WONG LAI CHUN
Salutation
Dr
School/Centre
School of Pharmacy
Department
Pharmaceutical Chemistry
Position
Senior Lecturer
Email
Education
a
PhD (Chemistry), 2010
Northumbria University
a
MRes. Chemical Biology (Chemistry), 2006
Northumbria University
a
B.Sc. Chemistry (Hons) (Chemistry), 2005
University Malaya
Memberships
a
Royal Society of Chemistry
Member Communities Board
2021 - Present
a
Royal Society of Chemistry
Secretary of RSC Malaysia Local Section
2017 - Present
a
Royal Society of Chemistry
Member
2009 - Present
Research Funding
a
Preparation, physicochemical properties and antibacterial activity of gallium-crosslinked carboxymethyl cellulose scaffolds loaded with quercetin, curcumin and/or rutin
IMU Internal Research Grant | 17 Mar 2025 - 31 Aug 2025
a
Preparation, physicochemical properties and antibacterial activity of alginate scaffolds loaded with quercetin and/or rutin
IMU Internal Research Grant | 21 Oct 2024 - 20 Apr 2025
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Nanoemulsion-Based Multi-Responsive In-Situ Gel for Ophthalmic Delivery of Lutein and Zeaxanthin: Formulation, Release, and Biocompatibility.
IMU Internal Research Grant | 22 Aug 2024 - 31 Dec 2026
a
Fabrication, physicochemical properties, antibacterial evaluation, and in vitro healing assessment of curcumin, quercetin and metal organic framework-loaded scaffolds for bioactive wound dressings
IMU Internal Research Grant | 15 Jul 2024 - 30 Jun 2026
a
Fabrication, antibacterial activity and cytocompatibility of alginate-carboxymethyl cellulose hydrogel loaded with bioactive glass and alizarin for skin tissue regeneration
IMU Internal Research Grant | 01 Jul 2024 - 30 Jun 2025
a
Biopolymer-based hydrogel scaffolds enriched with alizarin and copper oxide nanoparticles for skin wound dressing: Formulation, physicochemical properties, and antibacterial activity
IMU Internal Research Grant | 02 May 2024 - 30 Apr 2025
a
Biomimetic quercetin-curcumin loaded 3D biopolymeric scaffolds for skin tissue regeneration and repair: Cytocompatibility, antibacterial and antioxidant studies
IMU Internal Research Grant | 21 Mar 2024 - 31 Jan 2025
a
Development and Validation of a Stability-Indicating Reverse Phase-Liquid Chromatography Assay for the Determination of Polymeric Surfactants in Natural Rubber Latex
IMU Internal Research Grant | 18 Mar 2024 - 25 May 2024
a
Physicochemical properties and antibacterial activity of cellulose-based scaffolds loaded with curcumin/metal-organic framework particles
IMU Internal Research Grant | 18 Mar 2024 - 31 Jul 2024
a
Synthesis and Evaluation of Shogaols as Potential Antibacterial Agents Against Multidrug-Resistant Pathogens
IMU Internal Research Grant | 01 Mar 2024 - 30 Oct 2024
a
Development and Validation of RP-HPLC Dissolution Method for Dapagliflozin and Metformin Hydrochloride in Extended-Release Tablets
IMU Internal Research Grant | 16 Nov 2023 - 31 Mar 2025
a
Elucidating the role of nanoemulsion based multi-stimuli responsive in-situ gel for opthalmic delivery of lutein and zeaxanthin.
FRGS 2023 | 01 Oct 2023 - 30 Sep 2025
a
Preparation, physicochemical and antibacterial properties of chitosan-gelatin scaffolds encapsulated with bioactive agents
IMU Internal Research Grant | 12 Jun 2023 - 31 Dec 2023
a
Fabrication, physicochemical and biological properties of polysaccharide-protein hydrogels loaded with curcumin-zinc oxide nanoparticles for wound dressing applications
IMU Internal Research Grant | 01 Jun 2023 - 31 Oct 2023
a
The synthesis of shogaols and investigation of their antimicrobial activity
IMU Internal Research Grant | 18 May 2023 - 01 Feb 2024
a
Ruthenium complexes for antibacterial and anticancer photodynamic therapy
IMU Internal Research Grant | 01 May 2023 - 31 Mar 2024
a
Fabrication and antibacterial property of curcumin-loaded metal-organic frameworks impregnated chitosan-gelatin hydrogel for wound dressing applications
IMU Internal Research Grant | 28 Mar 2023 - 30 Jun 2023
a
Development and validation of a RP-HPLC method to determine caffeine and trigonelline content in commercial coffee samples of Malaysian market.
IMU Internal Research Grant | 27 Mar 2023 - 03 Jun 2023
a
Curcumin functionalised copper/zinc-based metal-organic frameworks impregnated chitosan-gelatin nanofiber membrane for wound dressing and drug delivery applications
IMU Internal Research Grant | 01 Dec 2022 - 30 Nov 2023
a
Semi-synthesis of shogaol analogues and evaluation of their anti-neuroinflammatory activities
IMU Internal Research Grant | 01 May 2021 - 30 Jun 2023
Publications
Research Articles
a
Comparison of vegetable oils on the uptake of lutein and zeaxanthin by ARPE-19 cells
INTERNATIONAL JOURNAL OF OPHTHALMOLOGY 2023
a
Analytical Validation of a Reversed-Phase Ion Pairing HPLC-DAD Method for the Simultaneous Determination of Anthropogenic Pollutants
METHODS AND OBJECTS OF CHEMICAL ANALYSIS 2023
a
Coffee consumption revealed sex differences in host endogenous metabolism and gut microbiota in healthy adults
JOURNAL OF FOOD BIOCHEMISTRY 2020
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The synthesis of trifluoromethylated N-nitroaryl-2-amino-1, 3-dichloropropane derivatives and their evaluation as potential anti-cancer agents
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2020
a
Development and validation of a script concordance test (SCT) to evaluate ethical reasoning ability among first and fifth year students in a medical school
JOURNAL OF ACADEMIC ETHICS 2019
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Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells
CUTANEOUS AND OCULAR TOXICOLOGY 2018
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Antioxidants and cactus extract enhances the sun protection factor of octocrylene and oxybenzone solution
Malaysian Journal of Fundamental and Applied Sciences 2018
a
DEVELOPMENT AND VALIDATION OF A REVERSE PHASE-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-ULTRAVIOLET METHOD FOR SIMULTANEOUS DETECTION OF CAFFEINE AND PHENOLPHTHALEIN IN WEIGHT REDUCING SUPPLEMENTS
MALAYSIAN JOURNAL OF ANALYTICAL SCIENCES 2017
a
Studies relating to the synthesis, enzymatic reduction and cytotoxicity of a series of nitroaromatic prodrugs
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2016
a
Convenient Synthesis of Highly Substituted Imidazole Derivatives
SYNTHETIC COMMUNICATIONS 2013
a
The Synthesis of Some Novel 1, 2‐Dihydroisoquinoline Derivatives
JOURNAL OF HETEROCYCLIC CHEMISTRY 2013
a
The synthesis of 2-nitroaryl-1, 2, 3, 4-tetrahydroisoquinolines, nitro-substituted 5, 6-dihydrobenzimidazo [2, 1-a] isoquinoline N-oxides and related heterocycles as potential bioreducible substrates for the enzymes NAD (P) H: quinone oxidoreductase 1 and E. coli nitroreductase
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2011
a
An unexpected ring contraction of two nitroaryl pro-drugs: conversion of N-(nitroaryl)-3-chloropiperidine derivatives into N-(nitroaryl)-2-chloromethylpyrrolidines
TETRAHEDRON LETTERS 2010
Other Publications
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INTEGRATING COLLABORATIVE ONLINE PLATFORM INTO THE FLIPPED CLASSROOM
International Medical University Learning Resources Festival 2023 | 06 Nov 2023
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The synthesis of shogaols and investigation of their antibacterial activity
4th Commonwealth Chemistry Posters | 04 Oct 2023
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The Use of Virtual Online Debate in the Classroom to Teach Ethics
International Medical University Learning Resources Festival 2022 | 14 Nov 2022
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The 9th International Postgraduate Conference on Pharmaceutical Sciences 2022
(IPoPs 2022) | 23 Jun 2022
a
Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells
7th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS2020) | 28 Feb 2020
a
In vitro evaluation of the anticancer properties of the N-((1S,2S)-1,3-dichloro-1-phenylpropan-2-yl)aniline derivative (RB8)
12th Malaysian Pharmaceutical Society Pharmacy Scientific Conference | 13 Nov 2015
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In vitro evaluation of the anticancer properties of the N-((1R,2R-1,3-dichloro-1-phenylpropan-2-Yl)aniline Derivative (RB9)
12th Malaysian Pharmaceutical Society Pharmacy Scientific Conference | 13 Nov 2015
a
In vitro evaluation of the anti-cancer properties of the (1S,2S)-1-phenyl-2-(phenylamino)propane-1,3-diol derivative (RB4)
12th Malaysian Pharmaceutical Society Pharmacy Scientific Conference | 13 Nov 2015
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In Vitro Evaluation of the Anti-cancer Properties of the (1R,2R)-1-phenyl-2-(phenylamino)propane-1,3-diol Derivative (RB5)
12th Malaysian Pharmaceutical Society Pharmacy Scientific Conference | 13 Nov 2015
a
Development of a script concordance test to assess ethical reasoning ability (SCT-ERA): A preliminary study
Association for Medical Education in Europe (AMEE) | 30 Aug 2014
Supervisions
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DIPESH PATEL A/L SURESHCHANDRA | Undergraduate | 18 Mar 2024
Thesis: Development and Validation of a Stability-Indicating Reverse Phase-Liquid Chromatography Assay for the Determination of Polymeric Surfactants in Natural Rubber Latex
a
Soh Yuin Yin | Undergraduate | 18 Mar 2024
Thesis: Development and Validation of a Stability-Indicating Reverse Phase-Liquid Chromatography Assay for the Determination of Polymeric Surfactants in Natural Rubber Latex
a
FONG RUI QI RICHELLE | Undergraduate | 18 Mar 2024
Thesis: Development and Validation of a Stability-Indicating Reverse Phase-Liquid Chromatography Assay for the Determination of Polymeric Surfactants in Natural Rubber Latex
a
Lim Siang Han | Undergraduate | 01 Mar 2024
Thesis: Synthesis and Evaluation of 7-shogaol as Potential Antibacterial Agents Against Multidrug-Resistant Pathogens
a
Gan Sin Yee | Undergraduate | 01 Mar 2024
Thesis: Synthesis and Evaluation of 8-Shogaol as Potential Antibacterial Agents Against Multidrug-Resistant Pathogens
a
Ong Xin Ying | Undergraduate | 01 Mar 2024
Thesis: Synthesis and Evaluation of 9-Shogaol as Potential Antibacterial Agents Against Multidrug-Resistant Pathogens
a
Chew Wan Yi | Undergraduate | 01 Mar 2024
Thesis: Synthesis and Evaluation of 10-Shogaol as Potential Antibacterial Agents Against Multidrug-Resistant Pathogens
a
NICHOLAS PEH HIAN TUNG | Master (Research) | 01 Jan 2024
Thesis: Stimuli-responsive In-situ gel nanoemulsion for ophthalmic delivery of lutein and zeaxanthin
a
Lee Ching Yee | Master (Mixed Mode) | 16 Nov 2023
Thesis: Development and Validation of RP-HPLC Dissolution Method for Dapagliflozin and Metformin Hydrochloride in Extended-Release Tablets
a
HASEEB AHMED SAYEED KHADAS | Master (Mixed Mode) | 18 May 2023
Thesis: The synthesis of shogaols and investigation of their antimicrobial activity
a
Lee Ke Hui | Master (Mixed Mode) | 01 May 2023
Thesis: Ruthenium complexes for antibacterial and anticancer photodynamic therapy
a
Lee Yen Mae | Undergraduate | 27 Mar 2023 - 03 Jun 2023
Thesis: Development and validation of a RP-HPLC method to determine caffeine and trigonelline content in commercial coffee samples of Malaysian market.
a
Cherlyn Cheng Chen Xi | Undergraduate | 27 Mar 2023 - 03 Jun 2023
Thesis: Development and validation of a RP-HPLC method to determine caffeine and trigonelline content in commercial coffee samples of Malaysian market.