THIN THIN WIN @ SAFIYA YUNUS



Salutation
Associate Professor Dr

School/Centre
School of Medicine

Department
Pathology

Appointment
Head of Department, Pathology & Pharmacology

Position
Associate Professor

Email
thinthinwin@imu.edu.my

Professional Network


Education

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Diploma in Medical Education (Medical Education), 2005 Institute of Medicine II, Yangon, Myanmar (Now University of Medicine II)
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Master of Pathology (Pathology), 1999 Institute of Medicine I, Yangon, Myanmar (Now University of Medicine I)
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M.B,B.S (Medicine), 1988 Institute of Medicine, Mandalay (Now University of Medicine, Mandalay)

Memberships

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Academy of Medicine Malaysia Member 2017 - Present
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International Academy of Pathology, Malaysian Division (IAPMD) Lifetime Member 2015 - Present

Research Funding
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Evaluation of the effectiveness of generative AI tools in creating high-quality case-based multiple-choice questions for three disciplines in a medical program. IMU Internal Research Grant | 01 Nov 2024 - 31 Aug 2025
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Overcoming Educational Barriers: Tailored Science Teaching for Grade 8 Refugee Students (IMU University & British Pharmacological Society initiative) IMU Internal Research Grant | 20 Sep 2024 - 19 Sep 2025
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Prognostic significance of dynamin-related protein 1 (Drp1) expression in cancers: A systematic review IMU Internal Research Grant | 01 Mar 2024 - 31 Jul 2024
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Vaccine-based immunotherapy in the management of human papillomavirus–associated squamous cell carcinoma: A systematic review and meta-analysis IMU Internal Research Grant | 02 Jan 2024 - 31 Dec 2024
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Study to elucidate the involvement of Drp1 signalling pathways in oestrogen-regulated mitochondrial dynamics in ER-positive breast cancer cell lines FRGS 2023-1 | 01 Nov 2023 - 31 Oct 2026
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Role of EGFR exon 20 insertion mutation in non-small cell lung carcinoma: An updated meta-analysis of prognostic factor studies IMU Internal Research Grant | 01 Jul 2023 - 30 Jun 2024
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Comparative study on the effects of two cooking processes on selected toxic heavy metal concentrations in selected varieties of commercially available fish and prawns consumed in Malaysia. IMU Internal Research Grant | 01 Jun 2023 - 31 Dec 2023
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Determination of the role of Dynamin-related protein 1 post-translational modification (phosphoDrp1) in ER-positive human breast cancer samples IMU Internal Research Grant | 10 Mar 2023 - 31 Dec 2024
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A systematic review of the association between diabetes mellitus and risk of gastrointestinal malignancies Bachelor of Pharmacy (Hons) | 01 Jun 2021 - 30 Nov 2021
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PD-L1 inhibitor, Atezolizumab in the treatment of triple-negative breast cancer: A systematic review and meta-analysis Bachelor in Medical Sciences (Hons) | 01 Jun 2021 - 31 May 2022
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Safety of PD-L1 Inhibitor (Atezolizumab) in Non-Small Cell Carcinoma Lungs: A Meta-analysis of Randomized Controlled Trials IMU | 01 Jul 2020 - 01 Oct 2020
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A systematic review and meta-analysis on immune checkpoint inhibitors for the treatment of advanced malignant melanoma: Monotherapy Vs combination therapy IMU | 01 Jul 2020 - 01 Jun 2021
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Polymorphisms of Toll-like receptors (TLRs 4 and 9) and the risk of severe falciparum malaria: A meta-analysis of genetic association studies IMU | 01 Jul 2020 - 01 Nov 2020
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Analysis of students’ satisfaction and effectiveness on light microscopy and virtual microscopy in teaching learning sessions of undergraduate medical course: A randomized cross-over trial study IMU | 01 Mar 2020 - 01 Feb 2021
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Association of Clinicopathological Parameters of Colorectal Cancer and Diabetes Mellitus: A Hospital Based Descriptive study IMU | 01 Feb 2020 - 01 Jul 2021
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An alternative nitric oxide-based strategy in protecting against experimental cerebral malaria FRGS 2019-1 | 01 Oct 2019 - 30 Sep 2024
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Role of aspirin in reducing risk of gastric cancer: A meta-analysis of duration of use response IMU | 01 Mar 2019 - 01 Sep 2019
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Development of an automated decision support tool for pancreatic diagnosis through fine needle aspirates using deep convolution neural network Internal IMU-Pancreatic Cancer Challenge Grant | 25 Feb 2019 - 31 May 2020
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The role of cytokines (Interleukin and tumour necrotic factors) and gene-gene interaction in Helicobacter pylori infected gastric cancer: A hospital based case control study FRGS 2018-1 | 03 Sep 2018 - 31 Aug 2024
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Investigation of Molecular Mechanisms of Antiatherosclerotic Effect of Labdane Diterpenoid Lactones of Andrographis Paniculata IMU | 01 Jul 2018 - 01 Dec 2018
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The Clinicopathological Spectrum of Lymphoid Neoplasms: A Hospital based Descriptive Study IMU | 01 Jan 2018 - 01 Nov 2018

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Publications

Research Articles

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The role of circular RNAs (circRNAs) as a prognostic factor in lung cancer: a meta-analysis BMC CANCER 2024
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Efficacy of neoadjuvant chemotherapy for locally invasive cervical cancer during pregnancy: An updated systematic review JOURNAL OF OBSTETRICS, GYNECOLOGY AND CANCER RESEARCH 2024
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Clinicopathological study of gastric cancer in a Malaysian tertiary public health care centre THE MEDICAL JOURNAL OF MALAYSIA 2023
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Surviving the COVID-19 Pandemic: Lessons Learnt and Experience of a Private Medical School in Malaysia Education in Medicine Journal 2023
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Combined atezolizumab and nab-paclitaxel in the treatment of triple negative breast cancer: a meta-analysis on their efficacy and safety BMC CANCER 2022
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Thymosin‐ɑ1 for people with chronic hepatitis B COCHRANE DATABASE OF SYSTEMATIC REVIEWS 2022
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Efficacy and Safety of Immune Checkpoint Inhibitors for Advanced Malignant Melanoma: A Meta-Analysis on Monotherapy Vs Combination Therapy JOURNAL OF CANCER 2022
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Polymorphisms of Tumour necrosis factor-α-308 (rs 1800629) and gastric cancer susceptibility: A meta-analysis of associations studies with trial sequential analysis Research Square 2021
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A 5-year clinicopathological study on microscopic colitis at a Malaysian tertiary hospital. THE MEDICAL JOURNAL OF MALAYSIA 2021
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Primary retroperitoneal serous adenocarcinoma: A case report of rare malignancy with literature review INDIAN JOURNAL OF CANCER 2021
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Aspirin and Reducing Risk of Gastric Cancer: Systematic Review and Meta-Analysis of the Observational Studies. JOURNAL OF GASTROINTESTINAL & LIVER DISEASES 2020
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Diagnostic Accuracy of Intraoperative Frozen Sections in the Diagnosis of Central Nervous System Lesions: A Hospital-Based Study IIUM MEDICAL JOURNAL MALAYSIA 2020
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An Analysis of the Student's Performance and Marking Process in Open-Ended Short Answer Questions in a Medical Programme: A Pilot Study. EDUCATION IN MEDICINE JOURNAL 2019
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Expression of vascular endothelial growth factor and its receptors in thyroid nodular hyperplasia and papillary thyroid carcinoma: a tertiary health care centre based study ASIAN PACIFIC JOURNAL OF CANCER PREVENTION: APJCP 2019
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Role of coaggregation in the pathogenicity and prolonged colonisation of Vibrio cholerae MEDICAL MICROBIOLOGY AND IMMUNOLOGY 2019
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Evaluation of chondroprotective activity of Channa striatus in rabbit osteoarthritis model BIOMED RESEARCH INTERNATIONAL 2019
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Poorly differentiated thyroid carcinoma: A hospital-based clinicopathological study and review of literature INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY 2017
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Bilateral ovarian clear cell carcinoma arising in 17 year longstanding history of bilateral ovarian endometriosis IRANIAN JOURNAL OF PATHOLOGY 2016
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Osteosarcoma of The Talus: A Rare Location of the Tumour with Literature Review ANNALS OF PATHOLOGY AND LABORATORY MEDICINE 2016
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Association of E-Cadherin and β-Catenin with Clinicopathological Parameters in Primary Ovarian Surface Epithelial Carcinoma: A Hospital Based Immunohistochemical Study INTERNATIONAL MEDICAL JOURNAL 2016
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Epidermal Regeneration of Cultured Autograft, Allograft, and Xenograft Keratinocytes Transplanted on Full-Thickness Wounds in Rabbits. EXPERMENTAL AND CLINICAL TRANSPLATATION 2015
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Dual Malignancies in a Monodermal Teratoma of the Ovary: A Rare Entity. INTERNATIONAL MEDICAL JOURNAL 2015
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Immunohistochemical Study of Apoptotic Related Proteins and Their Correlation with Clinicopathological Parameters in Liposarcoma INTERNATIONAL MEDICAL JOURNAL 2014
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Relationship of angiogenic and apoptotic activities in soft-tissue sarcoma SOUTH ASIAN JOURNAL OF CANCER 2014
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Congenital mature cystic teratoma of the lateral neck presenting as cystic hygroma: a rare case report with literature review TURK PATOLOJI DERG 2014
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Apoptotic activities in soft tissue sarcoma: immunohistochemical study and their association with tumour characteristics THE MALAYSIAN JOURNAL OF MEDICAL SCIENCES: MJMS 2013
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Solid variant of papillary thyroid carcinoma in a 14-year-old girl CASE REPORTS 2013
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Solitary posterior triangle neck mass as the rare sole presentation of papillary thyroid carcinoma BANGLADESH JOURNAL OF OTORHINOLARYNGOLOGY 2012
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Strongyloides stercoralis induced bilateral blood stained pleural effusion in patient with recurrent non-Hodgkin lymphoma TROPICAL BIOMEDICINE 2011

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Other Publications

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Gynaecological Cytopathology Diagnostic Lecture Series 2018: Essential of Cytology | 05 Jul 2018
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General Pathology for MOG Part I 1st Conjoin MOG Part I Intensive course | 27 Feb 2011
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Communication Skill in Medical Education Medical Education Workshop for new academic staff | 04 Nov 2005


Supervisions
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Munem Azad | Undergraduate | 01 Jul 2023 - 30 Jun 2024 Thesis: Role of EGFR exon 20 insertion mutation in non-small cell lung carcinoma: An updated meta-analysis of prognostic factor studies
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Nik Raimy Danial Bin Nik Hishamuddin, Jason Yap, Joachim Tan Wei Hong | Undergraduate | 01 Jun 2023 - 31 Dec 2023 Thesis: Comparative study on the effects of two cooking processes on selected toxic heavy metal concentrations in selected varieties of commercially available fish and prawns consumed in Malaysia.
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Leong Wen Kang | Undergraduate | 10 Mar 2023 - 31 Dec 2024 Thesis: Determination of the role of Dynamin-related protein 1 post-translational modification (phosphoDrp1) in ER-positive human breast cancer samples
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Sanabil Ahsan | Undergraduate | 01 Jul 2022 Thesis: Role of circular RNAs (CircRNAs) as a prognostic factor in lung cancer: A meta-analysis.
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Sharmni Vishnu K | Undergraduate | 01 Jul 2021 - 30 Jun 2022 Thesis: PD-L1 inhibitor, Atezolizumab in the treatment of triple-negative breast cancer: A systematic review and meta-analysis
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Liau Chee Siang; Ryan Pee Chiun Lay; Lee Ching Wann; Chan Kai Xin. | Undergraduate | 01 Jan 2021 - 31 Dec 2021 Thesis: A systematic review of the association between diabetes mellitus and risk of gastrointestinal malignancies
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Jnaneshwari Pradeep | Undergraduate | 01 Jul 2020 - 30 Jun 2021 Thesis: A systematic review and meta-analysis on immune checkpoint inhibitors for the treatment of advanced malignant melanoma: Monotherapy Vs combination therapy
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Mathangi Devindran | Undergraduate | 01 Jul 2020 - 30 Jun 2021 Thesis: Association of clinicopathological parameters of colorectal cancer and diabetes mellitus: A hospital based descriptive study.
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Danushka Terence Ravin De Silva | Undergraduate | 01 Jul 2019 - 30 Jun 2020 Thesis: Polymorphisms of Toll-like receptors (TLRs 4 and 9) and the risk of severe falciparum malaria: A meta-analysis of genetic association studies
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Dr. Htet Htet | Doctorate | 01 Jul 2019 Thesis: The role of cytokines (interluekin and tissue necrosis factors) and the gene-gene interaction in Helicobacter pylori infected gastric cancer: A hospital-based case-control study.
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Cheng Ong Fei, Joyce Lau Chui Fern | Undergraduate | 01 Jan 2019 - 31 Dec 2019 Thesis: Role of aspirin in reducing risk of gastric cancer: A meta-analysis of dose response
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Wong Jing Tong | Undergraduate | 01 Jan 2019 - 31 Dec 2019 Thesis: Safety of PD-L1 inhibitor (Atezolizumab) in non-small cell lung cancer: A meta-analysis of randomized controlled trail
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Wong Yieng Yii, Kee Pei Yi, Emily Lau Hie Yien, Janice Ting Shen Ling | Undergraduate | 01 Jan 2018 - 31 Dec 2018 Thesis: TR-013A, a Novel 11β-HSD1 Inhibitor: Investigations on MAPK, Apoptosis Signaling, oxidative stress and tissue remodeling in Cardiac tissue and Liver tissue remodeling in high fat diet/STZ- Induced Type-2 Diabetes Mellitus Mice
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Ling Wen Shi, Chan Jun Yi, Chooi Kien, Chang Jing Jing | Undergraduate | 01 Jan 2018 - 31 Dec 2018 Thesis: Investigation of molecular mechanisms of anti-atherosclerotic effect of Labdane diterpenoid lactones of Andrographis paniculata
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Dr. Raja Zubaidah Raja Mohd Rasi | Master (Mixed Mode) | 01 Apr 2014 - 31 Mar 2017 Thesis: Comparative study of accuracy of thyroid FNAC between conventional reporting system and Bethesda reporting system
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Ms. Nor laily Binti Hanifi | Master (Research) | 03 Feb 2014 - 31 Dec 2016 Thesis: In- vitro & In-vivo study of primary epidermal auto, allo, and xenografts transplanted onfull thickness wound in Oryctolagus cuniculus
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Dr. Nur Hidayati Mohamad Fakarul Razy | Master (Mixed Mode) | 01 Apr 2013 - 31 Aug 2016 Thesis: Expression of Epidermal growth factor (EGF), vasculoendothelial growth factor (VEGF)and their receptors in thyroid nodular hyperplasia, papillary thyroid carcinoma (PTC) and PTC in underlying nodular hyperplasia.
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Dr Yusoff Sharizal | Master (Mixed Mode) | 03 May 2010 - 01 May 2012 Thesis: The effects of malathion exposure on cerebellum of female rats: an immunohistochemical study
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Dr Wan Syazli Rodzaian bin Wan Ahmad Kamal | Master (Mixed Mode) | 05 Apr 2010 - 02 Apr 2012 Thesis: A comparative study between different ischaemic times during intra-operative transfer of free vascularized bone graft based on the Genicular artery in rabbits
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Dr Haider K. Abd Al-Abbas | Master (Mixed Mode) | 06 Apr 2009 - 30 Apr 2011 Thesis: Associaton between apoptotic related proteins and clinicopathological parameters in liposarcoma
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Dr. Yusri Yusuf | Master (Mixed Mode) | 07 Apr 2008 - 01 Apr 2011 Thesis: Expression of Angiogenetic markers and Apoptotic markers in soft tissue sarcomas

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