LIM LAY CHENG
Salutation
Dr
School/Centre
School of Pharmacy
Department
Life Sciences
Position
Senior Lecturer
Email
Education
a
PhD (Molecular Medicine), 2015
UKM Medical Molecular Biology Institute (UMBI)
a
Master (Medical Science (Biochemistry)), 2007
Universiti Kebangsaan Malaysia
a
BSc (Molecular Biology, Honours (Biochemistry)), 2004
Universiti Kebangsaan Malaysia
Memberships
a
Malaysian Proteomics Society (MAPS)
Co-Opted Committee Member
2021 - 2023
a
Persatuan Alumni UKM Medical Molecular Biology Institute
Vice-President (2020 - 2022), Committee (2023 - Present)
2020 - Present
Research Funding
a
Membrane proteome profiling on primary pancreatic ductal adenocarcinoma (PDAC) cell lines
IMU Internal Research Grant | 01 Jan 2024 - 31 Oct 2024
a
Membrane proteome profiling on metastatic pancreatic ductal adenocarcinoma (PDAC) cell lines
IMU Internal Research Grant | 01 Sep 2023 - 30 Jun 2024
a
Spatial mapping and proteogenomic characterization of tumour subclones in pancreatic ductal adenocarcinoma
FRGS | 01 Nov 2020 - 30 Apr 2024
a
Spatial proteome profiling of distinct cancer cell subpopulations within pancreatic ductal adenocarcinoma (PDAC): A pilot study
BMedScience Project | 03 Feb 2020 - 31 Jul 2021
a
Pancreatic ductal adenocarcinoma tumour subclones anatomy by spatial proteome mapping: A pilot study
IMU Staff Fund | 03 Jun 2019 - 30 Jun 2022
a
Identification of cancer testis antigens (CTAs) in pancreatic cancer: The search for potential immunotherapeutic targets
BMedScience Project | 01 Feb 2019 - 30 Sep 2019
a
The influence of pancreatic ductal adenocarcinoma (PDA) cells and pancreatic stellate cells (PSC) on myeloid derived suppressor cells (MDSC) immunosuppressive properties
FRGS | 01 Jan 2019 - 01 Jan 2023
Publications
Research Articles
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Single‐cell proteomics by mass spectrometry: Advances and implications in cancer research
PROTEOMICS 2024
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Effects of house-cultivated edible bird’s nest on immunoglobulin and cytokine release in vitro
VETERINARY WORLD 2024
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EtOH-LN cryoembedding workflow to minimize freezing artifact in frozen tissues: A pilot study in preparing tissues compatible with mass spectrometry-based spatial proteomics application
CRYOBIOLOGY 2023
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Molecular tissue profiling by MALDI imaging: recent progress and applications in cancer research
Critical Reviews in Clinical Laboratory Sciences 2021
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Perspectives and advancements in the design of nanomaterials for targeted cancer theranostics
Chemico-biological interactions 2020
a
Gene therapy and type 1 diabetes mellitus
Biomedicine & Pharmacotherapy 2018
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Proteome heterogeneity in colorectal cancer
Proteomics 2018
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Identification of differentially expressed proteins in the serum of colorectal cancer patients using 2D-DIGE proteomics analysis
Pathology & Oncology Research 2016
Other Publications
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Spatial Proteome Mapping of Annotated Tumour Regions in Pancreatic Ductal Adenocarcinoma Tissues Reveals Eight Distinct Tumour Subpopulations
HUPO 2023 Congress | 17 Sep 2023
a
SPATIAL PROTEOME PROFILING OF DISTINCT CANCER CELL SUBPOPULATIONS WITHIN PANCREATIC DUCTAL ADENOCARCINOMA (PDAC): A PILOT STUDY
International Undergraduate Medical Research Conference (IUMRC) 2021 | 02 Nov 2021
a
Expression and clinical significance of cytochrome c oxidase subunit Vib polypeptide 2 (COX6B2) and CKLF-like MARVEL transmembrane domain-containing protein 2 (CMTM2) in PDAC tumour
10th Asia-Oceania Human Proteome Organization Congress | 30 Jun 2021
a
E f f e c t o f E d i b l e B i r d ’ s N e s t E x t r a c t on Cytokines Product ion in Human Immuni ty Choong
24th IUBMB Congress & 15th FAOBMB Congress (IUBMB Seoul 2018) | 04 Jun 2018
a
Establishment of the modular immune in vitro construct (MIMIC) to evaluate the effect of edible bird’s nest on human immunity
Universiti Tunku Abdul Rahman Inaugural FMHS Scientific Meeting 2017 | 25 May 2017
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Effect of edible-bird nest (EBN) on global gene and protein expression of Wharton’s Jelly.
3rd Edible Bird Nest Industry Conference (EBNIC) 2016: Empowering the essence of edible bird nest | 11 Oct 2016
a
Cancer proteomics for biomarker discovery
Centre for Cancer Research Monthly Seminar, University of Tunku Abdul Rahman | 18 May 2016
a
Serum proteomics-based identification of differentially expressed proteins in colorectal cancer.
1st National Conference for Cancer Research & 5th Regional Conference on Molecular Medicine (RCMM) | 08 Nov 2013
a
Serum proteomics-based identification of differentially expressed proteins in colorectal cancer
Asia-Pacific Journal of Molecular Medicine | 01 Jan 2013
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Comparative serum proteomic and pathway analysis reveals potential candidate biomarkers in colorectal cancer
4th Regional Conference on Molecular Medicine 2011 | 09 Oct 2011
a
Effect of age on erythrocyte antioxidant enzymes and plasma vitamin levels.
Proceedings of the 14th biennial meeting of the Society for Free Radical Research International | 18 Oct 2008
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Effect of age on antioxidant status and oxidative stress markers among Malays in Klang Valley
6th Costam/SFRR (Asean/Malaysia) International Workshop, Kuching, Sarawak | 29 Jun 2006
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Age-related changes in antioxidant enzymes activities in subjects from Klang Valley and Terengganu populations
Regional Conference on Molecular Medicine 2005 organized by UKM Medical Molecular Biology Institute (UMBI) | 09 Sep 2005
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The effect of age on catalase and superoxide dismutase enzymes activities among Malaysians
29th Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology | 28 Sep 2004
Supervisions
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Yoshana a/p Muruganand | Undergraduate | 01 Jan 2024 - 31 Oct 2024
Thesis: Membrane proteome profiling on primary pancreatic ductal adenocarcinoma (PDAC) cell lines
a
Alex Lee Wei Yan | Master (Coursework) | 01 Sep 2023 - 30 Jun 2024
Thesis: Membrane proteome profiling on metastatic pancreatic ductal adenocarcinoma (PDAC) cell lines
a
Tan Yong Chiang | Doctorate | 01 Nov 2020 - 30 Apr 2024
Thesis: Spatial mapping and proteogenomic characterization of tumour subclones in pancreatic ductal adenocarcinoma
a
Naili Hanani | Undergraduate | 03 Feb 2020 - 31 Jul 2021
Thesis: Spatial proteome profiling of distinct cancer cell subpopulations within pancreatic ductal adenocarcinoma (PDAC): A pilot study
a
Goh Jin Pin | Undergraduate | 01 Feb 2019 - 30 Sep 2019
Thesis: Identification of cancer testis antigens (CTAs) in pancreatic cancer: The search for potential immunotherapeutic targets
a
Chong Yuen Ping | Master (Research) | 01 Jan 2019 - 01 Jan 2023
Thesis: The influence of pancreatic ductal adenocarcinoma (PDA) cells and pancreatic stellate cells (PSC) on myeloid derived suppressor cells (MDSC) immunosuppressive properties