Yeannie Yap Hui Yeng
Salutation
Dr
School/Centre
School of Health Sciences
Department
Applied Biomedical Science and Biotechnology
Position
Senior Lecturer
Email
Education
a
Doctor of Philosophy (Molecular Medicine), 2015
University of Malaya
a
Master of Science (Research), 2011
Universiti Tunku Abdul Rahman
a
Bachelor of Science (Honours) (Biomedical Science), 2009
Universiti Tunku Abdul Rahman
Memberships
a
Organization for Women in Science for the Developing World
Member
2019 - Present
a
International Society for Infectious Diseases (ISID)
Member
2018 - Present
a
Malaysian Society of Biochemistry and Molecular Biology
Committee
2018 - 2026
a
International Society for Mushroom Science (ISMS)
Member
2016 - Present
a
Australia Global Alumni
Member
2014 - Present
Research Funding
a
Exploring the Fundamental Biology, Biochemistry, and Genetics of the Malaysian Medicinal Mushroom Lignosus cameronensis using Omics Technologies
Fundamental Research Grant Scheme | 01 Aug 2024 - 31 Jul 2027
a
Validation of Anticancer Properties of Novel Serine Protease-Derived Peptides from Lignosus rhinocerus Using In-Silico and In-Vitro Approaches
IMU Internal Research Grant | 01 Jun 2024 - 31 May 2026
a
Clinical Investigation into the Dermal Application of L. rhinocerus TM02 water extract for mouth ulceration
MAHSA Research Grant | 13 May 2022 - 08 Nov 2023
a
Genome Mining of a Malaysian Medicinal Mushroom Lignosus tigris to Uncover Genes Encoding High-Value Bioactive (Antiproliferative) Proteins
Fundamental Research Grant Scheme | 01 Nov 2020 - 30 Apr 2024
a
Malaysia's Prized Medicinal Mushroom for Respiratory Health (Sub-Programme: Molecular Modelling of Peptide Inhibitors from Lignosus rhinocerus TM02® Targeting Cell Surface Receptors)
UM FOM Research Programme Grant 2020 (UMFRG) | 07 Aug 2020 - 14 Mar 2023
a
The Mechanistics Of Wound Healing Property and Anti-Microbial Effects of Lignosus rhinocerus
Fundamental Research Grant Scheme | 01 Sep 2019 - 30 Nov 2023
a
Investigation of the immunoregulation and therapeutic effects in oral cancer by Lignosus rhinocerotis, a traditional chinese medicine approach
MAHSA Research Grant | 02 Nov 2017 - 02 Mar 2020
a
BIOPHARMACOLOGICAL AND GENOMIC STUDIES OF MALAYSIAN MEDICINAL MUSHROOMS
Postgraduate Research Fund | 25 May 2012 - 31 Aug 2015
Publications
Research Articles
a
Comparative Cytotoxicity Evaluation of Heat-Assisted vs Cold Water Extractions of Six Medicinal Fungi against Breast and Lung Cancer Cells
FOOD TECHNOLOGY AND BIOTECHNOLOGY 2024
a
Corrigendum to The genome of Lignosus tigris: Uncovering its hidden nutraceutical potential, South African Journal of Botany, Volume 154, March 2023, Pages 108–119
SOUTH AFRICAN JOURNAL OF BOTANY 2024
a
RNA-seq transcriptome and pathway analysis of the medicinal mushroom Lignosus tigris (Polyporaceae) offer insights into its bioactive compounds with anticancer and antioxidant potential
JOURNAL OF ETHNOPHARMACOLOGY 2024
a
Usporedba citotoksičnog učinka ekstrakata šest ljekovitih gljiva dobivenih ekstrakcijom toplom vodom s onima dobivenim ekstrakcijom hladnom vodom na stanice raka dojke i pluća
FOOD TECHNOLOGY AND BIOTECHNOLOGY 2024
a
Water-soluble compounds from Lignosus rhinocerus TM02®(xLr™) modulate ACE2 activity and inhibit its interaction with SARS-CoV-2 Spike-Protein
FOOD BIOSCIENCE 2024
a
Comparative analysis of medicinal attributes between Lignosus cameronensis and its sister species
NATURAL PRODUCT RESEARCH 2024
a
The wound healing potential of Lignosus rhinocerus and other ethno-myco wound healing agents
MYCOBIOLOGY 2023
a
Assessment of self-perceived malocclusion and barriers to orthodontic treatment: A cross-sectional study
JOURNAL OF ORTHODONTIC SCIENCE 2023
a
An assessment of oral cancer knowledge, attitudes, and practices among undergraduate students in Malaysian dental schools
BMC ORAL HEALTH 2023
a
The genome of Lignosus tigris: Uncovering its hidden nutraceutical potential
SOUTH AFRICAN JOURNAL OF BOTANY 2023
a
In vivo anti-tumor activity of Lignosus rhinocerus TM02® using a MCF7-xenograft NCr nude mice model
JOURNAL OF ETHNOPHARMACOLOGY 2023
a
Activation function 1 of progesterone receptor is required for mammary development and regulation of RANKL during pregnancy
SCIENTIFIC REPORTS 2022
a
Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus
BMC BIOLOGY 2022
a
In silico analysis and characterization of medicinal mushroom cystathionine beta-synthase as an angiotensin converting enzyme (ACE) inhibitory protein
COMPUTATIONAL BIOLOGY AND CHEMISTRY 2022
a
About this Journal
HONG KONG MED J 2022
a
Immunomodulatory Effect and an Intervention of TNF Signalling Leading to Apoptotic and Cell Cycle Arrest on ORL-204 Oral Cancer Cells by Tiger Milk Mushroom, Lignosus rhinocerus
FOOD TECHNOLOGY AND BIOTECHNOLOGY 2022
a
The Prevalence and Associated Risk Factors of Carpal Tunnel Syndrome among Private Dentists in Klang Valley, Malaysia: A Cross-sectional Study
ANNALS OF DENTISTRY UNIVERSITY OF MALAYA 2022
a
In Vitro inhibition of melanin formation and enhancement of collagen production by a mushroom sclerotial water extract from the tiger milk mushroom, Lignosus rhinocerus (agaricomycetes), with No skin and eye irritation
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS 2022
a
Bioactive properties of Malaysian medicinal mushrooms Lignosus spp
FUNGAL BIOTECHNOLOGY: PROSPECTS AND AVENUES. BOCA RATON (FL) 2022
a
Volatile molecules secreted by the wheat pathogen Parastagonospora nodorum are involved in development and phytotoxicity
FRONTIERS IN MICROBIOLOGY 2020
a
The immunomodulating properties of tiger milk medicinal mushroom, Lignosus rhinocerus TM02® cultivar (Agaricomycetes) and its associated carbohydrate composition
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS 2020
a
Immunomodulatory properties of water-soluble polysaccharides extracted from the fruiting body of Chinese caterpillar mushroom, Ophiocordyceps sinensis cultivar OCS02®(Ascomycetes)
INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS 2020
a
Computer-Assisted Learning vs. Small Group Tutorials in Periodontal Charting: A Randomized Controlled Trial in a Malaysian Dental School
JOURNAL OF OROFACIAL SCIENCES 2019
a
Inhibition of protein glycation by tiger milk mushroom [Lignosus rhinocerus (Cooke) Ryvarden] and search for potential anti-diabetic activity-related metabolic pathways by genomic and transcriptomic data mining
FRONTIERS IN PHARMACOLOGY 2018
a
Molecular attributes and apoptosis-inducing activities of a putative serine protease isolated from Tiger Milk mushroom (Lignosus rhinocerus) sclerotium against breast cancer cells in vitro
PEERJ 2018
a
Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast
MICROBIAL CELL FACTORIES 2017
a
Nutrient composition, antioxidant properties, and anti‐proliferative activity of Lignosus rhinocerus Cooke sclerotium
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE 2015
a
Genome-based proteomic analysis of Lignosus rhinocerotis (Cooke) Ryvarden sclerotium
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES 2015
a
Shotgun proteomic analysis of tiger milk mushroom (Lignosus rhinocerotis) and the isolation of a cytotoxic fungal serine protease from its sclerotium
JOURNAL OF ETHNOPHARMACOLOGY 2015
a
Transcriptome analysis revealed highly expressed genes encoding secondary metabolite pathways and small cysteine-rich proteins in the sclerotium of Lignosus rhinocerotis
PLOS ONE 2015
a
DNA barcode markers for two new species of Tiger Milk Mushroom: Lignosus tigris and L. cameronensis
INTERNATIONAL JOURNAL OF AGRICULTURE AND BIOLOGY 2014
a
The genome of the Tiger Milk mushroom, Lignosus rhinocerotis, provides insights into the genetic basis of its medicinal properties
BMC GENOMICS 2014
a
Energy and nutritional composition of Tiger Milk Mushroom (Lignosus tigris Chon S. Tan) sclerotia and the antioxidant activity of its extracts
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES 2014
a
Nutrient composition, antioxidant properties, and anti‐proliferative activity of Lignosus rhinocerus Cooke sclerotium
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE 2013
a
Breathing new life to a Malaysia lost national treasure-the Tiger-Milk mushroom (Lignosus rhinocerotis)
MUSHROOM SCIENCE XVIII: PROCEEDINGS OF THE18TH CONGRESS OF THE INTERNATIONAL SOCIETY FOR MUSHROOM SCIENCE 2012
a
Isolation and characterization of the thrombin-like enzyme from Cryptelytrops albolabris (white-lipped tree viper) venom
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY PART B: BIOCHEMISTRY AND MOLECULAR BIOLOGY 2012
a
Resistance against tumour necrosis factor α apoptosis by the cellular prion protein is cell‐specific for oral, colon and kidney cancer cell lines
CELL BIOLOGY INTERNATIONAL 2012
a
Resistance against apoptosis by the cellular prion protein is dependent on its glycosylation status in oral HSC-2 and colon LS 174T cancer cells
CANCER LETTERS 2011
Other Publications
a
Potential Anticancer Peptides From Serine Protease Precursor of L. rhinocerus TM02®: An in silico approach
34ᵗʰ Malaysian Association of Clinical Biochemists Conference 2024 in collaboration with 2ⁿᵈ MyBiomed Symposium | 21 Jul 2024
a
Wound Healing Potential of Lignosus rhinocerus TM02®: Genomic Insights
Asian Regional Conference on Systems Biology 2023 | 21 Dec 2023
a
In vitro antibacterial screening of Lignosus rhinocerus TM02® (Tiger Milk Mushroom) extracts
The 46th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology | 24 Aug 2022
a
Apoptosis induction and immunomodulation in a human oral cancer cell line, ORL 204 by Lignosus rhinocerus TM02 ® via a proposed intervention of TNF signaling
MAHSA International Dentistry Conference 2022 | 24 Jun 2022
a
Polycystic Ovary Syndrome (POCS) and Periodontitis: A Blibliometric Analysis
MAHSA International Dentistry Conference 2021 | 24 Sep 2021
a
Anti-Cancer Property of Tiger Milk Mushroom in Selected Oral Cancer Cell Lines, 27th FAOBMB & 44th MSBMB Conference
27th FAOBMB & 44th MSBMB Conference | 19 Aug 2019
a
The Immunomodulation Property of Tiger Milk Mushroom and Its Cytotoxic Effect in Selected Oral Cancer Cell Lines
MAHSA Research Carnival | 22 Nov 2018
a
Analysis of Functional Mutations of Activation Function 1 of Progesterone Receptor in Mice
Basel Life, Congress Center Basel | 10 Sep 2017
a
Insights into the Genome of Lignosus Rhinocerotis (Cooke) Ryvarden
University of Malaya Researchers’ Conference (UMRC) 2013 | 19 Nov 2013
a
Evaluation of Antioxidant Activity of Lignosus rhinocerus (Tiger milk mushroom) sclerotia
The 18th Congress of the International Society for Mushroom Science | 26 Aug 2012
a
Molecular Phylogeny of Lignosus rhinocerus (Tiger Milk Mushroom) Based on Complete 18S and 28S Ribosomal DNA Sequences
The 18th Congress of the International Society for Mushroom Science | 26 Aug 2012
a
Evaluation of the Antioxidant Activity in Lignosus spp
36th Annual Conference of the MSBMB | 27 Jul 2011
a
Evaluation of the Proliferative and Anti-Apoptotic Properties of Cellular Prion Protein in Kidney, Oral and Colon Cancer Cell Lines
8th International Symposium of Health Sciences (i-SIHAT 2010) | 09 Dec 2010
a
Site-Directed Mutagenesis and Stable Overexpression of Alpha-Synuclein Mutations of Familial Parkinson's Disease in neuronal cell lines
34th Annual Conference of the MSBMB | 07 Oct 2009
Books
a
CRC Press (2022). Omics for Natural Products as Adjunct Nutrition
Patents
a
LIGNOSUS RHINOCEROTIS SERINE PROTEASE | 27 Jan 2015
a
MEDICINAL USE OF THE EXTRACT OF LIGNOSUS RHINOCEROTIS | 08 Apr 2013
Supervisions
a
Yeu Kai Zhe | Master (Mixed Mode) | 06 Dec 2022 - 20 Oct 2023
Thesis: The Effects of Blue Diode Laser 450nm and Red Diode Laser 650nm on Dentinal Surface: A Comparative In Vitro Study
a
Aliza Nur Shuhaili binti Azlan, Ellysa Leong Teng Shan, Janet Chai Pei Shan | Undergraduate | 04 Oct 2022
Thesis: A Clinical Investigation into the Dermal Application of L. rhinocerus TM02 Water Extract for Mouth Ulceration
a
Asha Sharma Pusnaa a/p S Narayanan, Tan Pei Ying, Tay Kit Ken | Undergraduate | 25 Nov 2021 - 17 May 2023
Thesis: Efficacy of Strawberry Juice, Pineapple Juice, and Honey Solution in Counteracting Extrinsic Teeth Staining by Coffee: An In Vitro Study
a
Aiman Muhamad Zulkiffili, Luqman Hakim Roslan, Nurul Husna Ilyana Azrin | Undergraduate | 01 Feb 2021 - 21 Jul 2022
Thesis: Assessment of Self-Perceived Malocclusion and Barriers to Orthodontic Treatment: A Cross-Sectional Study
a
Harveender Kaur | Master (Mixed Mode) | 02 Dec 2020 - 18 Nov 2021
Thesis: A Comparative Evaluation of Polymerization Shrinkage, Degree of Conversion, and Antibacterial Activity of Zirconia-Reinforced Rice Husk Nanohybrid Composite
a
Yusra Mahdi | Master (Mixed Mode) | 20 Dec 2019 - 17 Nov 2020
Thesis: The antimicrobial activity of Swietenia macrophylla extract on plaque biofilm: An in-situ study
a
Chan Zheng Wen, Ooi Pei Yun, Phuan Yi Fan | Undergraduate | 26 Nov 2019 - 22 Aug 2021
Thesis: An Assessment of Oral Cancer Knowledge, Attitudes, and Practices Among Undergraduate Students in Malaysian Dental Schools
a
Ng Min Jia | Doctorate | 12 Nov 2019
Thesis: IN VIVO ANTITUMOUR PROSPECT OF LIGNOSUS RHINOCERUS COOKE RYVARDEN AND MULTI-OMICS STUDY OF LIGNOSUS TIGRIS C. S. TAN
a
Sheryl Teo Jing Ning, Wan Nurul Hana binti Wan Mohamad Saleh | Undergraduate | 23 Nov 2018 - 28 Jun 2020
Thesis: Prevalence of Carpal Tunnel Syndrome Among Dentists in Klang Valley
a
Tan Kah Look, Lim Yin Ying | Undergraduate | 16 Nov 2018 - 01 Jun 2020
Thesis: In vitro cytotoxic and COX-2 inhibitory evaluation of tiger milk mushroom (Lignosus rhinocerus TM02) against a panel of human oral cancer cell lines