LIM CHOOI LING



Salutation
Associate Professor Dr

School/Centre
School of Health Sciences

Department
Applied Biomedical Science and Biotechnology

Appointment
Head of Division, Applied Biomedical Sciences and Biotechnology

Position
Associate Professor


Professional Network


Education

a
Postgraduate Certificate in Health Professions Education (Health Professions Education), 2023 IMU University
a
PhD (Immunobiology), 2010 Universiti Putra Malaysia
a
Bachelor of Science (Biomedical Science) Honours (Biomedical Science), 2006 Universiti Putra Malaysia

Memberships

a
Malaysian Biomedical Science Association (MyBiomed) Secretary 2016 - Present

Research Funding
a
Development and evaluation of immersive 360 virtual simulated scenarios for training and assessments in crime scene investigation IMU Internal Research Grant | 19 Sep 2024 - 31 Dec 2025
a
Effect of Microalgae Extracts on Ultraviolet (UV) Irradiation-Induced Damage in a Human Retinal Pigment Epithelium (RPE) Cell Line IMU Internal Research Grant | 01 Jun 2024 - 31 Dec 2024
a
Photoprotective Bioactivity of Microalgae Extracts on Ultraviolet Light-Irradiated Human Keratinocytes IMU Internal Research Grant | 01 Jun 2023 - 31 Dec 2023
a
The Role and Epigenetic Changes of Inhibitor of κB kinase α (IKKα) in a Pancreatic Ductal Adenocarcinoma (PDAC) Cell Line IMU Internal Research Grant | 01 Mar 2023 - 30 Sep 2023
a
Photoprotective Potential of Mycosporine-Like Amino Acids (MAAs) and Bioactive Compounds from Antarctic Microalgae on Human Keratinocytes IMU Internal Research Grant | 01 Mar 2023 - 28 Feb 2026
a
Impact of a standardised breakfast on clinical laboratory tests Bachelor of Science (Hons) in Biomedical Science | 01 Jun 2022 - 30 Nov 2022
a
Impact of a Malaysian breakfast on clinical laboratory tests Bachelor of Science (Hons) in Biomedical Science | 14 Jun 2021 - 18 Sep 2021
a
Activation of the GLI transcription factor by canonical hedgehog signaling and non-canonical pathways in colorectal cancer. IMU | 01 Aug 2020 - 01 Dec 2020
a
Canonical Hedgehog signaling in colorectal cancer IMU | 01 Jul 2020 - 01 Oct 2020
a
KRAS mutations in colorectal cancer and activation of the GLi transcription factor. IMU | 01 Jul 2020 - 01 Oct 2020
a
Role of p53 gain-of-function mutations in modulating the miR-200 family and epithelial-mesenchymal plasticity in breast epithelial cells IMU | 01 Feb 2020 - 01 Jul 2021
a
An Online Portal for a Blended Mentoring Program in the IMU- A Pilot Project IMU | 01 Nov 2019 - 01 Apr 2020
a
Evaluation of Clinical Chemistry Analytes in Haemolysed Blood Samples IMU | 01 Jul 2019 - 01 Jun 2020
a
Roles of Receptor Interacting Protein Kinase 1 in beta-Amyloid deposition mediated through autophagy in Alzheimer's disease IMU | 18 Aug 2018 - 18 Dec 2018
a
Induction of epithelial-mesenchymal (EMT) and mesenchymal-epithelial transition (MET) in breast cancer mammospheres and parental cell lines IMU | 01 Jul 2018 - 01 Jan 2019
a
Role of p53 Gain-of-function mutations R273H and R175H on Epithelial-Mesenchymal Plasticity (EMP) in Breast Cancer Cells FRGS | 01 Jan 2018 - 01 Dec 2018
a
Roles of Receptor Interacting Protein Kinase 1 in beta-Amyloid Deposition in Alzheimer’s Disease FRGS | 01 Aug 2016 - 31 Jan 2019
a
Reversal of age-related hyposalivation by upregulation of salivary gland aquaporins ERGS | 01 Jun 2013 - 31 Jul 2016
a
Epidermal growth factor receptor (EGFR)-mediated rescue of downregulated aquaporin 3 (AQP3) in ultra violet (UV)-irradiated human keratinocytes by edible birdnest (EBN) FRGS | 01 Apr 2011 - 01 Nov 2012

Publications

Research Articles

a
Focus: Chronic Disease: Natural Bioactive Compounds from Macroalgae and Microalgae for the Treatment of Alzheimer’s Disease: A Review THE YALE JOURNAL OF BIOLOGY AND MEDICINE 2024
a
Prospecting bioactivity in Antarctic algae: A review of extracts, isolated compounds and their effects FITOTERAPIA 2024
a
Neurotoxicity of nanoplastics: A review F1000RESEARCH 2024
a
THE ROLES OF ANTIFIBROTIC THERAPIES IN POST-SARS-CoV-2 INFECTION MALAYSIAN JOURNAL OF BIOCHEMISTRY & MOLECULAR BIOLOGY 2023
a
Are Fermented Foods Effective against Inflammatory Diseases? INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH 2023
a
Curcumin effect on Acanthamoeba triangularis encystation under nutrient starvation PEERJ 2022
a
Precision and advanced nano-phytopharmaceuticals for therapeutic applications NANOMATERIALS 2022
a
The Role of Monoamine Oxidase B Inhibitors in the Treatment of Parkinson’s Disease-An Update CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (FORMERLY CURRENT DRUG TARGETS-CNS & NEUROLOGICAL DISORDERS) 2022
a
An Overview of Herbal Medicines for Idiopathic Pulmonary Fibrosis PROCESSES 2022
a
Roles of receptor‐interacting protein kinase 1 in SH‐SY5Y cells with beta amyloid‐induced neurotoxicity JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 2022
a
Phytochemicals and Nano-Phytopharmaceuticals Use in Skin, Urogenital and Locomotor Disorders: Are We There? PLANTS 2022
a
Effects of Amyloid Precursor Protein Overexpression on NF-κB, Rho-GTPase and Pro-Apoptosis Bcl-2 Pathways in Neuronal Cells REPORTS OF BIOCHEMISTRY & MOLECULAR BIOLOGY 2021
a
An overview of complementary and alternative medicine for alzheimer's and parkinson's disease MALAYSIAN JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 2021
a
Peganum harmala Extract Has Antiamoebic Activity to Acanthamoeba triangularis Trophozoites and Changes Expression of Autophagy-Related Genes PATHOGENS 2021
a
Focus: Plant-based Medicine and Pharmacology: Antidiabetic Potential of Syzygium sp.: An Overview The Yale journal of biology and medicine 2020
a
Epithelial-mesenchymal plasticity—engaging stemness in an interplay of phenotypes Stem cell investigation 2019
a
Overview of the Pharmacological Activities of Aframomum melegueta. Pertanika Journal of Tropical Agricultural Science 2019
a
Natural products: Alternative therapeutic compounds against Acanthamoeba spp ASIAN J. PHARMACOGN 2019
a
Anticancer potential of Syzygium species: a review Plant Foods for Human Nutrition 2019
a
TARGETING AUTOPHAGY IN ALZHEIMER’S DISEASE: AN OVERVIEW MALAYSIAN JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY 2019
a
Role of p53 family isoforms in enhancing aggressiveness and chemoresistance in pancreatic cancer WORLD ACADEMY OF SCIENCES JOURNAL 2019
a
Receptor-Interacting Protein Kinase 1 (RIPK1) as a Potential Therapeutic Target: An Overview of Its Possible Role in the Pathogenesis of Alzheimer's Disease Current Alzheimer Research 2019
a
Niosomes: a review of their structure, properties, methods of preparation, and medical applications ASIAN BIOMED 2018
a
A mini review on phytochemical constituents and pharmacological activities of Adenium obesum Journal of Tropical Agricultural Science 2018
a
A Mini Review on Phytochemical Constituents and Pharmacological Activities of Adenium obesum. Pertanika Journal of Tropical Agricultural Science 2018
a
Functional roles of receptor interacting protein kinase 1 in Alzheimer's disease JOURNAL OF MEDICAL DISCOVERY 2017
a
Breast cancer stem cells—from origins to targeted therapy Stem cell investigation 2017
a
Soi Moi Chye ANNA PICK KIONG LING, RHUN YIAN KOH, NIOSOMES: A REVIEW OF THEIR STRUCTURE, PROPERTIES, METHODS OF PREPARATION, AND MEDICAL APPLICATIONS, ASIAN BIOMED (RES REV NEWS) 2017
a
Updates on Hepatic Stellate Cell Involvement in Liver Fibrosis JOURNAL OF MEDICAL DISCOVERY 2016
a
Antioxidant activity of the sea bird nest (Eucheuma cottonii) and its radical scavenging effect on human keratinocytes JOURNAL OF MEDICAL AND BIOENGINEERING 2015
a
Inhibition of transforming growth factor-β via the activin receptor-like kinase-5 inhibitor attenuates pulmonary fibrosis Molecular medicine reports 2015
a
Metabolites from Actinomyces strain H6552 extract inhibit transforming growth factor-mediated pulmonary fibrosis Tropical Journal of Pharmaceutical Research 2014
a
Bioactive molecules: current trends in discovery, synthesis, delivery and testing IEJSME 2013
a
Antioxidant and anti-proliferative activities of roselle juice on caov-3, mcf-7, mda-mb-231 and hela cancer cell lines AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY 2011
a
A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells Journal of Biological Chemistry 2010
a
A single nucleotide polymorphism of DDX5 that confers more rapid fibrosis progression is associated with reduced transcriptional repression of key fibrogenic genes in hepatic stellate cells HEPATOLOGY: 59TH ANNUAL MEETING OF THE AMERICAN ASSOCIATION FOR THE STUDY OF LIVER DISEASES 2008

Other Publications

a
Harnessing the Power of Fermented Foods: A New Frontier in Combating Inflammatory Diseases 7th Hunan International Conference for Innovation and Development of Biomedicine and Chinese Medicine (BioCM-7) | 29 Oct 2024
a
PHOTOPROTECTIVE BIOACTIVITY OF PSEUDOKIRCHNERIELLA SUBCAPITATA SPP. EXTRACTS ON ULTRAVIOLET LIGHT-IRRADIATED HUMAN KERATINOCYTES 34th MACB CONFERENCE IN CONJUNCTION WITH THE 2nd MYBIOMED SYMPOSIUM 2024 | 22 Jul 2024
a
EPIGENETIC CHANGES MODULATED BY INHIBITOR OF KAPPA B KINASE ALPHA (IKKα) IN A PANCREATIC DUCTAL ADENOCARCINOMA (PDAC) CELL LINE 34th MACB CONFERENCE IN CONJUNCTION WITH THE 2nd MYBIOMED SYMPOSIUM 2024 | 22 Jul 2024
a
Remedies from the Sea – Anti-Arthritic and Photoprotective Potential of Marine and Microalgae 6th Hunan International Conference for Innovation and Development of Biomedicine and Chinese Medicine (BioCM-6) | 01 Nov 2023
a
Mycosporine-Like Amino Acids (MAAs) – Natural Sunscreen from Marine Algae 3rd International Conference on Natural Products and Human Health – 2023 (ICNPHH-2023) | 09 Oct 2023
a
Empowering Teachers in Biomedicine Round Table - Current Challenges in Medical Education: Cultural and socio-economic differences in education | 30 Jan 2023
a
The Role Of P53 Gain-Of-Function Mutations In Modulating the Mir-200 Family And Epithelial-Mesenchymal Plasticity In Breast Epithelial Cells International Undergraduate Medical Research Conference 2021 (IUMRC21) | 02 Nov 2022
a
Fasting Versus Non-Fasting Blood Samples and Clinical Chemistry Analyte Levels – An Update Asia Pacific Consortium of Researchers and Educators, Inc. (APCoRE) 2021 Convention and International Conference | 08 Dec 2021
a
Hepatic Stellate Cells - Current Updates on Characterization, Mechanisms, and Role in Liver Fibrosis Management Asia Pacific Consortium of Researchers and Educators, Inc. (APCoRE) 2021 Convention and International Conference | 08 Dec 2021
a
Current Highlights on Covid-19 Associated Liver Pathology: A Review Asia Pacific Consortium of Researchers and Educators, Inc. (APCoRE) 2021 Convention and International Conference | 08 Dec 2021
a
Advances in the Modulation of Breast Cancer Stem Cell Plasticity by the MiR-200 Family Asia Pacific Consortium of Researchers and Educators, Inc. (APCoRE) 2021 Convention and International Conference | 08 Dec 2021
a
Fasting Interference on Lipid Profile: A Systematic Review International Undergraduate Medical Research Conference 2021 (IUMRC21) | 02 Nov 2021
a
Fasting Interference in Complete Blood Count Parameters: A Systematic Review International Undergraduate Medical Research Conference 2021 (IUMRC21) | 02 Nov 2021
a
Virtual Reality CSI – Examining Crime Scenes in Cyberspace 14th International Medical Education Conference (IMEC) | 12 Mar 2021
a
Attenuation of liver myofibroblast activation by a small-molecule TGF-beta receptor I inhibitor INTERNATIONAL SYMPOSIUM OF MOLECULAR MEDICINE | 06 Oct 2011
a
PHARMACOLOGIC INHIBITION OF ACTIVIN RECEPTOR-LIKE KINASES-5 BY SB 431542 ATTENUATES BLEOMYCIN-INDUCED PULMONARY FIBROSIS 15th Congress of the Asian Pacific Society of Respirology (APSR) | 22 Nov 2010


Supervisions
a
Chia Kiat Fatt | Doctorate | 01 Mar 2023 Thesis: Photoprotective Potential of Mycosporine-Like Amino Acids (MAAs) and Bioactive Compounds from Antarctic Microalgae on Human Keratinocytes
a
Parvinpal Kaur | Master (Mixed Mode) | 01 Mar 2023 Thesis: The Role and Epigenetic Changes of Inhibitor of κB kinase α (IKKα) in a Pancreatic Ductal Adenocarcinoma (PDAC) Cell Line
a
Wong Ming Hui | Undergraduate | 01 Jan 2023 - 31 Jul 2023 Thesis: Mechanism of nanoplastic-induced toxicity via apoptosis in a neuronal cell line
a
YEO YEE SHENG; MAISARAH NABILA BINTI MAZLAN; MAAISHA ABDUL WAHHAB; AHMAD NAQIUDDIN BIN AHMAD SOPHIEN | Undergraduate | 01 Jun 2022 - 31 Oct 2023 Thesis: Impact of a standardised breakfast on clinical laboratory tests
a
Wong Vickie | Undergraduate | 01 Sep 2020 - 31 Jul 2021 Thesis: Role of p53 gain-of-function mutations in modulating the miR-200 family and epithelial-mesenchymal plasticity in breast epithelial cells
a
Yee Zong Yang | Master (Research) | 01 Jan 2016 - 30 Sep 2021 Thesis: Role of p53 Gain-of-function mutations on Epithelial-Mesenchymal Plasticity (EMP) in Immortalised Human Mammary Epithelial Cell Lines MCF-10A and MCF-12A