Khadijeh Gholami



Salutation
Dr

School/Centre
School of Alternative and Complementary Medicine

Department
Chiropractic Medicine

Position
Senior Lecturer


Professional Network


Education

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PhD (Molecular physiology), 2013 Universiti Malaya
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Master of Sciences (physiology), 2006 Shahid Chamran University of Ahvaz, Iran
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Bachelor of sciences (Biology (Animal Science),), 2000 University of Isfahan

Research Funding
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Estrogen alters striatin and aldosterone signaling pathways in PBMCs from diabetes men and women with or without obesity in SeDia cohort. IMU Internal Research Grant | 01 Nov 2024 - 31 Mar 2026
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Association of plasma exosomal caveolin-1 with diabetes and its complication in Seremban diabetes (SeDia) population: a potential biomarker IMU Internal Research Grant | 09 Aug 2024 - 30 Sep 2026
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Exploring the potential vascular effects of Aaptamine on the Aorta of Isopropanol-Induced Myocardial Ischemic Rats IMU Internal Research Grant | 14 Mar 2024 - 28 Feb 2025
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Striatin Deficiency: A Genetic Biomarker for Sex Dependent increased aldosterone and Salt Sensitivity of Hypertension American Heart Association Career development award | 01 Jul 2023 - 01 Jul 2026
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Preliminary studies on STRN role in vascular diseases Brigham microgrant | 14 Feb 2022 - 14 Feb 2023
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Effect of Vegetarian Diet on HbA1C and lipid profile level in normal healthy adult BPharm | 01 Jun 2018 - 31 May 2019
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Investigating the Expression and Functional Activity of CFTR and NBC and NHE in Rat Uterus Under the Influence of Sex Steroid and in different Stages of Estrous Cycle POSTGRADUATE RESEARCH FUND (PPP) | 21 Feb 2011 - 02 Feb 2012
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Differential genes expression of the proteins that are involved in uterine fluid pH regulation in rat and mouse using real time PCR POSTGRADUATE RESEARCH FUND (PPP) | 15 Apr 2010 - 15 Apr 2011

Publications

Research Articles

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Food-deprivation modulates the alfa-MSH, CCK and GIP receptors gene expression and signalling in the subfornical organ of male Wistar rats N/A | 2023
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Abstract P140: Impact Of Ovariectomy On Aldosterone And Blood Pressure In Lysine-Specific Demethylase 1 (LSD1) Deficient Mice HYPERTENSION | 2023
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Effects of a high-salt diet on MAP and expression levels of renal ENaCs and aquaporins in SHR EXPERIMENTAL BIOLOGY AND MEDICINE | 2023
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Effects of Mineralocorticoid Receptor Blockade and Statins on Kidney Injury Marker 1 (KIM-1) in Female Rats Receiving L-NAME and Angiotensin II INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2023
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The role of micronutrients in renal physiology and pathophysiology FRONTIERS IN PHYSIOLOGY | 2023
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Fasting increases circulating angiotensin levels and brain Agtr1a expression in male rats JOURNAL OF NEUROENDOCRINOLOGY | 2023
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Striatin Gene Variants Are Associated With Salt Sensitivity of Blood Pressure by Mechanisms That Differ in Women and Men HYPERTENSION | 2023
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MIND-BODY THERAPIES AND ITS EFFECT ON THE IMMUNE SYSTEM IN CHRONIC DISEASES: A LITERATURE REVIEW: Received 2020-10-16; Accepted 2021-06-02; Published 2021-11-12 JOURNAL OF HEALTH AND TRANSLATIONAL MEDICINE | 2022
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Mind-body therapies and its effects on the immune system in chronic diseases: a literature review JOURNAL OF THE UNIVERSITY OF MALAYA MEDICAL CENTRE | 2022
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Effect Of Tie2-cre Endothelial Caveolin-1 Deficiency Mice On Murine Cardiovascular And Metabolic Phenotypes HYPERTENSION | 2022
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Salt sensitivity of blood pressure and aldosterone: interaction between the lysine-specific demethylase 1 gene, sex, and age THE JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM | 2022
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Biological sex modifies aldosterone’s secretion at a cellular level JOURNAL OF ENDOCRINOLOGY | 2022
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Enhanced thrombotic responses are associated with striatin deficiency and aldosterone J AM HEART ASSOC | 2021
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A preliminary study of the effect of a high-salt diet on transcriptome dynamics in rat hypothalamic forebrain and brainstem cardiovascular control centers PEERJ | 2020
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mTORC1 deficiency modifies volume homeostatic responses to dietary sodium in a sex-specific manner ENDOCRINOLOGY | 2020
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An overview of the anatomy and physiology of the lung NANOTECHNOLOGY-BASED TARGETED DRUG DELIVERY SYSTEMS FOR LUNG CANCER | 2019
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Effect of high-salt diet on mean arterial pressure, renal epithelial sodium channels and aquaporin subunits expression levels in Spontaneously Hypertensive Rats BIORXIV | 2019
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An Analysis of the Student's Performance and Marking Process in Open-Ended Short Answer Questions in a Medical Programme: A Pilot Study. EDUCATION IN MEDICINE JOURNAL | 2019
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Differential effects of dietary flavonoids on adipogenesis EUROPEAN JOURNAL OF NUTRITION | 2019
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Effects of testosterone on mean arterial pressure and aquaporin (AQP)-1, 2, 3, 4, 6 and 7 expressions in the kidney of orchidectomized, adult male Sprague-Dawley rats ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 2017
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NMDA receptor antagonism with novel indolyl, 2-(1, 1-Dimethyl-1, 3-dihydro-benzo [e] indol-2-ylidene)-malonaldehyde, reduces seizures duration in a rat model of epilepsy SCIENTIFIC REPORTS | 2017
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Selection of suitable endogenous reference genes for qPCR in kidney and hypothalamus of rats under testosterone influence PLOS ONE | 2017
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Changes in knee laxity and relaxin receptor isoforms expression (RXFP1/RXFP2) in the knee throughout estrous cycle phases in rodents PLOS ONE | 2016
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Purslane (Portulaca oleracea) seed consumption and aerobic training improves biomarkers associated with atherosclerosis in women with type 2 diabetes (T2D) SCIENTIFIC REPORTS | 2016
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Effect of acute and chronic administration of methimazole on morphine withdrawal signs in adult male mice ZAHEDAN JOURNAL OF RESEARCH IN MEDICAL SCIENCES | 2015
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Modulation of sodium–bicarbonate co-transporter (SLC4A4/NBCe1) protein and mRNA expression in rat’s uteri by sex-steroids and at different phases of the oestrous cycle RESEARCH IN VETERINARY SCIENCE | 2014
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Differential expression of Na+/H+-exchanger (NHE-1, 2, and 4) proteins and mRNA in rodent’s uterus under sex steroid effect and at different phases of the oestrous cycle BIOMED RESEARCH INTERNATIONAL | 2013
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Investigating the expression and functional activities of the proteins that are involved in uterine fluid pH regulation at different stages of the oestrous cycle and in steroid replaced ovariectomized rats PQDT-Global | 2013
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In-vivo functional study on the involvement of CFTR, SLC26A6, NHE-1 and CA isoenzymes II and XII in uterine fluid pH, volume and electrolyte regulation in rats under different sex-steroid influence INTERNATIONAL JOURNAL OF MEDICAL SCIENCES | 2013
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Progesterone downregulates oestrogen-induced expression of CFTR and SLC26A6 proteins and mRNA in rats’ uteri BIOMED RESEARCH INTERNATIONAL | 2012

Other Publications

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Striatin Gene Variants are Associated with Reduced Striatin Levels, Salt Sensitivity of Blood Pressure, and Greater Aldosterone Levels in Women than in Men . International aldosterone conference | 13 Jun 2023
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Biological sex modifies aldosterone ' s secretion at a cellular level Connors - BRI symposium | 21 May 2023
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Effect Of Tie2 - cre e ndothelial Caveolin - 1 deficiency mice on murine cardiovascular and metabolic phenotypes . American heart association-council of hypertension | 22 Sep 2022
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Mineralocorticoid Receptor Antagonist And Lipophilic Statin Reduce Urinary Kidney Injury Marker 1 (Kim-1) In Female Rats Receiving L-NAME And Angiotensin II HYPERTENSION | 01 Jan 2020
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An analysis of students ' performance in concept - intense open - ended short answer questions in a medical programme : a pilot study Asian Medical Education Association (AMEA) Symposium, 4th Industrial Revolution: Creating A New World for Health Professions Education | 12 Apr 2019
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Castration reduces mean arterial pressure in male spontaneous hypertensive rat (SHR University of Malaya research week | 23 May 2015
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Studies on the expression and functional activities of proteins involved in uterine fluid pH regulation in female rats Society for reproduction conference | 09 Jul 2012
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Investigating the carbonic anhydrase effect on rat uterine fluid pH . The 16th Biological Science Graduate Congress | 13 Dec 2011
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Investigating the mechanisms underlying the effect of sex steroid on the uterine fluid volume and pH Malaysian society of physiology and pharmacology | 11 May 2011


Supervisions
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Alvin Wong Cheng Kang | Undergraduate | 27 Jul 2017 - 27 Jul 2018 Thesis: Effect of vegetarian diet on HbA1c level and body weight status in normal healthy adult
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TAN YONG HWA | Undergraduate | 27 Jul 2017 - 05 Feb 2019 Thesis: Body Mass Index, Nutritional knowledge and HbA1c level in Malaysia healthy adults
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TEO ROCK YEE | Undergraduate | 19 Jul 2017 - 19 Nov 2018 Thesis: blood pressure, lipid profile and nutritional knowledge in vegetarians
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TEH WEI JUN | Undergraduate | 19 Jul 2017 - 03 Feb 2019 Thesis: determination of blood pressure, lipid profile and nutritional knowledge in chinese malaysian non-vegetarian adults