WONG LAI CHUN



Salutation
Dr

School/Centre
School of Pharmacy

Department
Pharmaceutical Chemistry

Position
Senior Lecturer




Education

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PhD (Chemistry), 2010 Northumbria University
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MRes. Chemical Biology (Chemistry), 2006 Northumbria University
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B.Sc. Chemistry (Hons) (Chemistry), 2005 University Malaya

Memberships

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Royal Society of Chemistry | International | Member Communities Board
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Royal Society of Chemistry | International | Secretary of RSC Malaysia Local Section
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Royal Society of Chemistry | International | Member

Publications

Research Articles

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Comparison of vegetable oils on the uptake of lutein and zeaxanthin by ARPE-19 cells INTERNATIONAL JOURNAL OF OPHTHALMOLOGY | 2023
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Analytical Validation of a Reversed-Phase Ion Pairing HPLC-DAD Method for the Simultaneous Determination of Anthropogenic Pollutants METHODS AND OBJECTS OF CHEMICAL ANALYSIS | 2023
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Coffee consumption revealed sex differences in host endogenous metabolism and gut microbiota in healthy adults JOURNAL OF FOOD BIOCHEMISTRY | 2020
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The synthesis of trifluoromethylated N-nitroaryl-2-amino-1, 3-dichloropropane derivatives and their evaluation as potential anti-cancer agents BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2020
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Development and validation of a script concordance test (SCT) to evaluate ethical reasoning ability among first and fifth year students in a medical school JOURNAL OF ACADEMIC ETHICS | 2019
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Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells CUTANEOUS AND OCULAR TOXICOLOGY | 2018
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Antioxidants and cactus extract enhances the sun protection factor of octocrylene and oxybenzone solution Malaysian Journal of Fundamental and Applied Sciences | 2018
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DEVELOPMENT AND VALIDATION OF A REVERSE PHASE-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY-ULTRAVIOLET METHOD FOR SIMULTANEOUS DETECTION OF CAFFEINE AND PHENOLPHTHALEIN IN WEIGHT REDUCING SUPPLEMENTS MALAYSIAN JOURNAL OF ANALYTICAL SCIENCES | 2017
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Studies relating to the synthesis, enzymatic reduction and cytotoxicity of a series of nitroaromatic prodrugs BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2016
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Convenient Synthesis of Highly Substituted Imidazole Derivatives SYNTHETIC COMMUNICATIONS | 2013
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The Synthesis of Some Novel 1, 2‐Dihydroisoquinoline Derivatives JOURNAL OF HETEROCYCLIC CHEMISTRY | 2013
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The synthesis of 2-nitroaryl-1, 2, 3, 4-tetrahydroisoquinolines, nitro-substituted 5, 6-dihydrobenzimidazo [2, 1-a] isoquinoline N-oxides and related heterocycles as potential bioreducible substrates for the enzymes NAD (P) H: quinone oxidoreductase 1 and E. coli nitroreductase BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2011
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An unexpected ring contraction of two nitroaryl pro-drugs: conversion of N-(nitroaryl)-3-chloropiperidine derivatives into N-(nitroaryl)-2-chloromethylpyrrolidines TETRAHEDRON LETTERS | 2010

Other Publications

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INTEGRATING COLLABORATIVE ONLINE PLATFORM INTO THE FLIPPED CLASSROOM International Medical University Learning Resources Festival 2023 | 06 Nov 2023
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The synthesis of shogaols and investigation of their antibacterial activity 4th Commonwealth Chemistry Posters | 04 Oct 2023
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The Use of Virtual Online Debate in the Classroom to Teach Ethics International Medical University Learning Resources Festival 2022 | 14 Nov 2022
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The 9th International Postgraduate Conference on Pharmaceutical Sciences 2022 (IPoPs 2022) | 23 Jun 2022
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Lutein improves cell viability and reduces Alu RNA accumulation in hydrogen peroxide challenged retinal pigment epithelial cells 7th International Postgraduate Conference on Pharmaceutical Sciences (iPoPS2020) | 28 Feb 2020
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In vitro evaluation of the anticancer properties of the N-((1S,2S)-1,3-dichloro-1-phenylpropan-2-yl)aniline derivative (RB8) 12th Malaysian Pharmaceutical Society Pharmacy Scientific Conference | 13 Nov 2015
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In vitro evaluation of the anticancer properties of the N-((1R,2R-1,3-dichloro-1-phenylpropan-2-Yl)aniline Derivative (RB9) 12th Malaysian Pharmaceutical Society Pharmacy Scientific Conference | 13 Nov 2015
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In vitro evaluation of the anti-cancer properties of the (1S,2S)-1-phenyl-2-(phenylamino)propane-1,3-diol derivative (RB4) 12th Malaysian Pharmaceutical Society Pharmacy Scientific Conference | 13 Nov 2015
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In Vitro Evaluation of the Anti-cancer Properties of the (1R,2R)-1-phenyl-2-(phenylamino)propane-1,3-diol Derivative (RB5) 12th Malaysian Pharmaceutical Society Pharmacy Scientific Conference | 13 Nov 2015
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Development of a script concordance test to assess ethical reasoning ability (SCT-ERA): A preliminary study Association for Medical Education in Europe (AMEE) | 30 Aug 2014


Supervisions
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Lee Yen Mae | Undergraduate | 27 Mar 2023 - 03 Jun 2023 Thesis: Development and validation of a RP-HPLC method to determine caffeine and trigonelline content in commercial coffee samples of Malaysian market.
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Cherlyn Cheng Chen Xi | Undergraduate | 27 Mar 2023 - 03 Jun 2023 Thesis: Development and validation of a RP-HPLC method to determine caffeine and trigonelline content in commercial coffee samples of Malaysian market.
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HASEEB AHMED SAYEED KHADAS | Master (Mixed Mode) | 18 May 2023 Thesis: The synthesis of shogaols and investigation of their antimicrobial activity
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Lee Ke Hui | Master (Mixed Mode) | 01 May 2023 Thesis: Ruthenium complexes for antibacterial and anticancer photodynamic therapy
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Lim Siang Han | Undergraduate | 01 Mar 2024 Thesis: Synthesis and Evaluation of 7-shogaol as Potential Antibacterial Agents Against Multidrug-Resistant Pathogens
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Gan Sin Yee | Undergraduate | 01 Mar 2024 Thesis: Synthesis and Evaluation of 8-Shogaol as Potential Antibacterial Agents Against Multidrug-Resistant Pathogens
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Ong Xin Ying | Undergraduate | 01 Mar 2024 Thesis: Synthesis and Evaluation of 9-Shogaol as Potential Antibacterial Agents Against Multidrug-Resistant Pathogens
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Chew Wan Yi | Undergraduate | 01 Mar 2024 Thesis: Synthesis and Evaluation of 10-Shogaol as Potential Antibacterial Agents Against Multidrug-Resistant Pathogens
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DIPESH PATEL A/L SURESHCHANDRA | Undergraduate | 18 Mar 2024 Thesis: Development and Validation of a Stability-Indicating Reverse Phase-Liquid Chromatography Assay for the Determination of Polymeric Surfactants in Natural Rubber Latex
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Soh Yuin Yin | Undergraduate | 18 Mar 2024 Thesis: Development and Validation of a Stability-Indicating Reverse Phase-Liquid Chromatography Assay for the Determination of Polymeric Surfactants in Natural Rubber Latex
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FONG RUI QI RICHELLE | Undergraduate | 18 Mar 2024 Thesis: Development and Validation of a Stability-Indicating Reverse Phase-Liquid Chromatography Assay for the Determination of Polymeric Surfactants in Natural Rubber Latex
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Lee Ching Yee | Master (Mixed Mode) | 16 Nov 2023 Thesis: Development and Validation of RP-HPLC Dissolution Method for Dapagliflozin and Metformin Hydrochloride in Extended-Release Tablets
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NICHOLAS PEH HIAN TUNG | Master (Research) | 01 Jan 2024 Thesis: Stimuli-responsive In-situ gel nanoemulsion for ophthalmic delivery of lutein and zeaxanthin