YAM WAI KEAT
Salutation
Dr
School/Centre
School of Business and Technology
Department
Digital Health and Health Informatics (DHHI)
Appointment
Associate Dean, Research & External Engagement
Position
Senior Lecturer
Email
Education
a
Doctor of Philosophy (PhD) (Structural Bioinformatics), 2009
Universiti Sains Malaysia
a
Bachelor of Science (Hons) (Bioinformatics) (Bioinformatics), 2004
Universiti Malaya
Memberships
a
International Society for Computational Biology (ISCB)
Co-Chair Education Committee
2024 - Present
a
Asia eHealth Information Network (AeHIN)
Member
2023 - Present
a
Global Organisation for Bioinformatics Learning, Education & Training (GOBLET)
Executive Board Member
2023 - Present
a
International Society for Computational Biology (ISCB)
Member
2022 - 2023
a
Asia Pacific Bioinformatics Network (APBioNET)
Committee
2018 - Present
a
Malaysian Society of Bioinformatics and Computational Biology (MaSBiC)
Committee
2018 - 2023
Research Funding
a
Examining the Relationship Between Social Determinants of Health and Healthcare Utilisation Patterns Through Elderly Population Dataset
IMU Internal Research Grant | 28 May 2024 - 31 Dec 2024
a
Molecular Dynamics Simulation of Hyperphosphorylated Tau Protein with Potential Ligands from Drug Repurposing with Paliperidone, Asenapine and Pentazocine.
IMU Internal Research Grant | 28 May 2024 - 31 Dec 2024
a
2D ligand-based similarity searching and structure-based virtual screening for identification of potential Porphyromonas gingivalis peptidylarginine deiminase inhibitors as rheumatoid arthritis pharmacotherapy
IMU Internal Research Grant | 08 Apr 2024 - 07 Feb 2025
a
Molecular Dynamics Simulation of Hyperphosphorylated Tau Protein With Potential Ligands From Drug Repurposing in Alzheimer’s Disease
IMU Internal Research Grant | 11 Mar 2023 - 31 Dec 2023
a
Evaluation of the use of electronic health (eHealth) applications by Malaysian community pharmacists - A survey study
IMU Internal Research Grant | 11 Sep 2022 - 29 Feb 2024
a
Electronic health (eHealth): Knowledge, attitudes, and practices among Malaysian community pharmacists - A survey study
IMU Internal Research Grant | 11 Sep 2022 - 30 Jun 2024
a
Computational Drug Repurposing for Hyperphosphorylated Tau Protein in Alzheimer’s Disease Using Molecular Dynamics Simulation.
IMU Grant | 01 Apr 2022 - 01 Sep 2022
a
Data Analytics on Trend of C-reactive Protein (CRP) Level and Its Correlation with Other Clinical Parameters in Describing Disease Progression of Mild COVID-19 Patients.
IMU Grant | 01 Apr 2022 - 30 Sep 2022
a
Development of AI-powered Clinical Decision-Support System based on Big-Data Analytics for Molecular Genetic Diagnosis
Prototype Research Grant Scheme | 01 Jan 2019 - 01 Jan 2022
a
Targeting the tumor-specific spliceosome through in silico virtual screening for discovery of new SF3B1 small molecule inhibitors.
Fundamental Research Grant Scheme | 01 Jan 2015 - 01 Jan 2017
a
Identification of Self-Renewal and Developmental Pathways in Nasopharyngeal Carcinoma Cancer Stem Cells Through Gene and MicroRNA Expression Profiling and Functional Studies.
Fundamental Research Grant Scheme | 01 Jan 2013 - 01 Jan 2016
a
Development of glycyrrhizic acid analogues to combat type 2 diabetes mellitus
Exploratory Research Grant Scheme (ERGS) | 01 Jan 2012 - 01 Jan 2015
a
Characterising host-parasite metabolic interaction of Toxoplasma gondii infection in murine model: A system biology approach.
E-Science Fund | 01 Jan 2012 - 01 Jan 2014
Publications
Research Articles
a
Book of abstracts of the 21st international conference on bioinformatics (InCoB)
F1000RESEARCH 2023
a
Repurposing FDA-approved drugs as HIV-1 integrase inhibitors: An in silico investigation
JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS 2022
a
In-silico discovery of inhibitors against human papillomavirus E1 protein
JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS 2022
a
Life Sciences 4.0
MEDICAL JOURNAL OF MALAYSIA 2022
a
Selected articles from the 20th Asia Pacific Bioinformatics Conference (APBC 2022): bioinformatics. Edited by Lam Su Datt, Yam Wai Keat, M. Firdaus Raih and Phoebe Chen.
BMC BIOINFORMATICS 2022
a
Sub-structure-based screening and molecular docking studies of potential enteroviruses inhibitors
COMPUTATIONAL BIOLOGY AND CHEMISTRY 2021
a
Regression QSAR Models for Predicting HIV-1 Integrase Inhibitors
BIORXIV 2021
a
Identification and characterization of the VPE gene family and its expression in response to Fusarium oxysporum infection in Musa acuminata
ASIAN JOURNAL OF MEDICINE AND BIOMEDICINE 2018
a
Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1)
SCIENTIFIC REPORTS 2017
a
Targeting heat shock proteins 60 and 70 of toxoplasma gondii as a potential drug target: In silico approach
INTERDISCIPLINARY SCIENCES: COMPUTATIONAL LIFE SCIENCES 2016
a
Systems biology analyses of the dynamic host response to Toxoplasma gondii infection in a murine model
PARASITOLOGY OPEN 2016
a
Acclimatisation-induced stress influenced host metabolic and gut microbial composition change
MOLECULAR BIOSYSTEMS 2015
a
Interaction of ganoderic acid on HIV related target: molecular docking studies
BIOINFORMATION 2011
a
Molecular insights into 14-membered macrolides using the MM-PBSA method
JOURNAL OF CHEMICAL INFORMATION AND MODELING 2009
a
Refinement of a low-resolution crystal structure to better understand erythromycin interactions on large ribosomal subunit
JOURNAL OF BIOMOLECULAR STRUCTURE AND DYNAMICS 2008
Other Publications
a
Skillsets Transferability in Bioinformatics: Developing Essential Skills for Future Scientists.
2nd International Colloquium on Bioinformatics Learning (iCOBLET2024) | 20 Nov 2024
a
Formulation of a Core Bioinformatics Module in Life Science Postgraduate Programme: A Practical Example at IMU University
1st Asia & Pacific Bioinformatics Joint Conference 2024 (APBJC2024) | 22 Oct 2024
a
Molecular Dynamics Simulation of Hyperphosphorylated Tau Protein with Potential Ligands from Drug Repurposing.
3rd Asian Student Council Symposium (ASCS2024) | 22 Oct 2024
a
Exploring the ISCB Competency Framework Version 3.0
1st Asia & Pacific Bioinformatics Joint Conference 2024 (APBJC2024) | 22 Oct 2024
a
Bioinformatics Landscape in Malaysia
1st Asia & Pacific Bioinformatics Joint Conference 2024 (APBJC2024) | 22 Oct 2024
a
What’s next in my Bioinformatics journey?
Malaysian Youth Bioinformatics Symposium (MYBS) 6.0 | 17 Aug 2024
a
Protein Homology Modelling
Structural Bioinformatics Workshop - From DNA Mutations To 3D Protein Structure | 17 Jul 2024
a
Talk Show: A Day as a Bioinformatician
Indonesian Medical Education and Research Institute (IMERI) | 03 Jul 2024
a
Protein-Protein Interaction or Drug-Protein Interaction
Faculty Mobility Program | 29 Apr 2024
a
Multiomics Approach for Drug Discovery and Development
Faculty Mobility Program | 28 Mar 2024
a
Machine Learning or AI Application for Drug Discovery and Development
Faculty Mobility Program | 28 Feb 2024
a
Harmonizing Diversity: Uniting Disciplines in Bioinformatics.
2nd Asian Student Council Symposium (ASCS2023). | 25 Nov 2023
a
Navigating the Evolving Landscape: Challenges and Opportunities for Bioinformatics Education in the 21st Century
International Conference on Bioinformatics 2023 (InCoB2023) | 15 Nov 2023
a
Molecular Dynamics Simulation of Hyperphosphorylated Tau Protein with Potential Ligands From Drug Repurposing In Alzheimer’s Disease. International Conference on Bioinformatics 2023
International Conference on Bioinformatics 2023 (InCoB2023) | 12 Nov 2023
a
Education and Training in Computational Structural Biology
Malaysia Structural Biology Symposium 2023 (MSBS) | 05 Sep 2023
a
Bioinformatics Education, Learning & Training.
Bioinformatics Open Day | 29 Mar 2023
a
Repurposing Drugs for Inhibition of Hyperphosphorylated Tau Protein in Alzheimer’s Disease: Structural Bioinformatics Studies.
International Conference on Bioinformatics 2022 | 21 Nov 2022
a
Molecular Dynamics Simulation.
MD Workshop | 09 Nov 2022
a
Bioinformatics Education & Training Effort at Asia Pacific.
ISCBacademy by International Society for Computational Biology (ISCB) | 25 Oct 2022
a
Life Sciences 4.0
The 15th National Conference for Clinical Research (NCCR) 2022: Data to Decisions | 18 Oct 2022
a
Digital Health: A Multi-sectorial Effort in a High Growth Digital Health Industry (Panel Discussion)
IMU Digital Health Dialogue | 20 Aug 2022
a
Digital Health.
FB Live Engagement Session: IMU Science Discovery Challenge (SDC) | 16 Jul 2022
a
Computational Biomedical Science. Dept of Biomedical Science
Universiti Malaya Biomedical Programme | 07 Jun 2022
a
Comparative Molecular Dynamics Simulation Analysis on Wild Type and Mutant Type I1585M of USP9X Catalytic Domain.
Asia Pacific Bioinformatics Conference 2022 (APBC2022) | 26 Apr 2022
a
What Can We Learn From Computational Biology/Chemistry Works in Drug Discovery?
Pharmaceutical Analysis and Medicinal Chemistry Seminar Webinar | 18 Mar 2022
Medias
a
Exchange of Experience for Training Operations During a Three Day Working Meeting.
RItrainPlus News & Events | 05 Sep 2023
a
Collaboration with the Kaduna State University.
APBioNET | 01 Sep 2023
a
Bioinformatics Education Summit 2023
APBioNET | 01 Sep 2023
a
Bioinformatics Education Summit 2022.
Asia Pacific Bioinformatics Network (APBioNET) | 01 Dec 2022
a
Bioinformatics Education Special Track @ InCoB.
Global Organisation for Bioinformatics Learning, Education and Training (GOBLET) | 01 Oct 2022
a
2021 Bioinformatics Education Summit - Summary & Outlook
Global Organisation for Bioinformatics Learning, Education and Training (GOBLET) | 01 Feb 2022
Supervisions
a
Madeline Chee | Undergraduate | 01 Aug 2024 - 31 Dec 2024
Thesis: Development of Data Dashboard to Visualise Mobile Clinic Data.
a
Ibrahim Yalcouye | Master (Mixed Mode) | 08 Apr 2024 - 09 Feb 2025
Thesis: 2D ligand-based similarity searching and structure-based virtual screening for identification of potential Porphyromonas gingivalis peptidylarginine deiminase inhibitors as rheumatoid arthritis pharmacotherapy
a
Asveene | Doctorate | 02 Apr 2024 - 30 Jun 2024
Thesis: In Silico Studies of Herbal Extraction
a
Mervin Lee Weng Onn | Master (Coursework) | 01 Mar 2024 - 31 Aug 2024
Thesis: Examining the Relationship Between Social Determinants of Health and Healthcare Utilisation Patterns Through Elderly Population Dataset
a
Cheong Yih Jeng | Master (Coursework) | 01 Mar 2024 - 31 Aug 2024
Thesis: Molecular Dynamics Simulation of Hyperphosphorylated Tau Protein with Potential Ligands from Drug Repurposing with Progesterone, Ampicillin and Benzylpenicillin.
a
NISHALINI KURUP GOPALAKRISHNAN | Master (Coursework) | 01 Mar 2023 - 30 Aug 2023
Thesis: MOLECULAR DYNAMICS SIMULATION OF HYPERPHOSPHORYLATED TAU PROTEIN WITH POTENTIAL LIGANDS FROM DRUG REPURPOSING IN ALZHEIMER’S DISEASE
a
ONG MUN LING | Master (Mixed Mode) | 11 Sep 2022 - 30 Jun 2024
Thesis: Electronic health (eHealth): Knowledge, attitudes, and practices among Malaysian community pharmacists - A survey study
a
Irene Huong Yeu Xin | Master (Mixed Mode) | 01 Sep 2022 - 28 Feb 2023
Thesis: Molecular Dynamics Simulation of Orientin on Beta Amyloid Biosynthesis Enzyme.
a
Kee Kye Vern | Master (Coursework) | 01 Mar 2022 - 31 Aug 2022
Thesis: Computational Drug Repurposing for Hyperphosphorylated Tau Protein in Alzheimer’s Disease Using Molecular Dynamics Simulation.
a
Nuraini Binti Naim | Master (Coursework) | 01 Mar 2022 - 31 Aug 2022
Thesis: Data Analytics on Trend of C-reactive Protein (CRP) Level and Its Correlation with Other Clinical Parameters in Describing Disease Progression of Mild COVID-19 Patients.
a
Leong How Wan | Master (Mixed Mode) | 01 Mar 2022
Thesis: In silico pharmacokinetic and molecular docking studies of labdane diterpenes of Alpinia genus against butyrylcholinesterase, a therapeutic target for Alzheimer’s disease.
a
Ain Syafiza Mohd Amin | Master (Coursework) | 01 Sep 2021 - 28 Feb 2022
Thesis: Comparative Molecular Dynamics Simulation on Wild Type and Mutant Type USP9X Catalytic Domain
a
Amina Ismail Hussein | Master (Mixed Mode) | 01 Sep 2021 - 28 Feb 2022
Thesis: In Silico characterisation and In vitro validation of orientin on secretase activities.
a
Ling Suk Jiun | Doctorate | 01 Jan 2018 - 01 Nov 2022
Thesis: Design of novel glycyrrhizic acid and/or glycyrrhetic acid analogues as PPAR-α/γ dual agonists.
a
Kho Mee Teck | Master (Research) | 08 Jan 2013 - 01 Dec 2016
Thesis: Characterising host-parasite metabolic interaction of Toxoplasma gondii infection in murine model: A system biology approach.