a
More than just a KRAS inhibitor: DCAI abrogates the self-renewal of pancreatic cancer stem cells in vitro
ONCOLOGIE | 2023
a
Interplay Between Autophagy And Apoptosis In A Pancreatic Cancer Cell Line Treated With SRJ23, Gemcitabine Or Combination Of Both Agents.
MALAYSIAN JOURNAL OF MEDICINE & HEALTH SCIENCES | 2022
a
Pharmacological Modulation of Apoptosis and Autophagy in the Treatment of Pancreatic Cancer
MINI REVIEWS IN MEDICINAL CHEMISTRY | 2022
a
The impact of cycleanine in cancer research: a computational study
JOURNAL OF MOLECULAR MODELING | 2022
a
Pancreatic cancer treatment with targeted therapies: are we there yet?
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | 2022
a
Melanoma metastasis: What role does melanin play?
ONCOLOGY REPORTS | 2022
a
Microarray-based identification of differentially expressed genes associated with andrographolide derivatives-induced resistance in colon and prostate cancer cell lines
TOXICOLOGY AND APPLIED PHARMACOLOGY | 2021
a
Toxicological and pharmacokinetic analysis at therapeutic dose of SRS27, an investigational anti-asthma agent
NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY | 2021
a
AK‐RAS Inhibitor Abrogates Self‐Renewal of Pancreatic Cancer Stem Cells via K‐RAS–NF‐κB–SOX2 Axis
THE FASEB JOURNAL | 2020
a
In silico and saturation transfer difference NMR approaches to unravel the binding mode of an andrographolide derivative to K-Ras oncoprotein
FUTURE MEDICINAL CHEMISTRY | 2020
a
In silico and saturation transfer difference NMR approaches to unravel the binding mode of an andrographolide derivative to K-Ras oncoprotein (vol 12, pg 1611, 2020)
FUTURE MEDICINAL CHEMISTRY | 2020
a
Advances and challenges in developing andrographolide and its analogues as cancer therapeutic agents
DRUG DISCOVERY TODAY | 2019
a
Edible foxtail millet flour stabilises and retain the in vitro activity of blueberry bioactive components.
N/A | 2018
a
Edible foxtail millet flour stabilises and retain the in vitro activity of blueberry bioactive components
INTERNATIONAL JOURNAL OF FOOD SCIENCE & TECHNOLOGY | 2018
a
SRJ09, a promising anticancer drug lead: Elucidation of mechanisms of antiproliferative and apoptogenic effects and assessment of in vivo antitumor efficacy
PHARMACOLOGICAL RESEARCH | 2016
a
A semisynthetic diterpenoid lactone inhibits NF-κB signalling to ameliorate inflammation and airway hyperresponsiveness in a mouse asthma model
TOXICOLOGY AND APPLIED PHARMACOLOGY | 2016
a
Acute oral toxicity studies of Swietenia macrophylla seeds in Sprague Dawley rats
PHARMACOGNOSY RESEARCH | 2015
a
Targeting the undruggable KRAS: In vitro anticancer property of andrographolide and its semisynthetic analogues in pancreatic adenocarcinoma cell lines harbouring oncogenic mutant K-ras
>**'**,-- | 2015
a
靶向 K-ras 的半合成穿心莲内酯衍生物: 发现潜在抗癌药物先导物的有效方法 (英文)
>**'**,-- | 2015
a
SRS06, a new semisynthetic andrographolide derivative with improved anticancer potency and selectivity, inhibits nuclear factor-κB nuclear binding in the A549 non-small cell lung cancer cell line
PHARMACOLOGY | 2015
a
Stress degradation studies and development of a validated RP-HPLC method for determination of tiagabine in presence of its degradation products
INTERNATIONAL JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES | 2015
a
SRS27, a semisynthetic diterpenoid lactone, inhibits airway inflammation and hyper-responsiveness via NF-κB pathway in an allergic mouse asthma model
>**'**,-- | 2015
a
Salt stress-induced protein pattern associated with photosynthetic parameters and andrographolide content in Andrographis paniculata Nees
BIOSCIENCE, BIOTECHNOLOGY, AND BIOCHEMISTRY | 2015
a
In vitro 3D evaluation of penetrability of SRJ09, a semisynthetic anticancer agent (1048.4)
THE FASEB JOURNAL | 2014
a
SRJ09, a semisynthetic anticancer agent, targets Ras-MAPK signaling pathway: assessment in breast and colon cancer cell lines
CANCER RESEARCH | 2014
a
In vitro 3D colon tumor penetrability of SRJ09, a new anti-cancer andrographolide analog
INVESTIGATIONAL NEW DRUGS | 2014
a
A stability-indicating RP-HPLC method for simultaneous determination of simvastatin and niacin in a combined dosage form
INTERNATIONAL JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES | 2014
a
NCI in vitro and in silico anticancer screen, cell cycle pertubation and apoptosis-inducing potential of new acylated, benzylidene and isopropylidene derivatives of andrographolide
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY | 2014
a
SRJ23, a new semisynthetic andrographolide derivative: in vitro growth inhibition and mechanisms of cell cycle arrest and apoptosis in prostate cancer cells
CELL BIOLOGY AND TOXICOLOGY | 2014
a
A classical genetic solution to enhance the biosynthesis of anticancer phytochemicals in Andrographis paniculata Nees
PLOS ONE | 2014
a
Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES | 2013
a
Analysis of the anticancer phytochemicals in Andrographis paniculata Nees. under salinity stress
BIOMED RESEARCH INTERNATIONAL | 2013
a
Prevalence of macrolide resistance and in vitro activities of six antimicrobial agents against clinical isolates of Streptococcus pneumoniae from a multi-center surveillance in Malaysia
MED J MALAYSIA | 2013
a
Research Article Analysis of the Anticancer Phytochemicals in Andrographis paniculata Nees. under Salinity Stress
N/A | 2013
a
Abstract C147: Mechanism of resistance to a semisynthetic anticancer andrographolide derivative: Possible involvement of Ras-MAPK signaling pathway.
MOLECULAR CANCER THERAPEUTICS | 2013
a
SRJ23, a potent inducer of cell cycle arrest and apoptosis in prostate cancer cells
THE FASEB JOURNAL | 2012
a
Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY | 2012
a
Andrographolide induces cell cycle arrest and apoptosis in PC-3 prostate cancer cells
AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY | 2011
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Andrographolide as a template in the synthesis of new anticancer agents with potentially novel molecular targets
THE FASEB JOURNAL | 2010
a
132 POSTER SRJ09, a lead compound in anticancer drug design: in vitro, in vivo and mechanistic studies
EUROPEAN JOURNAL OF CANCER SUPPLEMENTS | 2008
a
14-Deoxy-11, 12-didehydro-3, 19-isopropylideneandrographolide
ACTA CRYSTALLOGRAPHICA SECTION E: STRUCTURE REPORTS ONLINE | 2006
a
3, 19-(2-Bromobenzylidene) andrographolide
ACTA CRYSTALLOGRAPHICA SECTION E: STRUCTURE REPORTS ONLINE | 2006
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3, 19-(2, 6-Dimethoxybenzylidene) andrographolide
ACTA CRYSTALLOGRAPHICA SECTION E: STRUCTURE REPORTS ONLINE | 2006
a
Phytochemicals from Phyllanthus niruri Linn. and their pharmacological properties: a review
JOURNAL OF PHARMACY AND PHARMACOLOGY | 2006
a
SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF GATIFLOXACIN
ORIENTAL JOURNAL OF CHEMISTRY | 2003
a
Virtual Educational Field Trips: Making meaningful engagement possible for remote learning environments
Variety in Chemistry Education and the Physics Higher Education Conference (ViCEPhEC2020) | 17 Aug 2020
a
Assessment of Competence in Medicine and Health Professions
OTTAWA 2020 | 28 Feb 2020
a
Synthesis and biological evaluation of new benzylidene derivatives of 12,13-dihydroandrographolide analogues as neuroprotective agents
47th IUPAC World Chemistry Congress (IUPAC 2019) | 05 Jul 2019
a
Leveraging the Versatility of Cloud-based Apps to Foster 4C's of Learning: A Case of Facilitating Hands-on Workshop on Structure Determination
47th IUPAC World Chemistry Congress (IUPAC 2019) | 05 Jul 2019
a
Leveraging reliability and versatility of cloud-based apps to foster critical thinking and collaborative skills in synchronous learning environments
10th Asian Medical Education Association Symposium (AMEA 2019) | 12 Apr 2019
a
Quantitative analysis of andrographolide, a biomarker of Andrographis paniculata, using qNMR spectroscopy
International Conference on Drug Discovery and Translational Medicine 2018 (ICDDTM'18) | 03 Dec 2018
a
Determination of the Binding Mode of An Andrographolide Derivative to K-Ras Oncoprotein via Molecular Modelling and STD-NMR
Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 (The 18th World Congress of Basic and Clinical Pharmacology) | 01 Jan 2018
a
DRUGGING THE ELUSIVE RAS ONCOPROTEIN WITH SEMISYNTHETIC ANDROGRAPHOLIDE DERIVATIVES
Proceedings for Annual Meeting of The Japanese Pharmacological Society WCP2018 (The 18th World Congress of Basic and Clinical Pharmacology) | 01 Jan 2018
a
Protection and Deprotection of 1,2- and 1,3-Diols as Acetonides using PVP/Iodine, a mild, efficient and reusable catalyst
International Conference | 21 Aug 2016
a
A stability-indicating RP-HPLC method for simultaneous determination of simvastatin and niacin in a combined dosage form
Drug Analysis 2014 | 22 Jun 2014
a
SRJ23, A NEW INVESTIGATIONAL ANTI‐PROSTATE CANCER AGENT
FASEB Journal | 01 Jan 2010
a
H-bonds in andrographolide and related molecules: Neutron diffraction, database and modeling studies
Acta Crystallographica A - Foundation and Advances | 01 Jan 2008
a
Ogochukwu Ngozi | Doctorate | 03 Nov 2017 - 30 Dec 2022
Thesis: An Ethnobotanical Study of Anticancer Plants and Bioactivity-guided isolation of Cytotoxic agents from Synchlisia scabrida
a
Quah Shun Ying | Doctorate | 15 Nov 2016 - 10 Jul 2021
Thesis: SRJ23 and its Derivatives as New Anticancer Agents Targeting Ras-Map Kinase and NF-Kb Pathways: In Silico and In Vivo approaches
a
Teh Yuan Han | Doctorate | 30 Nov 2014 - 12 Jun 2020
Thesis: Blocking Signalling through CD44 in Pancreatic Cancer Stem Cells. PhD Co- supervisor 2020
a
Ramesh Ranggasamy | Doctorate | 15 Nov 2018
Thesis: Immunomodulatory Activity of Standardised Aqueous Ethanolic Extract of Moringa oleifera Lam. Leaves In vivo
a
Dineshwar Sugumaran | Doctorate | 15 Sep 2022
Thesis: Molecular insights into the action of new andrographolide derivatives as anti-psoriatic agents PhD Co- supervisor In progress
a
Nityaa Selvarajoo | Master (Research) | 15 Feb 2018 - 15 Jun 2022
Thesis: Interplay between autophagy and apoptosis in gemcitabine resistant pancreatic cancer
a
Michelle Siying | Master (Research) | 15 Nov 2013 - 15 Jun 2019
Thesis: SRJ23 and its Derivatives as New Anticancer Agents Targeting Ras-Oncoprotein: In Vitro and Protein Crystallography Approaches MSc Co- supervisor 2019
a
Sopna Devi Ravindran | Master (Research) | 15 Feb 2018 - 15 Jun 2022
Thesis: Deciphering the interplay between autophagy and apoptosis in gemcitabine resistant pancreatic cancer MSc Co- supervisor 2022
a
Zhi Sam Tai | Master (Mixed Mode) | 15 Sep 2017 - 15 Mar 2018
Thesis: Efficacy and molecular mechanism studies of 14-deoxy-11,12-didehydroandrographolide in regression of poloxamer 407-induced atherosclerosis in mouse model
a
Yamen Al Khateeb | Master (Mixed Mode) | 15 Sep 2016 - 15 Mar 2017
Thesis: In-Vivo Pharmacokinetics and Oral Bioavailability of Andrographolide in SMEDDS, Formulation using HPLC
a
Tan Khai Shin | Master (Mixed Mode) | 15 Dec 2015 - 15 Dec 2016
Thesis: Drug-like labdane diterpenes as neuroprotective agents: Synthesis and evaluation of NF-Kb inhibitory property and in vitro metabolic stability
a
Rajakumari Rajasingam | Master (Mixed Mode) | 15 Dec 2014 - 15 Sep 2015
Thesis: Stress Degradation Studies on Tiagabine and Development of a Validated RP-HPLC Method for its Determination in Bulk and Dosage Forms
a
Tan Yee Hon | Master (Mixed Mode) | 15 Sep 2014 - 15 Mar 2015
Thesis: Identification and quantification of various synthetic adulterants in registered herbal supplements in Malaysia: a preliminary study using LCMS
a
Jeyashantini Nalaiya | Master (Mixed Mode) | 15 Sep 2013 - 15 Mar 2014
Thesis: Development and validation of a stability-indicating RP-HPLC method for simultaneous determination of simvastatin and niacin in a combined product
a
Kulasekar Kulasingam | Master (Mixed Mode) | 15 Sep 2013 - 15 Mar 2014
Thesis: Phytochemical and Antimicrobial Studies on Alternanthera sessilis Linn Leaves
a
Yew Siu Hui | Undergraduate | 15 Apr 2022 - 15 Jun 2022
Thesis: Composition and variability of selected medicinal essential oils in correlation with their antioxidant properties in vitro: A chemometrics approach using ATR-FTIR and NMR spectroscopies (Apr- Jun 2022)
a
Lee Zin Chee | Undergraduate | 15 Apr 2022 - 15 Jun 2022
Thesis: Composition and variability of selected medicinal essential oils in correlation with their antioxidant properties in vitro: A chemometrics approach using ATR-FTIR and NMR spectroscopies (Apr- Jun 2022)
a
Reginia Ho Qin Qing | Undergraduate | 15 Apr 2022 - 15 Jun 2022
Thesis: Composition and variability of selected medicinal essential oils in correlation with their antioxidant properties in vitro: A chemometrics approach using ATR-FTIR and NMR spectroscopies (Apr- Jun 2022)
a
Kiranjeet Kaur Bajwa | Undergraduate | 15 Apr 2021 - 15 Jun 2021
Thesis: Evaluation of the potential of chemometrics-assisted FTIR spectroscopy for authentication analysis of selected commercial medicinal essential oils
a
Tuang Ling Kai | Undergraduate | 15 Apr 2021 - 15 Jun 2021
Thesis: Evaluation of the potential of chemometrics-assisted FTIR spectroscopy for authentication analysis of selected commercial medicinal essential oils
a
Dorea Soong Shi Hui | Undergraduate | 15 Apr 2021 - 15 Jun 2021
Thesis: Evaluation of the potential of chemometrics-assisted FTIR spectroscopy for authentication analysis of selected commercial medicinal essential oils
a
Shawnice Lim Xiao Shian | Undergraduate | 15 Apr 2021 - 15 Jun 2021
Thesis: Evaluation of the potential of chemometrics-assisted FTIR spectroscopy for authentication analysis of selected commercial medicinal essential oils
a
Raden Seri Shazrina | Undergraduate | 15 Aug 2022 - 15 Oct 2022
Thesis: Phytochemical profiling and evaluation of antioxidant and antibacterial potential of polyphenolic-rich fractions of selected medicinal plants of Malaysia
a
Kiberly Tan Hwee | Undergraduate | 15 Aug 2022 - 15 Oct 2022
Thesis: Phytochemical profiling and evaluation of antioxidant and antibacterial potential of polyphenolic-rich fractions of selected medicinal plants of Malaysia
a
Lee Jie Ying | Undergraduate | 15 Aug 2022 - 15 Oct 2022
Thesis: Phytochemical profiling and evaluation of antioxidant and antibacterial potential of polyphenolic-rich fractions of selected medicinal plants of Malaysia
a
Tong Tze Hau | Undergraduate | 15 Jul 2014 - 15 Dec 2014
Thesis: Neuroprotective Activity of Andrographolide Analogues in Neuronal Cell lines
a
Albert Tan Bean Yao | Undergraduate | 15 Jul 2014 - 15 Dec 2014
Thesis: Neuroprotective Activity of Andrographolide Analogues in Neuronal Cell lines
a
Augustine Foong Hua Yi | Undergraduate | 15 Jul 2014 - 15 Dec 2014
Thesis: Neuroprotective Activity of Andrographolide Analogues in Neuronal Cell lines
a
Yogeshini Batumalai | Undergraduate | 15 Aug 2014 - 15 Dec 2014
Thesis: Neuroprotective Activity of Andrographolide Analogues in Neuronal Cell lines
a
Hema A/P Balakrishnan | Undergraduate | 15 Aug 2014 - 15 Dec 2014
Thesis: Neuroprotective Activity of Andrographolide Analogues in Neuronal Cell lines
a
Chu Vun San | Undergraduate | 15 Jun 2016 - 15 Sep 2016
Thesis: Comparative quantitative analysis of andrographolide, a biomarker of Andrographis paniculata by chromatography, ATR-FTIR and qNMR spectroscopy
a
Kong La Ling | Undergraduate | 15 Jun 2016 - 15 Sep 2016
Thesis: Comparative quantitative analysis of andrographolide, a biomarker of Andrographis paniculata by chromatography, ATR-FTIR and qNMR spectroscopy
a
Phang Sze Ying | Undergraduate | 15 Jun 2016 - 15 Sep 2016
Thesis: Comparative quantitative analysis of andrographolide, a biomarker of Andrographis paniculata by chromatography, ATR-FTIR and qNMR spectroscopy
a
Toh Boon Ling | Undergraduate | 15 Jun 2016 - 15 Sep 2016
Thesis: Comparative quantitative analysis of andrographolide, a biomarker of Andrographis paniculata by chromatography, ATR-FTIR and qNMR spectroscopy
