ANIL PHILIP KUNNATH



Salutation
Dr

School/Centre
School of Health Sciences

Department
Applied Biomedical Science and Biotechnology

Position
Senior Lecturer

Email
anilphilip_kunnath@imu.edu.my



Education

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PhD (Cancer Genetics), 2015 International Medical University
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MSc (Medical Laboratory Technology), 2004 University of Calicut, India
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BSc (Medical Laboratory Technology), 1999 Mahatma Gandhi University, Kerala, India

Memberships

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Institute of Biomedical Science | International | Fellow

Research Funding
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A pilot study for psychoeducation program on quality of life among primary caregivers of children with Cerebral Palsy IMU Internal Research Grant | 13 Jun 2024 - 31 Dec 2025
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Transcriptomic analysis to study the effect of palm-derived nutrients on insulin-resistant cell lines. IMU Internal Research Grant | 10 Jun 2024 - 14 Sep 2024
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Study on Awareness, Adoption Willingness, Utility of mHealth mobile application in Self-Monitoring Blood Glucose among diabetic patients in Awam Clinic Glenmarie and IMU clinic. IMU Internal Research Grant | 15 Jun 2023 - 02 Oct 2023
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Review of endoscopic duodenal biopsies in patients with gastrointestinal symptoms to study the relationship between functional dyspepsia and duodenal eosinophilia in PHKL hospital. IMU Internal Research Grant | 15 Jun 2023 - 02 Oct 2023
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Evaluation study on Knowledge and Attitude regarding Virtual Autopsy as a recent advancement of forensic investigation among medical/biomedical students of IMU. IMU Internal Research Grant | 15 Jun 2023 - 01 Oct 2023
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Comparative study on the effectiveness of Digital Pathology vs Traditional Pathology among undergraduate science students in Malaysia IMU Internal Research Grant | 15 Jun 2023 - 01 Oct 2023
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Systematic review of the marine algal bioactive compounds and its antidiabetic potential Internal Grant | 15 Jul 2022 - 21 Sep 2022
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Scoping review on marine fungal bioactive secondary metabolites as neuroprotective agents Internal Grant | 14 Jul 2022 - 14 Sep 2022
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Review of endoscopic duodenal biopsies in patients with gastrointestinal Symptoms to study the relationship between functional dyspepsia and duodenal eosinophilia Internal Grant | 15 Jul 2021 - 15 Sep 2021
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A retrospective review of the functional and aesthetic outcome of rhinoplasty in PHKL hospital Kuala Lumpur Internal Grant | 15 Jul 2021 - 15 Sep 2021
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Role of the interprofessional team for the differential diagnosis of neck abscesses- A retrospective review of neck abcess cases presented in PHKL from January 2016 to Dec 2020 Internal Grant | 15 Jul 2021 - 16 Sep 2021
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Review of endoscopic duodenal biopsies to estimate the prevalence of coeliac disease in PHKL patients with gastrointestinal symptoms Internal Grant | 14 Jul 2021 - 10 Sep 2021
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Assessing the Potential of Nano-delivery Systems Containing Zerumbone in Targeting Inflammation MSc in Molecular Medicine | 05 Apr 2021 - 28 Feb 2022
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A retrospective preliminary study to detect the ENT foreign bodies (FB) and its occurrences in PHKL Internal Grant | 24 Jul 2020 - 17 Sep 2020
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Review of endoscopic duodenal biopsies in patients with gastrointestinal symptoms-Relationship between villous atrophy and coeliac disease Internal Grant | 16 Jul 2020 - 17 Sep 2020
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Canonical Hedgehog signaling in colorectal cancer. Internal Grant | 16 Jul 2020 - 16 Sep 2020
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A retrospective preliminary study to detect the incidence and cause of epistaxis in PHKL Internal Grant | 16 Jul 2020 - 17 Sep 2020
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A review of the results of the Filmarray PCR based Gastrointestinal Pathogen (GIP) panel stool test in patients with acute gastroenteritis Internal Grant | 15 Jul 2020 - 17 Sep 2020
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Review of endoscopic duodenal biopsies in patients with gastrointestinal symptoms-Relationship between low grade duodenal inflammation and functional dyspepsia Internal Grant | 15 Jul 2020 - 16 Sep 2020
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KRAS mutations in colorectal cancer and activation of the Gli-1 transcription factor Internal Grant | 14 Jul 2020 - 16 Sep 2020
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Assessment of anti-cancer potential of different types of marine organism extracts on MDA-MB-231 and MCF-7 Human Breast Cancer Cells Internal Grant | 09 Jul 2020 - 16 Sep 2020
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Antihyperglycemic potential of the crude extracts of Caulerpa Racemosa in low dose streptozotocin induced Type 2 diabetic rats Internal Grant | 18 Jul 2019 - 13 Sep 2019
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Assessing the anti-inflammatory potential of Rhamnetin nanparticles using immortalized bronchial epithelial cells as a therapeutic intervention for asthma Internal Grant | 11 Jul 2019 - 17 Oct 2019
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Relationship between platelet indices and coronary heart disease-A case control study Internal Grant | 10 Jul 2019 - 12 Sep 2019
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Assessing the potential of the extracts of the brown seaweed, Padina australis as antihyperglycaemic agent Internal Grant | 16 Aug 2018 - 15 Nov 2018
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Induction of intracellular cell death in breast cancer cells by silencing MUC1, RAD51 and PAR1 using carbonite apatite nanoparticles Internal Grant | 12 Jul 2018 - 12 Sep 2018
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Induction of intracellular cell death of MCF-7 cell lines by silencing SKP-2, PLK-1 and CHK-1 in breast cancer cells using carbonite apatite nanoparticle Internal Grant | 12 Jul 2017 - 10 Aug 2017
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Silencing spindle association check point (SAC) proteins- CDC 20, Mad 2 and BubR1 in breast cancer cells using carbonite apatite nanoparticles Internal Grant | 12 Jul 2016 - 10 Sep 2016
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Viability of bifidobacteria and lactobacilli in simulated gastric juice and bile solutions Internal Grant | 10 Jul 2015 - 09 Sep 2015
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Intracellular proteinase delivery using pH -sensitive nanoparticles for anti -tumor activity Internal Grant | 10 Jun 2010 - 12 Aug 2010
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• Silencing of tyrosine kinase gene expression for inhibition of cancer cell proliferation and survival Internal Grant | 09 Jun 2010 - 06 Aug 2010
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Nanoparticle mediated delivery of small interfering RNAs(siRNAs) against cell adhesion receptor genes for tumor cell killing in presence or absence of anticancer drugs Internal Grant | 14 Apr 2010 - 15 Jul 2010

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Publications

Research Articles

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Bacterial Persister Cells and Development of Antibiotic Resistance in Chronic Infections: An Update BRITISH JOURNAL OF BIOMEDICAL SCIENCE | 2024
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Hypoglycaemic Molecules for the Management of Diabetes Mellitus from Marine Sources DIABETES, METABOLIC SYNDROME AND OBESITY | 2023
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Duodenal eosinophilia is associated with symptomatic erosive gastro-oesophageal reflux disease, presence of co-morbidities, and ethnicity but not undifferentiated functional dyspepsia: A retrospective Malaysian study THE MEDICAL JOURNAL OF MALAYSIA | 2022
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Evaluation of the association between duodenal eosinophil counts, functional dyspepsia, symptomatic erosive GERD and other variables: A retrospective multi-ethnic Malaysian study. N/A | 2021
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A retrospective audit of endoscopic duodenal biopsies to uncover undetected Coeliac disease in Malaysian patients. THE MEDICAL JOURNAL OF MALAYSIA | 2021
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Nutritional profile, antioxidative and antihyperglycemic properties of Padina tetrastromatica from Tioman Island, Malaysia FOODS | 2021
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Applications of nanocarriers as drug delivery vehicles for active phytoconstituents Current pharmaceutical design | 2020
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Bioprospecting Cultivated Tropical Green Algae, Caulerpa racemosa (Forsskal) J. Agardh: A Perspective on Nutritional Properties, Antioxidative Capacity and Anti-Diabetic Potential. FOODS (BASEL, SWITZERLAND) | 2020
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Biological and therapeutic potential of the edible brown marine seaweed Padina australis and their pharmacological mechanisms JOURNAL OF TROPICAL BIOLOGY & CONSERVATION (JTBC) | 2020
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Bioprospecting cultivated tropical green algae, Caulerpa racemosa (Forsskal) J. Agardh: a perspective on nutritional properties, antioxidative capacity and anti-diabetic potential Foods | 2020
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Biological and therapeutic potential of the edible brown marine seaweed Padina australis and their pharmacological mechanisms N/A | 2020
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Relationship between Platelet Indices and Coronary Heart Disease in Malaysian Population JOURNAL OF BIOMEDICAL SCIENCES | 2020
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Potential Applications of Circulating Tumor DNA Technology as a Cancer Diagnostic Tool CUREUS | 2019
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Current status on immunological therapies for type 1 diabetes mellitus Current diabetes reports | 2019
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Therapeutic Potential of Tumor Suppressors in Treating Breast Cancer INT J CANCER STUD RES | 2018
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Cord Blood Transplantation and Treatment of Cancer INTERNATIONAL JOURNAL OF BIOINFORMATICS AND BIOLOGICAL SCIENCE | 2018
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INDUCTION OF INTRACELLULAR DEATH OF BREAST CANCER CELLS THROUGH COMBINED INTRACELLULAR DELIVERY OF A TUMOR-SUPPRESSOR GENE AND SMALL INTERFERING RNAS AGAINST GROWTH FACTOR RECEPTOR AND ANTI-APOPTOTIC GENES N/A | 2015
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Nanoparticle-facilitated intratumoral delivery of Bcl-2/IGF-1R siRNAs and p53 Gene synergistically inhibits tumor growth in immunocompetent mice J NANOMED NANOTECHNOL S | 2014
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Intracellular delivery of ERBB2 siRNA and p53 gene synergistically inhibits the growth of established tumour in an immunocompetent mouse J CANCER SCI THER | 2014
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P0059 Induction of apoptosis in breast cancer cells through combined intracellular delivery of a tumour-suppressor gene and small interfering RNAs against growth factor receptor and anti-apoptotic genes European Journal of Cancer | 2014
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Intracellular delivery of NF-κB small interfering RNA for modulating therapeutic activities of classical anti-cancer drugs in human cervical cancer cells DRUGS AND THERAPY STUDIES | 2013
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Reversing multidrug resistance in breast cancer cells by silencing ABC transporter genes with nanoparticle-facilitated delivery of target siRNAs International journal of nanomedicine | 2012
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Fabrication and intracellular delivery of siRNA/carbonate apatite nano-composites for effective knockdown of cyclin B1 gene DRUGS AND THERAPY STUDIES | 2011
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Frecuencia de la radiación electromagnética de radio (RF-EMR) de GSM (0.9/1.8 GHz) teléfonos móviles induce el estrés oxidativo y reduce la motilidad de los espermatozoides en ratas CLíNICAS (SAO PAULO) | 2009
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Radio frequency electromagnetic radiation (RF-EMR) from GSM (0.9/1.8 GHz) mobile phones induces oxidative stress and reduces sperm motility in rats Clinics | 2009
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I Jayalekshmi H, Koduru B, Valsalan R. Radio frequency electromagnetic radiation (RF-EMR) from gsm (0.9/1.8 ghz) mobile phones induces oxidative stress and reduces sperm motility in rats Clinics | 2009
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Ethanol intoxication--dose dependent effect on circulating testosterone level in Wistar rats. Indian journal of physiology and pharmacology | 2008
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FLT3 GENE INTERNAL TANDEM DUPLICATION IN ADULT ACUTE MYELOID LEUKEMIA PATIENTS. Malaysian Journal of Medical Sciences | 2007

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Other Publications

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Exercise Immunology: The promises and challenges of Ayurveda in the current health care system International online conference on Holistic Approach to Immunity to Microbial Diseases and their Treatment (HMDT 2020) | 12 Sep 2020
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Targeted Delivery of Protease-Activated Receptor 1(PAR 1)-siRNA by carbonite apatite nanoparticles suppresses breast cancer growth International Conferenece on Medical and Health Sciences | 24 Apr 2019
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A comparative study of inhibition of breast cancer cells in both in vitro and in vivo approaches by combined intracellular delivery of HER2 and BCL2 siRNAs with p53 plasmid using carbonite apatite nanoparticle versus anticancer drugs 8th Annual Asian Oncology Summit | 03 Mar 2016
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Assessment of Theerapeutic Efficacy of Carbonate apatite Nanoparticle meidtaed gene delivery for the treatment of breast cancer 3rd International conference on Biotechnology Engineering | 02 Jul 2013
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siRNA gene silecing effect in breast cancer cell lines Pharma Tech | 20 Nov 2012
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EGFR, IGFR gene silencing effect on Breast cancer cell lines 4th Malaysian Tissue Engineering & Regenerative Medicine Scientific Meeting | 03 Jun 2012
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Formulation of siRNA/carbonate apatite nanocomposites for effieicnet silencing of cancer related genes 3rd International confernece on Nanotechnology | 28 Nov 2011
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Nanoparticle meadiated targeted delivery of gene silencing elements for the treatment of cancer Second World Congress on Cancer | 03 Sep 2010

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Supervisions
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Fathimath Zana Zahir | Undergraduate | 15 Jun 2023 - 20 Sep 2023 Thesis: Comparative study on the effectiveness of Digital Pathology vs Traditional Pathology among undergraduate science students in IMU
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Ahmad Al-Amin Bin Mohamed | Undergraduate | 15 Jun 2023 - 02 Oct 2023 Thesis: Study on Awareness, Adoption Willingness, Utility of mHealth mobile application in Self-Monitoring Blood Glucose among diabetic patients in Awam Clinic Glenmarie and IMU clinic.
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Farisha Shahira Binti Muhammad Arshad | Undergraduate | 15 Jun 2023 - 01 Oct 2023 Thesis: Evaluation study on Knowledge and Attitude regarding Virtual Autopsy as a recent advancement of forensic investigation among medical/biomedical students of IMU.
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Liau Kang Hui | Undergraduate | 04 Apr 2023 - 21 Sep 2023 Thesis: Review of endoscopic duodenal biopsies in patients with gastrointestinal Symptoms to study the relationship between functional dyspepsia and duodenal eosinophilia