Mallikarjuna Rao Pichika



Salutation
Professor

School/Centre
School of Pharmacy

Department
Pharmaceutical Chemistry

Appointment
Head, Centre For Bioactive Molecules And Drug Delivery

Position
Professor

Email
mallikarjunarao@imu.edu.my

Professional Network


Education

a
Doctor of Phiolosophy (PhD) from faculty of Pharmaceutical Sciences (Pharmaceutical Sciences), 1999 Andhra University
a
Master of Pharmaceutical Sciences (Specialisation: Pharmaceutical Chemistry) (Pharmaceutical Sciences), 1995 Andhra University
a
Bachelor of Pharmaceutical Sciences (Pharmaceutical Sciences), 1993 Andhra University

Memberships

a
American Chemical Society | International | Member
a
Royal Society of Chemistry, UK | International | Fellow

Publications

Research Articles

a
Synthesis and Characterisation of Flavonoid Mannich Bases and the Evaluation of their Cytotoxic Activity LETTERS IN ORGANIC CHEMISTRY | 2024
a
Anti-inflammatory and anti-oxidative activities of andrographolide determined using atherosclerosis induced mice NATURAL AND APPLIED SCIENCES INTERNATIONAL JOURNAL (NASIJ) | 2024
a
Newly discovered clouting interplay between matrix metalloproteinases structures and novel quaternary Ammonium K21: computational and in-vivo testing BMC ORAL HEALTH | 2024
a
Swietenine Alleviates Nonalcoholic Fatty Liver Disease in Diabetic Mice via Lipogenesis Inhibition and Antioxidant Mechanisms ANTIOXIDANTS | 2023
a
Advancements in dextran-based nanocarriers for treatment and imaging of breast cancer INTERNATIONAL JOURNAL OF PHARMACEUTICS | 2023
a
In-vitro evaluation of the effectiveness of polyphenols based strawberry extracts for dental bleaching SCIENTIFIC REPORTS | 2023
a
Artificial intelligence in drug discovery and development DRUG DISCOVERY AND EVALUATION: SAFETY AND PHARMACOKINETIC ASSAYS | 2023
a
Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability ANTIOXIDANTS | 2023
a
Cathepsin-K inhibition enhances anti-cancerous activity within oral squamous cell carcinoma cells: Uncloaking the potency of new K21 formulation EXPERIMENTAL CELL RESEARCH | 2023
a
Antimicrobial FiteBac® K21 promotes antimicrobial Potency and wound healing HELIYON | 2023
a
Synthesis and Anti‐Inflammatory Activity of 2‐Amino‐4, 5, 6, 7‐tetrahydrobenzo [b] thiophene‐Derived NRF2 Activators CHEMISTRYOPEN | 2022
a
PH Responsive Polyurethane for the Advancement of Biomedical and Drug Delivery. Polymers 2022, 14, 1672 N/A | 2022
a
21st Century Pharmacy Education: Approaches To Curriculum Redesigning JOURNAL OF POSITIVE SCHOOL PSYCHOLOGY | 2022
a
Kinetics of Killing and Mode of action of Cinnamomum impressicostatum crude stem–bark extract on Methicillin Resistant Staphylococcus aureus AFRICAN JOURNAL OF BIOMEDICAL RESEARCH | 2022
a
SIMPLE HPLC METHOD FOR THE QUANTIFICATION OF GINGEROLS (4-, 6-, 8-, AND 10-) AND SHOGAOLS (6-, 8-, AND 10-) IN Zingiber officinale var. rubrum SUPERCRITICAL CARBON DIOXIDE (SC-CO2) EXTRACT RASAYAN JOURNAL OF CHEMISTRY | 2022
a
Quercetin and metformin synergistically reverse endothelial dysfunction in the isolated aorta of streptozotocin-nicotinamide-induced diabetic rats SCIENTIFIC REPORTS | 2022
a
Light-responsive polyurethanes: classification of light-responsive moieties, light-responsive reactions, and their applications RSC ADVANCES | 2022
a
Anti-Inflammatory Effects of Auranamide and Patriscabratine—Mechanisms and In Silico Studies MOLECULES | 2022
a
Synthesis and Incorporation of Quaternary Ammonium Silane Antimicrobial into Self‐Crosslinked Type I Collagen Scaffold: A Hybrid Formulation for 3D Printing DENTAL MATERIALS | 2022
a
Biochemical changes and macrophage polarization of a silane-based endodontic irrigant in an animal model SCIENTIFIC REPORTS | 2022
a
PH Responsive Polyurethane for the Advancement of Biomedical and Drug Delivery POLYMERS | 2022
a
Effect of Sustained Systemic Administration of Ginger (Z officinale) Rhizome Extracts on Salivary Flow in Mice INTERNATIONAL DENTAL JOURNAL | 2022
a
Success stories of AI in drug discovery-where do things stand? EXPERT OPINION ON DRUG DISCOVERY | 2022
a
Zingiber officinale var. rubrum: Red ginger’s medicinal uses MOLECULES | 2022
a
In vitro methods used for discovering plant derived products as wound healing agents–An update on the cell types and rationale FITOTERAPIA | 2021
a
Synthesis of quinozilinium fluoroborate salts from harmine CARBON LETTERS | 2021
a
Melastoma malabathricum L.: a review of its traditional uses, phytochemical constituents and bioactivities. N/A | 2021
a
Molecular Dynamic Simulation Search for Possible Amphiphilic Drug Discovery for Covid-19 MOLECULES | 2021
a
Concentration-Dependent Multi-Potentiality of L-Arginine: Antimicrobial Effect, Hydroxyapatite Stability, and MMPs Inhibition MOLECULES | 2021
a
The role of DMPK science in improving pharmaceutical research and development efficiency DRUG DISCOVERY TODAY | 2021
a
Antibacterial and antibiofilm efficacy of k21-E in root canal disinfection DENTAL MATERIALS | 2021
a
Swietenine potentiates the antihyperglycemic and antioxidant activity of Metformin in Streptozotocin induced diabetic rats Biomedicine & Pharmacotherapy | 2021
a
Effect of Propolis Nanoparticles against Enterococcus faecalis Biofilm in the Root Canal Molecules | 2021
a
Microarray analysis of the genomic effect of eugenol on methicillin resistant Staphylococcus aureus Molecules | 2021
a
Synthesis and anticancer evaluation of amide derivatives of imidazo-pyridines Medicinal Chemistry Research | 2021
a
Investigation of hyperbranched Poly (glycerol esteramide) as potential drug carrier in solid dispersion for solubility enhancement of lovastatin Journal of Drug Delivery Science and Technology | 2021
a
Hyperbranched poly (glycerol esteramide): A biocompatible drug carrier from glycerol feedstock and dicarboxylic acid Journal of Applied Polymer Science | 2021
a
Design, synthesis, anticancer evaluation and molecular docking studies of chalcone linked pyrido [4, 3-b] pyrazin-5 (6H)-one derivatives Journal of Molecular Structure | 2021
a
Studies on the mechanism of anti-inflammatory action of swietenine, a tetranortriterpenoid isolated from Swietenia macrophylla seeds PHYTOMEDICINE PLUS | 2021
a
PLGA nanoparticles loaded with quaternary ammonium silane and riboflavin for potential applications in adhesive dentistry International Journal of Adhesion and Adhesives | 2021
a
Novel approaches for the treatment of pulmonary tuberculosis Pharmaceutics | 2020
a
New Alkyl (E)-5-(Methylsulfinyl) Pent-4-Enoates from Raphanus sativus Seeds Revista Brasileira de Farmacognosia | 2020
a
Folic Acid Conjugated Nanocarriers for Efficient Targetability and Promising Anticancer Efficacy for Treatment of Breast Cancer: A Review of Recent Updates Current pharmaceutical design | 2020
a
A critical review on emerging trends in dry powder inhaler formulation for the treatment of pulmonary aspergillosis Pharmaceutics | 2020
a
New antimicrobial and collagen crosslinking formulated dentin adhesive with improved bond durability Journal of the mechanical behavior of biomedical materials | 2020
a
Novel riboflavin/VE-TPGS modified universal dentine adhesive with superior dentine bond strength and self-crosslinking potential Dental Materials | 2020
a
Multiscale in-vitro analysis of photo-activated riboflavin incorporated in an experimental universal adhesive Journal of the mechanical behavior of biomedical materials | 2020
a
A quaternary ammonium silane antimicrobial triggers bacterial membrane and biofilm destruction Scientific reports | 2020
a
Artificial intelligence in drug development: present status and future prospects Drug discovery today | 2019
a
Rising horizon in circumventing multidrug resistance in chemotherapy with nanotechnology MATERIALS SCIENCE AND ENGINEERING: C | 2019
a
A comprehensive review on eugenol's antimicrobial properties and industry applications: A transformation from ethnomedicine to industry PHARMACOGNOSY REVIEWS | 2019
a
Bioactive 2-(methyldithio) pyridine-3-carbonitrile from Persian shallot (Allium stipitatum Regel.) exerts broad-spectrum antimicrobial activity Molecules | 2019
a
Construction of a novel quinoxaline as a new class of Nrf2 activator BMC chemistry | 2019
a
Comparative efficacy of vanilloids in inhibiting toll-like receptor-4 (TLR-4)/myeloid differentiation factor (MD-2) homodimerisation Food & function | 2018
a
Edible foxtail millet flour stabilises and retain the in vitro activity of blueberry bioactive components. N/A | 2018
a
Galangin's potential as a functional food ingredient. N/A | 2018
a
tert-Butylhydroperoxide-Mediated Oxidation of Carbazole-3-carboxyaldehydes Synlett | 2018
a
Antifungal and antibiofilm activity of Persian shallot (Allium stipitatum Regel.) against clinically significant Candida spp TROP. BIOMED | 2018
a
One‐pot synthesis of cobalt‐incorporated polyglycerol ester as an antimicrobial agent for polyurethane coatings Journal of Applied Polymer Science | 2018
a
Edible foxtail millet flour stabilises and retain the in vitro activity of blueberry bioactive components INTERNATIONAL JOURNAL OF FOOD SCIENCE & TECHNOLOGY | 2018
a
Antibacterial and antibiofilm activities of nonpolar extracts of Allium stipitatum Regel. against multidrug resistant bacteria BioMed research international | 2018
a
Drug‐like dietary vanilloids induce anticancer activity through proliferation inhibition and regulation of bcl‐related apoptotic proteins Phytotherapy Research | 2018
a
Galangin’s potential as a functional food ingredient Journal of Functional Foods | 2018
a
Carbon nanotubes (CNTs) based advanced dermal therapeutics: current trends and future potential Nanoscale | 2018
a
Transferrin receptors-targeting nanocarriers for efficient targeted delivery and transcytosis of drugs into the brain tumors: a review of recent advancements and emerging trends Drug delivery and translational research | 2018
a
An update on natural compounds in the remedy of diabetes mellitus: A systematic review Journal of traditional and complementary medicine | 2018
a
Carbon nanotubes in the delivery of anticancer herbal drugs Nanomedicine | 2018
a
An Evaluation of Antimicrobial Activity of Different Extracts of Dillenia suffruticosa Stem Bark. INTERNATIONAL MEDICAL JOURNAL | 2017
a
Thiazolopyridines Improve Adipocyte Function by Inhibiting 11 Beta-HSD1 Oxoreductase Activity Journal of Chemistry | 2017
a
Cinnamomum genus: A review on its biological activities INT J PHARM PHARM SCI | 2017
a
A comprehensive review on polyelectrolyte complexes Drug discovery today | 2017
a
An in silico approach towards the identification of novel inhibitors of the TLR-4 signaling pathway Journal of Biomolecular Structure and Dynamics | 2016
a
Stress degradation studies and development of a validated RP-HPLC method for determination of tiagabine in presence of its degradation products INTERNATIONAL JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES | 2016
a
Acute oral toxicity studies of Swietenia macrophylla seeds in Sprague Dawley rats PHARMACOGNOSY RESEARCH | 2015
a
Basic ionic liquid [bmIm] OH–mediated Gewald reaction as green protocol for the synthesis of 2-aminothiophenes Synthetic Communications | 2015
a
Chemistry content in the pharmacy curriculum: relevance to develop pharmacists fit-to-work in diverse pharmacy profession sectors IND J PHARM EDU RES | 2015
a
Molecular docking studies and comparative binding mode analysis of FDA approved HIV protease inhibitors ASIAN J. CHEM | 2014
a
In silico binding mode analysis (molecular docking studies) and absorption, distribution, metabolism and excretion prediction of some novel inhibitors of Aurora Kinase A in clinical trials Asian Journal of Chemistry | 2014
a
A stability-indicating RP-HPLC method for simultaneous determination of simvastatin and niacin in a combined dosage form Int J Pharm Sci | 2014
a
In vitro antibacterial effects of Cinnamomum extracts on common bacteria found in wound infections with emphasis on methicillin-resistant Staphylococcus aureus Journal of ethnopharmacology | 2014
a
The clinical effects of Synsepalum dulcificum: a review Journal of medicinal food | 2014
a
Chalcones with electron-withdrawing and electron-donating substituents: anticancer activity against TRAIL resistant cancer cells, structure–activity relationship analysis and regulation of apoptotic proteins European Journal of Medicinal Chemistry | 2014
a
2-Methoxy-4-(prop-2-en-1-yl) phenyl 4-methoxybenzoate ACTA CRYSTALLOGRAPHICA SECTION E: STRUCTURE REPORTS ONLINE | 2013
a
Should a Toll-like receptor 4 (TLR-4) agonist or antagonist be designed to treat cancer? TLR-4: its expression and effects in the ten most common cancers OncoTargets and therapy | 2013
a
6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ) Cancer letters | 2013
a
Antiinflammatory evaluation and docking studies of some new thienopyrimidines Asian Journal of Chemistry | 2013
a
Antibacterial and antifungal testing of the different extract of Dillenia obovata (Blume) Hoogl WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES | 2013
a
Pharmacophore-Based 3D-QSAR Studies of Aromatase Inhibitors. Asian Journal of Chemistry | 2013
a
Evaluation of four extracts from Dillenia ovata stem bark and leaves for antibacterial and antifungal activity INTERNATIONAL JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES | 2013
a
2-Methoxy-4-(prop-2-en-1-yl) phenyl 2, 4-dichlorobenzoate ACTA CRYSTALLOGRAPHICA SECTION E: STRUCTURE REPORTS ONLINE | 2013
a
6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ). N/A | 2013
a
2-Methoxy-4-(prop-2-en-1-yl) phenyl benzoate ACTA CRYSTALLOGRAPHICA SECTION E: STRUCTURE REPORTS ONLINE | 2013
a
Effects of Hopea Extracts on Human Colorectal Cancer Cell Proliferation via Induction of Apoptosis N/A | 2012
a
Inhibition of Human Estrogen Dependent Breast Carcinoma Proliferation by Hopea odarata and Hopea ponga N/A | 2012
a
Synthesis and Evaluation of Benzalacetophenone Derivatives in Inhibiting Human Colorectal Cancer Proliferation through Peroxisome Proliferator-activated Receptor Gamma (PPARg) N/A | 2012
a
Resveratrol: Inhibition of TLR-4 Dimerisation and Its Molecular Interactions with TLR-4. N/A | 2012
a
Betulinic Acid Inhibits Toll-like Receptor 4 (TLR $) Dimerisation and Its Molecular Interactions. N/A | 2012
a
Antiproliferafive Activity of Hopea ponga and Hopea odorata Leaves and Stem Bark on Leukemia Cancer Cell Lines (CEM-SS) N/A | 2012
a
The Cytotoxic Activities of Hopea odorata and Hopea ponga Extracts on Human Ovarian Cancer Cells N/A | 2012
a
Antiproliferative Property of Hopea odorata and Hopea ponga Extracts on Human Cervical Cancer Cells N/A | 2012
a
Synthesis of Chalcones and Evaluation of Their Antiproliferative Activity on Human Colorectal Cancer (HT-29) Cell Lines N/A | 2012
a
Identification of Toll-like Receptor 4 Signaling Inhibitors as Potential Compounds Towards Treatment of Skin Immune Disorders. N/A | 2012
a
Screening of Ximenia americana L. for it’s anti-iflammatory activity J. RES. EDUC. INDIAN MED | 2012
a
Effects of Etlingera elatior extracts on lead acetate-induced testicular damage: A morphological and biochemical study EXPERIMENTAL AND THERAPEUTICS MEDICINE | 2012
a
In Vitro Cytotoxic Effects of Hopea odorata and Hopea ponga on Estrogen Independent Breast Cancer N/A | 2012
a
Acute toxicity and hepatoprotective effect of methanolic extract of Tephrosia calophylla RES J MED PLANT | 2011
a
Evaluation of adaptogenic activity of Prunella vulgaris INT J PHARM SCI RES | 2011
a
Flammability behavior of fiber–fiber hybrid fabrics and composites Journal of Applied Polymer Science | 2011
a
Resazurin assay for determination of antimicrobial activity in Dillenia ovata Leveraging on Microbial Diversity for a Sustainable Future: Proceedings of the International Congress of the Malaysian Society for Microbiology 2011 | 2011
a
Preliminary screening of Syzygium cumini and Achyranthes aspera for their anthelmintic activity RESEARCH JOURNAL OF PHARMACOGNOSY AND PHYTOCHEMISTRY | 2010
a
Antiproliferative activity of Bauhinia blakeana on estrogen receptor negative human breast cancer (MDA-MB-231) cells PLANTA MEDICA | 2010
a
Comparative antioxidant and anti-inflammatory effects of [6]-gingerol,[8]-gingerol,[10]-gingerol and [6]-shogaol. N/A | 2010
a
Evaluation of hepatoprotective activity of Prunella vulgaris by carbontetrachloride induced hepatotoxicity parameters | 2010
a
Evaluation of Antiulcerogenic Activity of Tephrosia calophylla Roots on Aspirin Plus Pyloric Ligation-induced Ulcers in Experimental Rats Planta Medica | 2010
a
Antiproliferative activity and induction of apoptosis in estrogen receptor-positive and negative human breast carcinoma cell lines by Gmelina asiatica roots PHARMACOGNOSY RESEARCH | 2010
a
Protective effects of Etlingera elatior extract on lead acetate-induced changes in oxidative biomarkers in bone marrow of rats Food and Chemical Toxicology | 2010
a
Antimicrobial activity of Bauhinia tomentosa and Bauhinia vahlii roots Pharmacognosy magazine | 2010
a
Protective effect of Etlingera elatior (torch ginger) extract on lead acetate-induced hepatotoxicity in rats The Journal of toxicological sciences | 2010
a
Comparative antioxidant and anti-inflammatory effects of [6]-gingerol,[8]-gingerol,[10]-gingerol and [6]-shogaol Journal of ethnopharmacology | 2010
a
Phytochemical Screening and antimicrobial activity of alcohol extracts from leaf and bark of Ficus mollis JOURNAL OF PHARMACY AND CHEMISTRY | 2009
a
Solid state fermentation for the production of L-asparaginase from by aspergillus species RESEARCH JOURNAL OF PHARMACOGNOSY AND PHYTOCHEMISTRY | 2009
a
Mutation induced enhanced bio synthesis of anti tumor L-Asparagine JOURNAL OF PHARMACY AND CHEMISTRY | 2009
a
Nasopharyngeal Carcinoma cell proliferation and apoptosis induced by the standardised ethanolic extracts of Mucuna bracteata Malaysian Journal of Chemistry | 2009
a
Growth inhibition and induction of apoptosis in estrogen receptor positive and negative human breast carcinoma cells by Tephrosia calophylla roots JOURNAL OF PHARMACY AND CHEMISTRY | 2009
a
Phytochemical screening and analgesic activity of methanolic extract of Ximenia americana JOURNAL OF PHARMACY AND CHEMISTRY | 2009
a
Antiproliferative and apoptotic studies of the standardised extracts of Etlingera elatior on human colorectal carcinoma cells Malaysian Journal of Chemistry | 2009
a
Solid-state fermentation for the production of l-asparaginase by Aspergillus Sp RESEARCH JOURNAL OF PHARMACOGNOSY AND PHYTOCHEMISTRY | 2009
a
Growth inhibition and induction of apoptosis in estrogen receptor-positive and negative human breast carcinoma cells by Adenocalymma alliaceum flowers Current Trends in Biotechnology and Pharmacy | 2009
a
Optimization of process parameters for the production of L-asparaginase from an isolated fungus RESEARCH JOURNAL OF PHARMACONGNOSY AND PHYTOCHEMISTRY | 2009
a
Screening of anti tumour L-asparaginase positive fungal cultures from soil JOURNAL OF PHARMACY AND CHEMISTRY | 2008
a
Antimicrobial activity of Caesalpinia pulcherrima, Euphorbia hirta and Asystasia gangeticum Fitoterapia | 2006
a
Evaluation of antimicrobial activity of Cleome viscosa and Gmelina asiatica Fitoterapia | 2006
a
Antimicrobial activity of bark of Alangium salvifoloium Linn. F. Indian Journal of Microbiology | 2002

Show More


Other Publications

a
Tetrahydrothiazolo [5, 4-c] pyridines as a new class of antiobesity compounds BRITISH JOURNAL OF PHARMACOLOGY | 01 Jan 2020
a
Development of new bicyclic analogue of sulforaphane as potent nuclear factor erythroid 2-related factor inducer BRITISH JOURNAL OF PHARMACOLOGY | 01 Jan 2020
a
Synthesis of 3-(p-aminophenyl0-5-furyl-1,2,4-triazole and evaluation of its potential for the treatment of gram-negative bacterial sepsis International Conference in Organic Synthesis | 21 Aug 2016
a
Design and Discovery of Novel 11 -hydroxysteroid dehydrogenase type-1 inhibitor International Conference in Organic Synthesis | 21 Aug 2016
a
Exploration of alkylidenemalononitrile enamines towards the synthesis of 4-N,N-dialkylamino-2-chloro/amino International Conference in Organic Synthesis | 21 Aug 2016
a
Synthesis of novel N-vanillylcycloalk-2-ene-1-carboxamide derivatives International Conference in Organic Synthesis | 21 Aug 2016
a
Synthesis of novel drug-like compounds against multi-drug resistant gram negative bacteria targeting CTX-M class A beta lactamase International Conference in Organic Synthesis | 21 Aug 2016
a
Synthesis of 2-(p-aminophenyl)-5-(1,2,4-triazo-N-methyl)-1,2,4-triazole and evaluation its activity against multi-drug resistant bacteria International Conference in Organic Synthesis | 21 Aug 2016
a
A novel method for synthesis of new vanilloids and in vitro evaluation of their anti-inflammatory activity International Conference in Organic Synthesis | 21 Aug 2016
a
Extended Spectrum Antibiotics Against Multidrug Resistant Bacteria Joint Malaysia UK Symposium in Natural Product Chemistry and Drug Discovery | 13 Dec 2014
a
Discovery of Novel Drug-like compounds for controlling amplified inflammatory responses mediating through Toll-like Receptor/Myeloid differentiation protein2 hyper activation 6th International Conference on Drug Discovery and Therapy | 01 Oct 2014
a
Antioxidant and free radical scavenging activity of resveratrol derivatives 1st Joint ACS AGFD ACS ICSCT symposium on agriculture and food chemistry | 04 Jul 2014
a
Antibacterial compounds from Ficus grossularioides active against Mycobacterium marinum 1st Joint ACS AGFD ACS ICSCT symposium on agriculture and food chemistry | 04 Jul 2014
a
NF-kappa B inhibitors from Ficus pumila 1st Joint ACS AGFD ACS ICSCT symposium on agriculture and food chemistry | 01 Jul 2014
a
Discovery of naturally occurring toll-like receptor-4 signalling inhibitors: Their anticancer effects and mechanisms of action EUROPEAN JOURNAL OF CANCER | 01 Jan 2013

Show More


Books

a
Academic Press (2024). Silver nanoparticles in wound therapy and tissue regeneration

Patents

a
Metal-incorporated hyperbranched polyester-polyol | 07 Oct 2017

Medias

a
COMPUTER AIDED DRUG DESIGN IN PHARMA R&D Pharma Focus Asia | 31 Aug 2019


Supervisions
a
Mak Kit Kay | Doctorate | 03 Jan 2019 - 21 Apr 2023 Thesis: Integration of Artificial intelligence (AI) and Computer Aided Drug Discovery (CADD) techniques for the development of novel drug-like Keap1-Nrf2 inhibitors/direct Nrf2 activator
a
Mak Kit Kay | Master (Research) | 10 Jul 2014 - 31 Dec 2016 Thesis: SYNTHESIS OF 4,5,6,7-TETRAHYDROBENZO[b]THIOPHENES AS NOVEL ANTI-INFLAMMATORY AGENTS
a
Low Jun Sheng | Master (Research) | 01 Jan 2019 - 31 Mar 2022 Thesis: Molecular mechanisms involved in wound healing properties of Melastoma malabathricum (L.) using an in vitro approach
a
Pang Jia Chern | Master (Research) | 01 Sep 2019 - 31 May 2023 Thesis: Identification of pharmacophoric features for potent and selective inhibition of 5-Lipoxygenase (5-LO): Synthesis of novel chemotype hybrids and their molecular mechanisms in atherosclerosis
a
SHUAIB FARIDAH OLUBUNMI | Master (Mixed Mode) | 01 Jan 2015 - 30 Nov 2015 Thesis: DESIGN, SYNTHESIS AND EVALUATION OF SOME NEW THIENO[2,3-d]PYRIMIDINE-4-ONE DERIVATIVES AS POSSIBLE CYCLOOXYGENASE-2 (COX-2) INHIBITOR
a
CHUA BING WEI | Master (Research) | 01 Jan 2013 - 01 Jul 2017 Thesis: COBALT-CONJUGATED POLY(GLYCEROL ADIPATE): SYNTHESIS, CHARACTERISATION AND EVALUATION OF THEIR POTENTIAL AS ANTIMICROBIAL POLYURETHANE COATING MATERIALS
a
MUNA ALI OTHMAN SALEM | Master (Mixed Mode) | 01 Jan 2017 - 31 Dec 2017 Thesis: SYNTHESIS AND BIOLOGICAL EVALUATION OF N-VANILLYLCYCLOALK-1-ENE-1-CARBOXAMIDES FOR THEIR ANTI-INFLAMMATORY ACTIVITY IN BV2 AND RAW 264.7 CELL LINES
a
TAN YEE HON | Master (Mixed Mode) | 01 Jan 2014 - 01 Jan 2015 Thesis: DETECTION AND QUANTIFICATION OF SILDENAFIL AND TADALAFIL AS ADULTERANTS IN COMMERCIAL HERBAL SUPPLEMENTS USING HPLC
a
RAJAKUMARI A/P RAJASINGAM | Master (Mixed Mode) | 01 May 2014 - 01 May 2015 Thesis: DEVELOPMENT OF A VALIDATED RP-HPLC METHOD FOR THE DETERMINATION OF TIAGABINE AND ITS DEGRADED FORMS IN BULK AND PHARMACEUTICAL DOSAGE FORMS
a
PUVANESWARI MARAPPAN | Master (Research) | 01 Jan 2016 - 31 May 2018 Thesis: SYNTHESIS OF NOVEL TETRAHYDROTHIAZOLO(5,4-c)PYRIDINES AND IN- VITRO EVALUATION OF THEIR ANTI-INFLAMMATORY ACTIVITY
a
KULASEKAR KULASINGAM | Master (Mixed Mode) | 09 Mar 2013 - 03 Mar 2014 Thesis: ANTIMICROBIAL STUDIES ON ALTERNANTHERA SESSILIS Red LEAVES
a
YOUSEF ABDULSAMIE AWEEN | Master (Mixed Mode) | 01 Jun 2017 - 01 Jun 2018 Thesis: INVESTIGATION OF ANTI-INFLAMMATORY AND ANTIOXIDANT PROPERTIES OF ANDROGRAPHOLIDE IN A MOUSE MODEL OF ATHEROSCLEROSIS
a
Mai Chun Wai | Doctorate | 01 Jan 2012 - 19 Dec 2014 Thesis: DISCOVERY, STRUCTURE-ACTIVITY RELATIONSHIP STUDIES OF BENZYLIDENEACETOPHENONES AND METHOXYPHENOLS TARGETING TOLL-LIKE RECEPTOR-4 (TLR-4) AND THEIR MOLECULAR MECHANISMS IN CANCER
a
AYUBA SUNDAY BURU | Doctorate | 01 Jan 2012 - 13 Mar 2014 Thesis: CINNAMOMUM, ITS ANTIBACTERIAL EFFECTS AND CINNAMOMUM IMPRESSICOSTATUM, IDENTIFICATION OF BIOACTIVE CONSTITUENTS AND POSSIBLE MECHANISMS OF ACTION AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS
a
YAMEN ALKHATEEB | Master (Mixed Mode) | 01 Jan 2017 - 17 Nov 2017 Thesis: IN VIVO PHARMACOKINETICS AND ORAL BIOAVAILABILITY OF ANDROGRAPHOLIDE IN SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEM FORMULATION USING UPLC-MS/MS
a
DAFER HASSAN MOHAMED ALHAJ | Master (Research) | 05 Jan 2017 - 25 Jan 2018 Thesis: THE INFLUENCE OF ELECTRON DONATING SUBSTITUENTS AT META-POSITIONS OF AROMATIC RINGS IN BENZYLIDENEACETOPHENONE ON THEIR IN VITRO ANTI-INFLAMMATORY ACTIVITY
a
OSAMA H O ALMAJDOUB | Master (Mixed Mode) | 22 Jul 2016 - 20 Jul 2017 Thesis: The Influence of Halogens at Meta-positions of Aromatic Rings In Chalcones on Their In Vitro Anti-inflammatory Activity
a
TAI ZHI SAM | Master (Mixed Mode) | 16 Feb 2017 - 28 Jul 2018 Thesis: EFFECT OF 14-DEOXY-11,12-DIDEHYDROANDROGRAPHOLIDE IN POLOXAMER-407 INDUCED ATHEROSCLEROSIS IN C57BL/6J MOUSE
a
VALSALA RAMACHANDRAN | Doctorate | 11 Jun 2010 - 12 Jun 2014 Thesis: ANTITHOMBOTIC ACTION OF MORINDA CITRIFOLIA FRUIT EXTRACT: MECHANISM OF ACTION AND CHEMICAL CHARACTERIZATION.
a
BU HUEY ENN | Master (Mixed Mode) | 01 Dec 2021 - 30 Sep 2022 Thesis: SYNTHESIS OF NEW EUGENOL DERIVATIVES AND EVALUATION OF THEIR ANTI-INFLAMMATORY ACTIVITY
a
UNG SER MING | Master (Mixed Mode) | 31 Dec 2021 - 30 Oct 2022 Thesis: SYNTHESIS OF NEW EUGENOL DERIVATIVES AND THE EVALUATION OF THEIR ANTIBACTERIAL ACTIVITY

Show More