity of 6-Shogaol and Its Underlying Mechanism in High-Fat Diet Induced Atherosclerosis in Hamster IMU | 2019-07-01 - 01 Dec 2021
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Assessing the anti-inflammatory potential of Rhamnetin nanoparticles using immortalised bronchial epithelial cells as a therapeutic intervention for asthma IMU | 2019-06-01 - 01 Sep 2019
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Asessing the anti-Hyperglycemic Potential of the Crude Extracts of Caulerpa Racemosa in Low Dose Streptozotocin Induced Type 2 Diabetic Rats IMU | 2019-06-01 - 01 Sep 2019
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Evaluation of remyelinating property of alpha-tocopherol in the cuprizone-induced animal IMU | 2019-05-01 - 01 Oct 2019
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Assessing the Anti-Inflammatory and Cytotoxic Potential of a Chinese Traditional Herb Artemisia vulgaris in a Nano-Formulation IMU | 2018-07-18 - 18 Dec 2018
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Assessing the immune-modulatory potential of bio-potentiated beta-carotene in immune deficient male Sprague-Dawly rats IMU | 2018-06-01 - 01 Sep 2018

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Publications

Research Articles

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Bacterial Persister Cells and Development of Antibiotic Resistance in Chronic Infections: An Update BRITISH JOURNAL OF BIOMEDICAL SCIENCE 2024
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Hypoglycaemic Molecules for the Management of Diabetes Mellitus from Marine Sources DIABETES, METABOLIC SYNDROME AND OBESITY 2023
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Influence of Rutin and its Combination with Metformin on Vascular Functions in Type 1 Diabetes Scientific reports 2023
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Swietenine Alleviates Nonalcoholic Fatty Liver Disease in Diabetic Mice via Lipogenesis Inhibition and Antioxidant Mechanisms ANTIOXIDANTS 2023
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Comparing palm oil-derived tocotrienol-rich fraction with alpha-tocopherol in changes in locomotion and histological appearance in a cuprizone-induced animal model of multiple sclerosis INTERNATIONAL JOURNAL OF NUTRITION, PHARMACOLOGY, NEUROLOGICAL DISEASES 2023
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Exploring the role of antibiotics and steroids in managing respiratory diseases JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY 2022
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Quercetin and metformin synergistically reverse endothelial dysfunction in the isolated aorta of streptozotocin-nicotinamide-induced diabetic rats SCIENTIFIC REPORTS 2022
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Targeting the mitochondria in chronic respiratory diseases MITOCHONDRION 2022
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Locomotor and histological changes in a cuprizone-induced animal model of multiple sclerosis: comparison between alpha-tocopherol and fingolimod RESEARCH IN PHARMACEUTICAL SCIENCES 2022
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Autoantibodies and autoimmune disorders in SARS-CoV-2 infection: pathogenicity and immune regulation ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 2022
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Protein and peptide delivery to lungs by using advanced targeted drug delivery CHEMICO-BIOLOGICAL INTERACTIONS 2022
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Unravelling the molecular mechanisms underlying chronic respiratory diseases for the development of novel therapeutics via in vitro experimental models EUROPEAN JOURNAL OF PHARMACOLOGY 2022
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Nutritional profile, antioxidative and antihyperglycemic properties of Padina tetrastromatica from Tioman Island, Malaysia FOODS 2021
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Middle East Respiratory Syndrome (MERS) virus—pathophysiological axis and the current treatment strategies AAPS PHARMSCITECH 2021
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Anti‐inflammatory and anticancer activities of Naringenin‐loaded liquid crystalline nanoparticles in vitro JOURNAL OF FOOD BIOCHEMISTRY 2021
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Targeting neutrophils using novel drug delivery systems in chronic respiratory diseases DRUG DEVELOPMENT RESEARCH 2020
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Bioprospecting cultivated tropical green algae, Caulerpa racemosa (Forsskal) J. Agardh: a perspective on nutritional properties, antioxidative capacity and anti-diabetic potential FOODS 2020
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Molecular mechanisms of action of naringenin in chronic airway diseases EUROPEAN JOURNAL OF PHARMACOLOGY 2020
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Applications of nanocarriers as drug delivery vehicles for active phytoconstituents CURRENT PHARMACEUTICAL DESIGN 2020
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Evaluation of neuroprotective effects of alpha-tocopherol in cuprizone-induced demyelination model of multiple sclerosis RESEARCH IN PHARMACEUTICAL SCIENCES 2020
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Biological and therapeutic potential of the edible brown marine seaweed Padina australis and their pharmacological mechanisms JOURNAL OF TROPICAL BIOLOGY & CONSERVATION (JTBC) 2020
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Bioprospecting Cultivated Tropical Green Algae, Caulerpa racemosa (Forsskal) J. Agardh: A Perspective on Nutritional Properties, Antioxidative Capacity and Anti-Diabetic Potential. FOODS (BASEL, SWITZERLAND) 2020
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Green synthesis and antibacterial potential of Artemisia vulgaris extract in silver nanoparticles against wound bacteria SCIENTIFIC JOURNAL OF PHARMACY JIF 2020
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Antiretroviral agents in pre-exposure prophylaxis: emerging and advanced trends in HIV prevention JOURNAL OF PHARMACY AND PHARMACOLOGY 2019
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Formulation and characterization of glibenclamide and quercetin-loaded chitosan nanogels targeting skin permeation THERAPEUTIC DELIVERY 2019
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Interactions between microbiome and lungs: Paving new paths for microbiome based bio-engineered drug delivery systems in chronic respiratory diseases CHEMICO-BIOLOGICAL INTERACTIONS 2019
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Current status on immunological therapies for type 1 diabetes mellitus CURRENT DIABETES REPORTS 2019
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Therapeutic potential of Artemisia vulgaris: An insight into underlying immunological mechanisms JOURNAL OF ENVIRONMENTAL PATHOLOGY, TOXICOLOGY AND ONCOLOGY 2019
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Gene therapy and type 1 diabetes mellitus BIOMEDICINE & PHARMACOTHERAPY 2018
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The role of bevacizumab on tumour angiogenesis and in the management of gynaecological cancers: A review BIOMEDICINE & PHARMACOTHERAPY 2018
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Nanogels linked with chitosan: a perspective MINERVA MEDICA 2018
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Transdermal delivery of tolterodine tartrate for overactive bladder treatment: In vitro, and in vivo evaluation ACTA PHARMACEUTICA 2017
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Vesicular systems containing curcumin and their applications in respiratory disorders–a mini review PHARMACEUTICAL NANOTECHNOLOGY 2017
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Oral insulin: current status, challenges, and future perspectives JOURNAL OF ENVIRONMENTAL PATHOLOGY, TOXICOLOGY AND ONCOLOGY 2017
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The role of pazopanib on tumour angiogenesis and in the management of cancers: A review BIOMEDICINE & PHARMACOTHERAPY 2017
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Transdermal delivery of oxybutynin chloride proniosomal gels for the treatment of overactive bladder DRUG DELIVERY 2016
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Tolterodine tartrate proniosomal gel transdermal delivery for overactive bladder PHARMACEUTICS 2016
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The protective action of the aqueous extract of Auricularia polytricha in paracetamol induced hepatotoxicity in rats RECENT PATENTS ON DRUG DELIVERY & FORMULATION 2016
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Development and evaluation of nanostructured lipid carrier-based hydrogel for topical delivery of 5-fluorouracil INTERNATIONAL JOURNAL OF NANOMEDICINE 2016
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CYP 2D6* 4 polymorphism and interindividual response variation to metoprolol instage 1 hypertensive patients: no association in a rural Indian population? TURKISH JOURNAL OF MEDICAL SCIENCES 2015
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Preliminary studies on antimicrobial activity of Swietenia macrophylla leaf extract INT. J. PHARM. SCI. REV. RES 2012
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Resazurin assay for determination of antimicrobial activity in Dillenia ovata LEVERAGING ON MICROBIAL DIVERSITY FOR A SUSTAINABLE FUTURE: PROCEEDINGS OF THE INTERNATIONAL CONGRESS OF THE MALAYSIAN SOCIETY FOR MICROBIOLOGY 2011 2011

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Other Publications

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Emerging Landscape and Novel Approaches in Vaccine Development for COVID-19: An Update Webinar as a Resource Person on the Topic | 23 Jul 2021
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Two-day national virtual seminar on “Repurpose drugs: New strategies for drug development" Two-day national virtual seminar on “Repurpose drugs: New strategies for drug development" | 10 Jun 2021