Anna Krasilnikova
Salutation
Associate Professor Dr
School/Centre
School of Medicine
Department
Pharmacology and Therapeutics
Position
Associate Professor
Education
a
PhD (Pharmacology and Clinical Pharmacology), 2004
Volgograd State Medical University
a
MD (Clinical Pharmacology), 2002
Volgograd State Medical University
a
Clinical internship (Internal Medicine), 1999
Volgograd State Medical University
a
MBBS (General Medicine), 1998
Volgograd State Medical University
Memberships
a
Malaysian Society of Pharmacology and Physiology (MSPP)
Member
2013 - Present
Research Funding
a
Characterization of antimicrobial peptides from the larvae of black soldier fly, Hermetia illucens (L.) (Diptera: Stratiomyidae) and blowfly, Chrysomya megacephala (F.) (Diptera: Calliphoridae)
FRC | 01 Jan 2021 - 31 Dec 2023
a
Mechanism of antiviral action of novel N-substituted 5-(phenylamino)uracil derivatives Z214 and Z364 targeting annexin A2.
RMC/GPK | 01 Dec 2020 - 30 Nov 2022
a
Investigating the role of N-substituted 5-(phenylamino)uracil derivatives in annexin A2 as a possible mechanism of antiviral action against chikungunya virus: In vitro study.
UITMSEL | 01 Dec 2020 - 30 Nov 2022
a
Antioxidant Activity Of Novel N-substituted 5 (Phenylamino) Uracil Derivatives In Chikungunya Virus Infected Vero Cells.
UiTMSEL | 01 Jul 2020 - 30 Jun 2022
a
Dose and time depended effects of inhibitors of renin angiotensin system on dexamethasone induced extracellular matrix deposition on cultured human trabecular meshwork cells
BESTARI: | 01 Jan 2017 - 31 Dec 2018
a
Effects of resveratrol on ECM deposition by steroid-pretreated trabecular meshwork cells.
LESTARI | 01 Aug 2016 - 31 Jul 2018
a
Study to elucidate stimulation of matrix metalloproteinase secretion as mechanism of resveratrol-induced intraocular pressure reduction.
LESTARI | 01 Aug 2016 - 31 Jul 2018
a
Involvement of C-JUN phosphorylation in the protective effect of magnesium acetyltaurinate against endothelin-1-induced RGC apoptosis.
LESTARI | 01 Aug 2016 - 31 Jul 2018
a
Antiviral activity of 1-substituted 5-(phenylamino)uracil derivatives against chikungunya virus.
LESTARI | 01 Aug 2016 - 31 Jul 2018
a
Effect of magnesium acetiltaurate on minerals and trace elements concentration in the rat retina after NMDA exposure.
LESTARI | 01 Aug 2016 - 31 Jul 2018
a
Studies to elucidate suppression of TGF-ß2 as the mechanism of resveratrol-induced oculohypotension: In vivo and in vitro studies. Top-Down FRGS: 600-RMI/FRGS TD 5/3 (2/2015)
FRGS | 01 Aug 2015 - 31 Jul 2018
a
Antiviral activity of porcupine bezoar against dengue virus. 600-IRMI/DANA 5/3/BESTARI (00015/2016)
BESTARI | 01 Jan 2015 - 31 Dec 2016
a
Elucidation of adenosine receptor signalling mechanism involved in resveratrol-induced ocular hypotension: In vivo and in vitro studies.
FRGS | 01 Aug 2014 - 31 Jul 2017
a
Discovery and optimization of imidazolbenzimidazoles as Rho-kinase (Rock) inhibitors for IOP lowering effect in normotensive and oculohypertensive rats.
RAGS | 01 Aug 2014 - 31 Jul 2016
a
BDNF-related anti-neurogenerative mechanism and histopathological basis of behavioural changes in amyloid-induced neurodegenerative diseases.
FRGS | 01 Aug 2014 - 31 Jul 2017
a
Anti-remodeling mechanism of renin-angiotensin system inhibitors on trabecular meshwork: Role of TGFβ.
FRGS | 01 Jan 2014 - 01 Jan 2017
a
Novel 5-Phenylaminouracil Derivates: Mechanism of action and Anti-Dengue Virus Effect.
RAGS | 01 Aug 2013 - 31 Jul 2015
a
Studies to Investigate Trabecular Tissue Remodeling as a Mechanism of IOP Lowering Effect of Angiotensin II Type 1 Receptor Blockers in Ocularhypertensive Rats.
RAGS | 01 Aug 2012 - 31 Jul 2014
a
Effects of Angiotensin Converting Enzyme Inhibitors on Trabecular Meshwork Remodelling in Oculohypertensive Rats.
Dana Kecemerlangan | 01 Jan 2012 - 01 Jan 2014
a
Mechanism of Ocular Hypotensive Action of Angiotensin Converting Enzyme Inhibitors
Dana Kecemerlangan Penyelidikan | 01 Jan 2011 - 01 May 2012
Publications
Research Articles
a
Antimicrobial Activity of Black Soldier Fly, Hermetia illucens (Diptera: Stratiomyidae) Larval Hemolymph against Various Pathogenic Bacteria.
JOURNAL OF PURE & APPLIED MICROBIOLOGY 2023
a
Antimicrobial peptides isolated from insects and their potential applications
JOURNAL OF ASIA-PACIFIC ENTOMOLOGY 2022
a
Brief overview of the currently available COVID-19 vaccines
JOURNAL OF CLINICAL AND HEALTH SCIENCES 2022
a
Effect of dexamethasone on the expression of MMPs, adenosine A1 receptors and NFKB by human trabecular meshwork cells
JOURNAL OF BASIC AND CLINICAL PHYSIOLOGY AND PHARMACOLOGY 2020
a
Effect of trans-resveratrol on dexamethasone-induced changes in the expression of MMPs by human trabecular meshwork cells: Involvement of adenosine A1 receptors and NFkB
EUROPEAN JOURNAL OF PHARMACOLOGY 2020
a
Determination of potential solvents for novel N-substituted 5-(phenylamino) uracil derivatives and evaluation of their cytotoxic effects on Vero 76 Cells
ASIA-PACIFIC JOURNAL OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY 2019
a
Topical losartan reduces IOP by altering TM morphology in rats with steroid-induced ocular hypertension
INDIAN J PHYSIOL PHARMACOL 2018
a
Neuroprotective effect of magnesium acetyltaurate against NMDA-induced excitotoxicity in rat retina
NEUROTOXICITY RESEARCH 2017
a
The effect of trans-resveratrol on the viability of human trabecular meshwork cells
RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES 2017
a
Protective effect of magnesium acetyltaurate against NMDA-induced retinal damage involves restoration of minerals and trace elements homeostasis
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY 2017
a
Magnesium acetyltaurate prevents retinal ganglion cells apoptosis induced by N-methyl-D-aspartate
FRONT. CELL. NEUROSCI. CONFERENCE ABSTRACT: 14TH MEETING OF THE ASIAN-PACIFIC SOCIETY FOR NEUROCHEMISTRY 2016
a
Protective effect of magnesium acetyltaurate against endothelin-induced retinal and optic nerve injury
NEUROSCIENCE 2016
a
Mechanism of the anticataract effect of liposomal magnesium taurate in galactose-fed rats
MOLECULAR VISION 2016
a
Time-and dose-dependent effects of Amyloid Beta 1-40 (Aß1-40) peptide on retinal ganglion cell survival: TUNEL assay
FRONT. CELL. NEUROSCI. CONFERENCE ABSTRACT: 14TH MEETING OF THE ASIAN-PACIFIC SOCIETY FOR NEUROCHEMISTRY 2016
a
Magnesium acetyltaurate inhibits nitric oxide synthase expression induced by N-methyl-D-aspartate
FRONT. CELL. NEUROSCI. CONFERENCE ABSTRACT: 14TH MEETING OF THE ASIAN-PACIFIC SOCIETY FOR NEUROCHEMISTRY 2016
a
The effect of dexamethasone on synthesis of collagen, fibronectin and α-smooth muscle actin in cultured human trabecular meshwork cells
IND J PHYSIOL PHARMACOL 2016
a
Mechanisms of angiotensin converting enzyme inhibitor-induced IOP reduction in normotensive rats
EUROPEAN JOURNAL OF PHARMACOLOGY 2014
a
Comparison of 24-hour ocular hypotensive effect of single drop application of enalaprilat and losartan in steroid-induced ocular hypertensive rat model.
ACTA PHARMACOLOGICA SINICA 2013
a
Прикладная фармакоэкономика
OE.: ",-OE 2005
a
Фармакоэкономические аспекты применения азитромицина различных производителей при внебольничной пневмонии у взрослых
, 2003
Other Publications
a
Potential agents against chikungunya virus
5th International Scientific and Practical Conference “Modern Challenges in the Treatment of Infectious Diseases | 22 Mar 2023
a
Current State of Covid-19 Vaccine Development
4th International Scientific and Practical Conference “Modern Challenges in the Treatment of Infectious Diseases” | 23 Mar 2022
a
Current State of Covid-19 Vaccine Development
4th International Scientific and Practical Conference “Modern Challenges in the Treatment of Infectious Diseases” | 23 Mar 2022
a
Current State of Covid-19 Vaccine Development
4th International Scientific and Practical Conference “Modern Challenges in the Treatment of Infectious Diseases” | 23 Mar 2022
a
Role of renin-angiotensin system inhibitors in attenuation of dexamethasone-induced ECM remodeling in human trabecular meshwork cells
Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 (The 18th World Congress of Basic and Clinical Pharmacology) | 01 Jan 2018
a
Sodium Benzoate as a Solvent for the Novel Hydrophobic 5-Phenylaminouracil Derivatives: Evaluation of Cytotoxic Effect in Vero 76 Cell Culture
PUBLIC HEALTH GENOMICS | 01 Jan 2015
a
Comparison of 24-h ocular hypotensive effect of single drop application of enalaprilat and losartan in steroid-induced ocular hypertensive rat model
ACTA PHARMACOLOGICA SINICA | 01 Jan 2013
a
Oculohypotensive effect of topical losartan potassium in ocular normotensive and steroid-induced ocular hypertensive rat models
ACTA PHARMACOLOGICA SINICA | 01 Jan 2013
a
IOP lowering effect of losartan and latanoprost in oculohypertensive rats: A comparative evaluation
ACTA PHARMACOLOGICA SINICA | 01 Jan 2013
a
Role of MMP, TNF-alpha and angiotensin II receptors in the ocular hypotensive action of angiotensin converting enzyme inhibitors.
IVth Russian Congress of Pharmacology (Innovations in Modern Pharmacology), Korston Hotel & Mall, Kazan, Russian Federation, September, 18-21 2012 | 01 Jan 2012
a
Potential mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitors.
46th Malaysia-Singapore Congress of Medicine 12-14 July 2012, Kuala Lumpur, Malaysia | 01 Jan 2012
Supervisions
a
Norul Azmiera Binti Zamri | Doctorate | 01 Oct 2020
Thesis: The characterization of antimicrobial peptides from the larvae of black soldier fly, Hermetia illucens (L.) (Diptera: Stratiomyidae) and blowfly, Chrysomya megacephala (F.) (Diptera: Calliphoridae)
a
Normie Aida bt Mohd Nasir | Master (Research) | 01 Mar 2015 - 15 Apr 2020
Thesis: Protective effect of trans-resveratrol on dexanethasone-induced changes in matrix metalloproteinases expression by human trabecular meshwork cells: Potential mechanisms
a
Nurul Ainsya Bakry | Master (Research) | 01 Sep 2014 - 15 Feb 2018
Thesis: Time and dose dependent effects of renin angiotensin system inhibitors on extracellular matrix deposition and modulating enzymes in dexamethasone treated human trabecular meshwork cells.
a
Noor Farah Binti Omar Ahmad | Master (Research) | 01 Mar 2014 - 01 Nov 2017
Thesis: Antiviral activity of N-substituted 5-(phenylamino)uracil derivatives against chikungunya virus
a
Mohd Aizuddin Bin Mohd Lazaldin | Doctorate | 01 Jan 2014 - 01 Jan 2020
Thesis: BDNF-related anti-neurodegenerative mechanism and histophatological basis of behavioural changes in amyloid-induced neuro-degenerative disease
a
Noor Fahitah Abu Hanipah | Doctorate | 01 Sep 2013 - 15 Dec 2019
Thesis: Novel N-substituted 5-(phenylamino)uracil derivatives: Antiviral effect against dengue and chikungunya viruses and possible mechanism of antiviral action
a
Tajul Atiqah Bt Zaulkafali | Undergraduate | 01 Sep 2012 - 31 Aug 2013
Thesis: Role of angiotensin converting enzyme inhibitors in trabecular meshwork remodeling in ocular hypertensive rats
a
Raja Nor Intan Safinaz Raja Mohd Yassin | Undergraduate | 01 Sep 2012 - 31 Aug 2013
Thesis: Mechanism of ocular hypotensive action of angiotensin converting enzyme inhibitors in rats.
a
Siti Nur Laili Mohamed | Undergraduate | 01 Sep 2012 - 31 Aug 2013
Thesis: Ocular hypotensive effects of angiotensin II type 1 receptor blockers in rat model of steroid induced ocular hypertension.