ABDUL AZIZ BIN BABA



Salutation
Professor

School/Centre
School of Medicine

Department
Internal Medicine

Appointment
Senior Advisor, International Office

Position
Professor


Professional Network


Education

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FRCP (Internal Medicine), 1995 Royal College of Physicians, Edinburgh
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MRCP (UK) (Internal Medicine), 1986 Royal College of Physicians, Edinburgh
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MRCP (Ireland) (Internal Medicine), 1986 Royal College of Physicians, Ireland
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MBBS (Medicine), 1979 University of Melbourne

Memberships

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Malaysian Society of Haematology | National | Member

Publications

Research Articles

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Elucidating the Mechanisms of Combination Therapy Using Palm Vitamin E And Commercial Anti Leukemic Drug (Cytarabine) In Cell-Based Models of Acute Myeloid Leukaemia. MALAYSIAN JOURNAL OF MEDICINE & HEALTH SCIENCES | 2024
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Differentially Expressed Proteins in Transfusion-Dependent Thalassemia (TDT) and Their Role in Tdt Disease Severity BLOOD | 2022
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Investing in scholarship for health professions education: Learning from the past to move into the future MEDICAL TEACHER | 2021
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A link between long non-coding RNA (lncRNA) and thalassaemia: A review THE MALAYSIAN JOURNAL OF PATHOLOGY | 2020
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A novel method to identify autoantibodies against putative target proteins in serum from beta-thalassemia major: a pilot study BIOMEDICINES | 2020
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Aberrant DNA Methylation of SOCS1 Gene is Not Associated with Resistance to Imatinib Mesylate among Chronic Myeloid Leukemia Patients CARDIOVASCULAR & HAEMATOLOGICAL DISORDERS-DRUG TARGETS (FORMERLY CURRENT DRUG TARGETS-CARDIOVASCULAR & HEMATOLOGICAL DISORDERS) | 2018
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Genetic variations in influx transporter gene SLC22A1 are associated with clinical responses to imatinib mesylate among Malaysian chronic myeloid leukaemia patients JOURNAL OF GENETICS | 2018
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Aberrant DNA methylation at HOXA4 and HOXA5 genes are associated with resistance to imatinib mesylate among chronic myeloid leukemia patients CANCER REPORTS | 2018
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Pharmacogenetics and the treatment of chronic myeloid leukemia: how relevant clinically? An update PHARMACOGENOMICS | 2018
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Association of GSTM1, GSTT1 and GSTP1 Ile105Val polymorphisms with clinical response to imatinib mesylate treatment among Malaysian chronic myeloid leukaemia patients JOURNAL OF GENETICS | 2017
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Molecular genetic and epigenetic markers of Imatinib resistance in chronic myeloid leukemia patients ANNALS OF ONCOLOGY | 2016
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Beta-thalassemia and molecular chaperones BLOOD CELLS, MOLECULES, AND DISEASES | 2015
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P0172clinical relevance of a pharmacogenetic approach using multiple transporter genes to predict response and resistance to imatinib therapy in malaysian patients with chronic myeloid leukaemia EUROPEAN JOURNAL OF CANCER | 2015
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Characterizing PML/RARα Isoforms of Acute Promyelocytic Leukemia (APL) in Malay patients. BANGLADESH JOURNAL OF MEDICAL SCIENCE | 2014
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P0223 CYP3A4∗ 18 and CYP3A5∗ 3 gene polymorphisms and imatinib resistance in Malaysian patients with chronic myeloid leukaemia EUROPEAN JOURNAL OF CANCER | 2014
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A review of AML classification: a single institution experience in a developing country JOURNAL OF HEMATOPATHOLOGY | 2014
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The differential metabolite profiles of acute lymphoblastic leukaemic patients treated with 6-mercaptopurine using untargeted metabolomics approach CLINICAL BIOCHEMISTRY | 2014
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Clinical impact of ABCC 1 and ABCC 2 genotypes and haplotypes in mediating imatinib resistance among chronic myeloid leukaemia patients JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 2014
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Association of genotypes and haplotypes of multi-drug transporter genes ABCB1 and ABCG2 with clinical response to imatinib mesylate in chronic myeloid leukemia patients BIOMEDICINE & PHARMACOTHERAPY | 2014
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BCR-ABL kinase domain mutations, including 2 novel mutations in imatinib resistant Malaysian chronic myeloid leukemia patients—Frequency and clinical outcome LEUKEMIA RESEARCH | 2014
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Predictive Molecular Markers of Imatinib Resistance and Prognosis in Chronic Myeloid Leukemia Patients ANNALS OF ONCOLOGY | 2013
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HOXA4 gene promoter hypermethylation as an epigenetic mechanism mediating resistance to imatinib mesylate in chronic myeloid leukemia patients BIOMED RESEARCH INTERNATIONAL | 2013
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Talactoferrin alfa versus placebo in patients with refractory advanced non-small-cell lung cancer (FORTIS-M trial) ANNALS OF ONCOLOGY | 2013
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Prevalence and associated factors of stress, anxiety and depression among prospective medical students ASIAN JOURNAL OF PSYCHIATRY | 2013
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Evaluating the Impact of MRP1 and MRP2 Polymorphisms on the Pharmacoresistance to Imatinib Treatment Among CML Patients ANNALS OF ONCOLOGY | 2013
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Psychological distress of first year medical students who underwent two different admission processes during a stressful period SAINS MALAYSIANA | 2013
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Research Article HOXA4 Gene Promoter Hypermethylation as an Epigenetic Mechanism Mediating Resistance to Imatinib Mesylate in Chronic Myeloid Leukemia Patients N/A | 2013
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The impact of medical education on psychological health of students: a cohort study PSYCHOLOGY, HEALTH & MEDICINE | 2013
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Polymorphism of ITPA 94C> A and risk of adverse effects among patients with acute lymphoblastic leukaemia treated with 6‐mercaptopurine JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 2012
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Influence of CYP1A2, CYP3A5 and CYP2C19 Polymorphisms on Imatinib Mesylate Drug Responses in Three Major Asian Ethnic Groups and Variation of IM and Active Metabolite (M1) Trough Level Among Chronic Myeloid Leukemia Patients ANNALS OF ONCOLOGY | 2012
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P-1408-Prevalence and associated factors of stress, anxiety and depression among entering medical students EUROPEAN PSYCHIATRY | 2012
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Influence of ABCB1 C3435T and ABCG2 C421A gene polymorphisms in response to imatinib mesylate in chronic myeloid leukemia patients INT J ENVIRON SCI DEV | 2012
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Contribution of BCR-ABL kinase domain mutations to imatinib mesylate resistance in Philadelphia chromosome positive Malaysian chronic myeloid leukemia patients HEMATOLOGY REPORTS | 2012
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A study of psychological distress in two cohorts of first-year medical students that underwent different admission selection processes THE MALAYSIAN JOURNAL OF MEDICAL SCIENCES: MJMS | 2012
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FP04-2 Medical Students' Mental Health Status at the Beginning of the First Year Study of Two Different Selection Processes ASIAN JOURNAL OF PSYCHIATRY | 2011
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Low incidence of FLT3 gene mutation among Malay patients with Acute Myeloid Leukemia: A preliminary study AS PAC J MOL BIOL BIOTECHNOL | 2011
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Medical student selection process and its pre-admission scores association with the new students’ academic performance in Universiti Sains Malaysia INTERNATIONAL MEDICAL JOURNAL | 2011
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A comparison between infrared tympanic thermometry, oral and axilla with rectal thermometry in neutropenic adults EUROPEAN JOURNAL OF ONCOLOGY NURSING | 2009
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One-step multiplex RT-PCR for detection of BCR/ABL gene in Malay patients with chronic myeloid leukaemia ASIA PACIFIC JOURNAL OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY | 2008
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CHRONIC MYELOID LEUKAEMIA IN HUSM IN THE ERA OF TARGETED THERAPY. MALAYSIAN JOURNAL OF MEDICAL SCIENCES | 2007
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Assessment of knowledge, attitude and exposure to oncology and palliative care in undergraduate medical students MED J MALAYSIA | 2004
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8th. National Conference on Medical Sciences:“Medicine in the Genomic Era” THE MALAYSIAN JOURNAL OF MEDICAL SCIENCES: MJMS | 2003
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Adjuvant treatment in colorectal cancer. Experience from a referral center in eastern peninsular Malaysia. TROPICAL GASTROENTEROLOGY: OFFICIAL JOURNAL OF THE DIGESTIVE DISEASES FOUNDATION | 2002
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The absence of factor V Leiden mutation in Malays with recurrent spontaneous abortions AUSTRALIAN AND NEW ZEALAND JOURNAL OF OBSTETRICS AND GYNAECOLOGY | 2002
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Detection of Clonal Lymphoid Population by IgH Chain Gene Rearrangement Analysis in Malignant Lymphomas at Universiti Sains Malaysia Hospital ASIA PACIFIC JOURNAL OF MOLECULAR BIOLOGY & BIOTECHNOLOGY | 2002
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1st Asean Conference on Medical Sciences18th–21th May 2001Held at the Renaissance Hotel Kota Bharu, Kelantan, Malaysia. THE MALAYSIAN JOURNAL OF MEDICAL SCIENCES: MJMS | 2001
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Clinical significance of p53 protein expression in Non-Hodgkin's lymphoma among Malaysian patients EUROPEAN JOURNAL OF CANCER | 1999
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Differential transcriptional regulation of the human gene for the M1 subunit of ribonucleotide reductase by p53 EUROPEAN JOURNAL OF CANCER | 1997
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Cumulative contents BIOMEMBRANES | 1996
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Adult idiopathic thrombocytopenic purpura without the option of splenectomy MED. J. MALAYS | 1995

Other Publications

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EXPLORING THE MECHANISMS UNDERLYING RESPONSE VARIATION TO IMATINIB MESYLATE TREATMENT AMONG MALAYSIAN CHRONIC MYELOID LEUKEMIA PATIENTS-A MOLECULAR, EPIGENETIC AND PHARMACOGENETIC APPROACH HAEMATOLOGICA | 01 Jan 2012
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Determination of imatinib mesylate (Gleevec (TM)) and CGP 74588 in serum samples using ultra-high performance liquid chromatography THERAPEUTIC DRUG MONITORING | 01 Jan 2011
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MULTIPLE PATHS TO DRUG RESISTANCE PHENOTYPE IN CHRONIC MYELOID LEUKEMIA PATIENTS UNDERGOING IMATINIB MESYLATE TREATMENT ANTICANCER RESEARCH | 01 Jan 2008