TAN BOON HOOI



Salutation
Dr

School/Centre
School of Health Sciences

Department
Applied Biomedical Science and BiotechnologyMedical Biotechnology

Position
Senior Lecturer




Education

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Doctor of Philosophy (PhD-Med), 2015 Monash University Malaysia
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Master of Science (Genetic Engineering and Molecular Biology), 2009 Universiti Putra Malaysia
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Bachelor of Science (Hons) (Biomedical Sciences), 2003 Universiti Putra Malaysia

Memberships

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Malaysian Society for Biochemistry and Molecular Biology | National | Member
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Malaysia Board of Technologists (MBOT) | National | Graduate Technologists (GT)
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Malaysian Society for Biochemistry and Molecular Biology | National | Member

Publications

Research Articles

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Cytochromes P450: Role in Carcinogenesis and Relevance to Cancers. CURRENT DRUG METABOLISM | 2022
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Molecular docking studies on the inhibitory selectivity of cytochrome P450 2C9 by natural anti-arthritic compounds N/A | 2022
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In vitro inhibitory effects of glucosamine, chondroitin and diacerein on human hepatic CYP2D6 DRUG METABOLISM AND PERSONALIZED THERAPY | 2021
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The CYP2R1 Enzyme: Structure, Function, Enzymatic Properties and Genetic Polymorphism JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES | 2021
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Expression of cytochrome P450 2C9 (CYP2C9) in Escherichia coli and its functional characterization ASIA-PACIFIC JOURNAL OF MOLECULAR BIOLOGY AND BIOTECHNOLOGY | 2019
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Cytochrome P450 genotype‐guided drug therapies: an update on current states CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY | 2018
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Cytochrome P450 2C9‐natural antiarthritic interactions: Evaluation of inhibition magnitude and prediction from in vitro data BIOPHARMACEUTICS & DRUG DISPOSITION | 2018
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Prevalence, virulence genes and antimicrobial resistance profiles of Salmonella serovars from retail beef in Selangor, Malaysia FRONTIERS IN MICROBIOLOGY | 2018
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In vitro and in silico approaches to study cytochrome P450-mediated interactions JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES | 2017
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The use of natural remedies to treat osteoarthritis CELLMED | 2016
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Molecular characterization of a recombinant manganese superoxide dismutase from Lactococcus lactis M4 BIOMED RESEARCH INTERNATIONAL | 2014

Other Publications

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Exploring the Inhibitory Effect of Osmanthus Flower Aqueous Extracts on Human Cytochrome P450 (CYP) through in vitro and in silico Approaches 33rd Intervarsity Biochemistry Seminar | 09 Dec 2023
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Establishment of a high-throughput fluorescence-based assay for in vitro catalytic activity of cytochrome P450 2D6 The 8th International Conference on Biomedical Engineering and Biotechnology | 22 Oct 2019
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EXPRESSION OF A RECOMBINANT HUMAN HEPATIC CYTOCHROME P450 3A4 IN ESCHERICHIA COLI – OPTIMISATION OF THE INDUCTION TIME International Conference on Biochemistry, Molecular Biology and Biotechnology | 15 Aug 2018
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Optimisation of the expression temperature of a recombinant human hepatic cytochrome P450 3A4 International Conference on Biochemistry, Molecular Biology and Biotechnology | 15 Aug 2018
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Effects of glucosamine, chondroitin and diacerein on human hepatic cytochrome P450 3A4 activity in vitro The XIII International Congress of Toxicology | 30 Jun 2013

Books

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Jenny Stanford Publishing (2019). Cytochromes P450, Cardiovascular Homeostasis and Disease


Supervisions
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Ng Aivon | Undergraduate | 01 Dec 2017 - 31 May 2018 Thesis: OPTIMIZING THE INDUCTION TIME FOR THE EXPRESSION OF A RECOMBINANT HUMAN HEPATIC CYTOCHROME P450 (CYP) IN ESCHERICHIA COLI
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Ong Bee Chia | Undergraduate | 01 Dec 2017 - 31 May 2018 Thesis: OPTIMIZING THE EXPRESSION TEMPERATURE OF A RECOMBINANT HUMAN HEPATIC CYTOCHROME P450 IN ESCHERICHIA COLI
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Choy Sze Mun | Undergraduate | 01 Dec 2018 - 31 May 2019 Thesis: THE EFFECT OF CYTOCHROME P450 (CYP) 2D6*1 AND *10 ON THE INHIBITORY POTENCY OF SERTRALINE AND PHENYTOIN.
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Lim Kai Shen | Undergraduate | 01 Dec 2018 - 31 May 2019 Thesis: The effect of cytochrome P450 (CYP) genetic polymorphism on inhibitory potency of phenytoin and sertraline
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Chong Ce Lynn | Undergraduate | 01 Dec 2018 - 31 May 2019 Thesis: The Effect of Cytochrome P450(CYP) 2D6 Allele 10 and Allele 14A on Inhibitory Potency of Sertraline
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Lau Rui Ying | Undergraduate | 01 Jun 2019 - 31 Oct 2019 Thesis: In vitro inhibitory effects of CYP3A4 activity by Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action
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Sandra Khoo Su Min | Undergraduate | 01 Jun 2019 - 31 Oct 2019 Thesis: In vitro inhibitory effects of CYP2C9 activity by Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action
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Ng Si Shun | Undergraduate | 01 Jun 2019 - 31 Oct 2019 Thesis: In vitro inhibitory effects of CYP2D6 activity by Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action
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Phang Jia Chern | Undergraduate | 01 Jun 2019 - 31 Oct 2019 Thesis: In vitro inhibitory effects of CYP1A2 activity by Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action
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Dhirmall A/L Selvakumar | Undergraduate | 01 Apr 2019 - 30 Nov 2019 Thesis: In vitro functional characterisation of human cytochrome P450 2A13 (CYP2A13) variants involved in coumarin hydroxylase activity
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Gan Su Ee | Undergraduate | 10 Jul 2023 - 30 Nov 2023 Thesis: Evaluation of cytochrome P450 inhibition potential of Ag8, a silver-N-heterocyclic carbene compound with promising anti-cancer action: in vitro and in silico study
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Leong Khai Qian | Undergraduate | 01 Jun 2023 - 31 Dec 2023 Thesis: THE INHIBITORY EFFECT OF OSMANTHUS FLOWER ETHANOL EXTRACT ON HUMAN CYTOCHROME P450 3A4 (CYP3A4) AND CYTOCHROME P450 2C9 (CYP2C9)
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Rachelle Chin Yun Yeen | Undergraduate | 01 Jun 2023 - 31 Dec 2023 Thesis: THE INHIBITORY EFFECT OF OSMANTHUS FLOWER AQUEOUS EXTRACT ON HUMAN CYTOCHROME P450 2C9 (CYP2C9) AND 3A4 (CYP3A4)