MAK KIT KAY



Salutation
Ms

School/Centre
School of Pharmacy

Department
Pharmaceutical Chemistry

Position
Lecturer




Education

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PhD in Medical & Health Sciences (Medicinal Chemistry), 2023 International Medical University
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MSc in Medical & Health Sciences (research) (Medicinal Chemistry), 2018 International Medical University
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BSc (Hons) Pharmaceutical Chemistry (Pharmaceutical Chemistry), 2015 International Medical University

Memberships

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Institute Kimia Malaysia (IKM) | National | Member, ChM
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Royal Society of Biology | International | Member
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American Chemical Society | International | Member
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Royal Society of Chemistry | International | Member

Publications

Research Articles

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Design, Synthesis, Anticancer Evaluation and Molecular Docking Studies of Amide Derivatives of Thienopyrimidine Isoxazoles ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL | 2024
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Synthesis and Characterisation of Flavonoid Mannich Bases and the Evaluation of their Cytotoxic Activity LETTERS IN ORGANIC CHEMISTRY | 2024
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Newly discovered clouting interplay between matrix metalloproteinases structures and novel quaternary Ammonium K21: computational and in-vivo testing BMC ORAL HEALTH | 2024
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Artificial intelligence in drug discovery and development DRUG DISCOVERY AND EVALUATION: SAFETY AND PHARMACOKINETIC ASSAYS | 2023
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In-vitro evaluation of the effectiveness of polyphenols based strawberry extracts for dental bleaching SCIENTIFIC REPORTS | 2023
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Cathepsin-K inhibition enhances anti-cancerous activity within oral squamous cell carcinoma cells: Uncloaking the potency of new K21 formulation EXPERIMENTAL CELL RESEARCH | 2023
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Antimicrobial FiteBac® K21 promotes antimicrobial Potency and wound healing HELIYON | 2023
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Swietenine Alleviates Nonalcoholic Fatty Liver Disease in Diabetic Mice via Lipogenesis Inhibition and Antioxidant Mechanisms ANTIOXIDANTS | 2023
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Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability ANTIOXIDANTS | 2023
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Success stories of AI in drug discovery-where do things stand? EXPERT OPINION ON DRUG DISCOVERY | 2022
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Synthesis and Anti‐Inflammatory Activity of 2‐Amino‐4, 5, 6, 7‐tetrahydrobenzo [b] thiophene‐Derived NRF2 Activators CHEMISTRYOPEN | 2022
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Zingiber officinale var. rubrum: Red ginger’s medicinal uses MOLECULES | 2022
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Synthesis and Incorporation of Quaternary Ammonium Silane Antimicrobial into Self‐Crosslinked Type I Collagen Scaffold: A Hybrid Formulation for 3D Printing DENTAL MATERIALS | 2022
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SIMPLE HPLC METHOD FOR THE QUANTIFICATION OF GINGEROLS (4-, 6-, 8-, AND 10-) AND SHOGAOLS (6-, 8-, AND 10-) IN Zingiber officinale var. rubrum SUPERCRITICAL CARBON DIOXIDE (SC-CO2) EXTRACT Rasayan Journal of Chemistry | 2022
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Anti-Inflammatory Effects of Auranamide and Patriscabratine—Mechanisms and In Silico Studies MOLECULES | 2022
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Quercetin and metformin synergistically reverse endothelial dysfunction in the isolated aorta of streptozotocin-nicotinamide-induced diabetic rats SCIENTIFIC REPORTS | 2022
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Studies on the mechanism of anti-inflammatory action of swietenine, a tetranortriterpenoid isolated from Swietenia macrophylla seeds PHYTOMEDICINE PLUS | 2021
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Synthesis and anticancer evaluation of amide derivatives of imidazo-pyridines MEDICINAL CHEMISTRY RESEARCH | 2021
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Effect of propolis nanoparticles against Enterococcus faecalis biofilm in the root canal MOLECULES | 2021
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Swietenine potentiates the antihyperglycemic and antioxidant activity of Metformin in Streptozotocin induced diabetic rats BIOMEDICINE & PHARMACOTHERAPY | 2021
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Design, synthesis, anticancer evaluation and molecular docking studies of chalcone linked pyrido [4, 3-b] pyrazin-5 (6H)-one derivatives JOURNAL OF MOLECULAR STRUCTURE | 2021
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Microwave assisted synthesis and antimicrobial and antioxidant activities of dimers of 1, 2, 3-triazole-benzofuran bearing alkyl spacer derivatives CHEMICAL DATA COLLECTIONS | 2021
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PLGA nanoparticles loaded with quaternary ammonium silane and riboflavin for potential applications in adhesive dentistry INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES | 2021
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The role of DMPK science in improving pharmaceutical research and development efficiency DRUG DISCOVERY TODAY | 2021
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In vitro methods used for discovering plant derived products as wound healing agents–An update on the cell types and rationale FITOTERAPIA | 2021
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Melastoma malabathricum L.: a review of its traditional uses, phytochemical constituents and bioactivities. N/A | 2021
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Concentration-Dependent Multi-Potentiality of L-Arginine: Antimicrobial Effect, Hydroxyapatite Stability, and MMPs Inhibition MOLECULES | 2021
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Molecular Dynamic Simulation Search for Possible Amphiphilic Drug Discovery for Covid-19 MOLECULES | 2021
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Synthesis of quinozilinium fluoroborate salts from harmine CARBON LETTERS | 2021
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Antibacterial and antibiofilm efficacy of k21-E in root canal disinfection DENTAL MATERIALS | 2021
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A quaternary ammonium silane antimicrobial triggers bacterial membrane and biofilm destruction SCIENTIFIC REPORTS | 2020
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New antimicrobial and collagen crosslinking formulated dentin adhesive with improved bond durability JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS | 2020
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Synthesis and antileishmanial activity of fluorinated rhodacyanine analogues: The ‘fluorine-walk’analysis BIOORGANIC & MEDICINAL CHEMISTRY | 2020
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Synthesis and anticancer evaluation of amide derivativesof imidazo-pyridines MEDICINAL CHEMISTRY RESEARCH | 2020
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Hyperbranched poly (glycerol esteramide): A biocompatible drug carrier from glycerol feedstock and dicarboxylic acid JOURNAL OF APPLIED POLYMER SCIENCE | 2020
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New Alkyl (E)-5-(Methylsulfinyl) Pent-4-Enoates from Raphanus sativus Seeds REVISTA BRASILEIRA DE FARMACOGNOSIA | 2020
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Artificial intelligence in drug development: present status and future prospects DRUG DISCOVERY TODAY | 2019
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A comprehensive review on eugenol's antimicrobial properties and industry applications: A transformation from ethnomedicine to industry PHARMACOGNOSY REVIEWS | 2019
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Construction of a novel quinoxaline as a new class of Nrf2 activator BMC CHEMISTRY | 2019
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Drug Delivery Transl RES | 2018
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Carbon nanotubes in the delivery of anticancer herbal drugs NANOMEDICINE | 2018
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Comparison of Cisplatin Monotherapy and Cisplatin-Containing Combination Therapy in Term of Survival Rate in Recurrent Cervical Cancer ACTA SCIENTIFIC PHARMACEUTICAL SCIENCES | 2018
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Galangin’s potential as a functional food ingredient JOURNAL OF FUNCTIONAL FOODS | 2018
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Edible foxtail millet flour stabilises and retain the in vitro activity of blueberry bioactive components INTERNATIONAL JOURNAL OF FOOD SCIENCE & TECHNOLOGY | 2018
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Carbon nanotubes (CNTs) based advanced dermal therapeutics: current trends and future potential NANOSCALE | 2018
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Transferrin receptors-targeting nanocarriers for efficient targeted delivery and transcytosis of drugs into the brain tumors: a review of recent advancements and emerging trends DRUG DELIVERY AND TRANSLATIONAL RESEARCH | 2018

Other Publications

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Design and development of new bicyclic analogue of sulforaphane to induce nuclear factor erythroid 2-related factor PSJ-FIP Joint Session 2022 Part2: New Generation of Pharmaceutical Scientists in Asia-Pacific Regions | 25 Mar 2022
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Tetrahydrothiazolo [5, 4-c] pyridines as a new class of antiobesity compounds British Journal of Pharmacology | 01 Jan 2020
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Development of new bicyclic analogue of sulforaphane as potent nuclear factor erythroid 2-related factor inducer British Journal of Pharmacology | 01 Jan 2020
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Synthesis of New Eugenol Derivatives and Their Antiproliferative Effect in Liver and Colorectal Cancer Cells. 7th International Postgraduate Conference on Pharmaceutical Sciences | 01 Jan 2020
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Tetrahydrothiazolo[5,4-c]pyridines as Inhibitors of Mycobacterium tuberculosis InhA 7th International Postgraduate Conference on Pharmaceutical Sciences 2020 | 01 Jan 2020
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Benzylidenehydrazinylphenylthiazoles as nuclear factor erythroid 2-related factor (nrf2) inducers 7th International Postgraduate Conference on Pharmaceutical Sciences | 01 Jan 2020
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Tetrahydrobenzothiophene as a new class of NRF2 activator. RSC Medicinal Chemistry Summer Residential School 2019 | 01 Jan 2019
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Antibacterial activity of new eugenol derivatives against multidrug resistant Acinetobacter baumannii Setting our sights on infectious diseases | 01 Jan 2019

Books

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Academic Press (2019). Nanoemulsions as effective carriers for the treatment of lung cancer