Gnanajothy Ponnudurai



Salutation
Associate Professor Dr

School/Centre
School of Medicine

Department
Human Biology

Appointment
Deputy Dean for Medical Sciences, Industrial & International Engagement

Position
Associate Professor




Education

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Doctor of Philosophy (PhD) (Biochemistry (Toxinology)), 1995 University of Malaya
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Master of Science (Biochemistry (Toxinology)), 1991 University of Malaya
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Bachelor of Science (Hons) (Biochemistry), 1988 University of Malaya

Memberships

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Malaysian Society on Toxinology Committee 2008 - 2010
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Malaysian Society on Toxinology Secretary 1997 - 2007

Research Funding
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Post-prandial hyperglycemia during Ramadan fasting using a 24-hour continuous glucose monitoring system in Malaysian individuals. IMU Internal Research Grant | 2025-01-01 - 01 Oct 2026
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Assessment of English proficiency among year 1 undergraduate medical students using readability analysis IMU Internal Research Grant | 2024-11-15 - 15 Nov 2025
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Qualitative assessment to identify types of reflective reports and development of a software-based algorithm to identify types of emotion in the reflective reports written by undergraduate medical students IMU Internal Research Grant | 2024-06-01 - 31 Dec 2025
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Relationship between hand dexterity and basic suturing technique among medical students IMU Internal Research Grant | 2024-02-01 - 31 Jul 2025
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Development of a peer assessment tool to assess individual performance of healthcare professions undergraduates in small group learning IMU | 2019-01-01 - 01 Aug 2020

Publications

Research Articles

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Melatonin induces apoptosis and inhibits the proliferation of cancer cells via reactive oxygen species-mediated MAPK and mTOR pathways CLINICAL CANCER DRUGS 2020
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A study of the nature and level of trust between patients and healthcare providers, its dimensions and determinants: a scoping review protocol BMJ OPEN 2020
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Melatonin inhibits high glucose-induced ox-LDL/LDL expression and apoptosis in human umbilical endothelial cells HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION 2020
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Melatonin promotes Schwann cell dedifferentiation and proliferation through the Ras/Raf/ERK and MAPK pathways, and glial cell‑derived neurotrophic factor expression EXPERIMENTAL AND THERAPEUTIC MEDICINE 2020
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Melatonin prevents oxidative stress-induced mitochondrial dysfunction and apoptosis in high glucose-treated schwann cells via upregulation of Bcl2, NF-κB, mTOR, Wnt signalling pathways ANTIOXIDANTS 2019
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para‐Phenylenediamine induces apoptosis through activation of reactive oxygen species‐mediated mitochondrial pathway, and inhibition of the NF‐κB, m TOR, and W nt pathways in human urothelial cells ENVIRONMENTAL TOXICOLOGY 2017
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Melatonin protects against hyperglycemia-induced Schwann cells apoptosis through MTOR and Wnt signaling pathways CONFERENCE ABSTRACT: 14 TH MEETING OF THE ASIAN-PACIFIC SOCIETY FOR NEUROCHEMISTRY. DOI: 10.3389/CONF. FNCEL 2016
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para-Phenylenediamine-induces apoptosis via a pathway dependent on PTK-Ras-Raf-JNK activation but independent of the PI3K/Akt pathway in NRK-52E cells MOLECULAR MEDICINE REPORTS 2015
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Purification and antibacterial activities of an L-amino acid oxidase from king cobra (Ophiophagus hannah) venom JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES 2012
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Cross neutralization of Hypnale hypnale (hump-nosed pit viper) venom by polyvalent and monovalent Malayan pit viper antivenoms in vitro and in a rodent model ACTA TROPICA 2011
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Enzymatic and toxinological activities of Hypnale hypnale (hump-nosed pit viper) venom and its fractionation by ion exchange high performance liquid chromatography JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES 2011
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Pre And Post PBL Meetings In Ensuring The Quality Of Facilitators In Problem Based Learning JOURNAL IEJSME 2010
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Enzymatic and immunological properties of Bungarus flaviceps (red-headed krait) venom JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES 2010
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Protein profile analysis of Malaysian snake venoms by two-dimensional gel electrophoresis JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES 2010
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The levels of difficulty and discrimination indices in type A multiple choice questions of pre-clinical semester 1 multidisciplinary summative tests IEJSME 2009
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Medical Students' Perception of a Hybrid Problem-based Curriculum **-(TM), 2009
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Serum kinetics of Calloselasma rhodostoma (Malayan pit viper) venom components in a rabbit JOURNAL OF VENOMOUS ANIMALS AND TOXINS INCLUDING TROPICAL DISEASES 2009
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Biology at Pre-university Level: Does This Provide an Advantage to Medical Students? **-(TM), 2007
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Improving PBLs in the International Medical University: defining the ‘good’PBL facilitator MEDICAL TEACHER 2006
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Perception of Facilitators in a Medical Curriculum **-(TM), 2003
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Monitoring the effectiveness of PBL amongst undergraduate medical students at Malaysian medical school **-(TM), 2002
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Proteolytic specificity of rhodostoxin, the major hemorrhagin of Calloselasma rhodostoma (Malayan pit viper) venom TOXICON 1997
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The toxinology of Calloselasma rhodostoma (Malayan pit viper) venom JOURNAL OF TOXICOLOGY: TOXIN REVIEWS 1996
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Electrophoretic profiles and biological activities: intraspecific variation in the venom of the Malayan pit viper (Calloselasma rhodostoma) TOXICON 1996
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Structural Studies of a Major Hemorrhagin (Rhodostoxin) from the Venom ofCalloselasma rhodostoma (Malayan Pit Viper) ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1996
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Structural analysis of the major haemorrhagin from Calloselasma rhodostoma (Malayan pit viper) venom. TOXICON 1995
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Cross-reactivity of malayan pit viper (Calloselasma rhodostoma) and lance-headed pit viper (Trimeresurus) antivenoms against Malaysian pit viper venoms SNAKE-NITTAGUN- 1995
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Purification and properties of the L-amino acid oxidase from Malayan pit viper (Calloselasma rhodostoma) venom ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS 1994
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An investigation on the antigenic cross-reactivity of Calloselasma rhodostoma (Malayan pit viper) venom hemorrhagin, thrombin-like enzyme and L-amino acid oxidase using enzyme-linked immunosorbent assay TOXICON 1994
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Cross-reactivity of monovalent and polyvalent Trimeresurus antivenoms with venoms from various species of Trimeresurus (lance-headed pit viper) snake TOXICON 1994
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A comparative study on the biological properties of venoms from juvenile and adult common tiger snake (Notechis scutatus) venoms COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY PART B: COMPARATIVE BIOCHEMISTRY 1993
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Isolation and characterization of a hemorrhagin from the venom of Calloselasma rhodostoma (Malayan pit viper) TOXICON 1993
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A comparative study of the biological properties of venoms from juvenile and adult inland taipan (Oxyuranus microlepidotus) snake venoms TOXICON 1993
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A comparative study on the electrophoretic patterns of snake venoms. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. B, COMPARATIVE BIOCHEMISTRY 1992
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A comparative study of the biological properties of venoms of some old world vipers (Subfamily Viperinae) INTERNATIONAL JOURNAL OF BIOCHEMISTRY 1992
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The biological properties of venoms of some American coral snakes (genus Micrurus) COMPARATIVE BIOCHEMISTRY PHYSIOLOGY 1992
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Comparative study of the enzymatic, hemorrhagic, procoagulant and anticoagulant activities of some animal venoms. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. C, COMPARATIVE PHARMACOLOGY AND TOXICOLOGY 1992
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Biochemical characterization of snake venoms RECENT ADVANCES IN TOXINOLOGY RESEARCH. SINGAPORE: VENOM & TOXIN RESEARCH GROUP 1992
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A comparative study of the biological activities of rattlesnake (genera Crotalus and Sistrurus) venoms COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY PART C: COMPARATIVE PHARMACOLOGY 1991
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A comparative study of the biological properties of some sea snake venoms. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. B, COMPARATIVE BIOCHEMISTRY 1991
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A comparative study of the biological properties of Dendroaspis (mamba) snake venoms. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. C, COMPARATIVE PHARMACOLOGY AND TOXICOLOGY 1991
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A comparative study of the biological properties of some venoms of snakes of the genus Bothrops (American lance-headed viper). COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. B, COMPARATIVE BIOCHEMISTRY 1991
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A comparative study of the biological activities of venoms from snakes of the genus Agkistrodon (moccasins and copperheads) COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY PART B: COMPARATIVE BIOCHEMISTRY 1990
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A comparative study of the biological properties of krait (genus Bungarus) venoms. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. C, COMPARATIVE PHARMACOLOGY AND TOXICOLOGY 1990
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A comparative study of the biological properties of Australian elapid venoms COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY PART C: COMPARATIVE PHARMACOLOGY 1990
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A comparative study of the biological properties of venoms from snakes of the genus Vipera (true adders) COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. B, COMPARATIVE BIOCHEMISTRY 1990

Other Publications

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Pharmacokinetics of the venom of humped-nose pit viper (Hypnale hypnale) in rabbits JOURNAL OF PHARMACOLOGICAL SCIENCES | 01 Jan 2011
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Studies on the epitopes of Malayan pit viper venom hemorrhagin FEBS JOURNAL | 01 Jan 2005