Yeannie Yap Hui Yeng



Salutation
Dr

School/Centre
School of Health Sciences

Department
Applied Biomedical Science and Biotechnology

Position
Senior Lecturer


Professional Network


Education

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Doctor of Philosophy (Molecular Medicine), 2015 University of Malaya
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Master of Science (Research), 2011 Universiti Tunku Abdul Rahman
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Bachelor of Science (Honours) (Biomedical Science), 2009 Universiti Tunku Abdul Rahman

Memberships

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Organization for Women in Science for the Developing World | International | Member
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International Society for Infectious Diseases (ISID) | International | Member
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Malaysian Society of Biochemistry and Molecular Biology | National | Committee
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Australia Global Alumni | International | Member

Publications

Research Articles

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Comparative analysis of medicinal attributes between Lignosus cameronensis and its sister species NATURAL PRODUCT RESEARCH | 2024
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Corrigendum to The genome of Lignosus tigris: Uncovering its hidden nutraceutical potential, South African Journal of Botany, Volume 154, March 2023, Pages 108–119 SOUTH AFRICAN JOURNAL OF BOTANY | 2024
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RNA-seq transcriptome and pathway analysis of the medicinal mushroom Lignosus tigris (Polyporaceae) offer insights into its bioactive compounds with anticancer and antioxidant potential JOURNAL OF ETHNOPHARMACOLOGY | 2024
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Water-soluble compounds from Lignosus rhinocerus TM02®(xLr™) modulate ACE2 activity and inhibit its interaction with SARS-CoV-2 Spike-Protein FOOD BIOSCIENCE | 2024
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In vivo anti-tumor activity of Lignosus rhinocerus TM02® using a MCF7-xenograft NCr nude mice model JOURNAL OF ETHNOPHARMACOLOGY | 2023
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The wound healing potential of Lignosus rhinocerus and other ethno-myco wound healing agents MYCOBIOLOGY | 2023
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The genome of Lignosus tigris: Uncovering its hidden nutraceutical potential SOUTH AFRICAN JOURNAL OF BOTANY | 2023
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An assessment of oral cancer knowledge, attitudes, and practices among undergraduate students in Malaysian dental schools BMC ORAL HEALTH | 2023
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Assessment of self-perceived malocclusion and barriers to orthodontic treatment: A cross-sectional study JOURNAL OF ORTHODONTIC SCIENCE | 2023
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Activation function 1 of progesterone receptor is required for progesterone antagonism of oestrogen action in the uterus BMC BIOLOGY | 2022
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About this Journal HONG KONG MED J | 2022
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In silico analysis and characterization of medicinal mushroom cystathionine beta-synthase as an angiotensin converting enzyme (ACE) inhibitory protein COMPUTATIONAL BIOLOGY AND CHEMISTRY | 2022
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Immunomodulatory Effect and an Intervention of TNF Signalling Leading to Apoptotic and Cell Cycle Arrest on ORL-204 Oral Cancer Cells by Tiger Milk Mushroom, Lignosus rhinocerus FOOD TECHNOLOGY AND BIOTECHNOLOGY | 2022
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The Prevalence and Associated Risk Factors of Carpal Tunnel Syndrome among Private Dentists in Klang Valley, Malaysia: A Cross-sectional Study ANNALS OF DENTISTRY UNIVERSITY OF MALAYA | 2022
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In Vitro inhibition of melanin formation and enhancement of collagen production by a mushroom sclerotial water extract from the tiger milk mushroom, Lignosus rhinocerus (agaricomycetes), with No skin and eye irritation INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS | 2022
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Bioactive properties of Malaysian medicinal mushrooms Lignosus spp FUNGAL BIOTECHNOLOGY: PROSPECTS AND AVENUES. BOCA RATON (FL) | 2022
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Activation function 1 of progesterone receptor is required for mammary development and regulation of RANKL during pregnancy SCIENTIFIC REPORTS | 2022
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Volatile molecules secreted by the wheat pathogen Parastagonospora nodorum are involved in development and phytotoxicity FRONTIERS IN MICROBIOLOGY | 2020
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Immunomodulatory properties of water-soluble polysaccharides extracted from the fruiting body of Chinese caterpillar mushroom, Ophiocordyceps sinensis cultivar OCS02®(Ascomycetes) INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS | 2020
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The immunomodulating properties of tiger milk medicinal mushroom, Lignosus rhinocerus TM02® cultivar (Agaricomycetes) and its associated carbohydrate composition INTERNATIONAL JOURNAL OF MEDICINAL MUSHROOMS | 2020
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Computer-Assisted Learning vs. Small Group Tutorials in Periodontal Charting: A Randomized Controlled Trial in a Malaysian Dental School JOURNAL OF OROFACIAL SCIENCES | 2019
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Inhibition of protein glycation by tiger milk mushroom [Lignosus rhinocerus (Cooke) Ryvarden] and search for potential anti-diabetic activity-related metabolic pathways by genomic and transcriptomic data mining FRONTIERS IN PHARMACOLOGY | 2018
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Molecular attributes and apoptosis-inducing activities of a putative serine protease isolated from Tiger Milk mushroom (Lignosus rhinocerus) sclerotium against breast cancer cells in vitro PEERJ | 2018
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Heterologous expression of cytotoxic sesquiterpenoids from the medicinal mushroom Lignosus rhinocerotis in yeast MICROBIAL CELL FACTORIES | 2017
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The Genome, Transcriptome, and Proteome Analyses of Lignosus Rhinocerotis (Cooke) Ryvarden (Tiger Milk Mushroom) and Its Potential Medicinal Properties N/A | 2015
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Transcriptome analysis revealed highly expressed genes encoding secondary metabolite pathways and small cysteine-rich proteins in the sclerotium of Lignosus rhinocerotis PLOS ONE | 2015
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Genome-based proteomic analysis of Lignosus rhinocerotis (Cooke) Ryvarden sclerotium INTERNATIONAL JOURNAL OF MEDICAL SCIENCES | 2015
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Shotgun proteomic analysis of tiger milk mushroom (Lignosus rhinocerotis) and the isolation of a cytotoxic fungal serine protease from its sclerotium JOURNAL OF ETHNOPHARMACOLOGY | 2015
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Nutrient composition, antioxidant properties, and anti‐proliferative activity of Lignosus rhinocerus Cooke sclerotium JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE | 2015
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Energy and nutritional composition of Tiger Milk Mushroom (Lignosus tigris Chon S. Tan) sclerotia and the antioxidant activity of its extracts INTERNATIONAL JOURNAL OF MEDICAL SCIENCES | 2014
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DNA barcode markers for two new species of Tiger Milk Mushroom: Lignosus tigris and L. cameronensis INTERNATIONAL JOURNAL OF AGRICULTURE AND BIOLOGY | 2014
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The genome of the Tiger Milk mushroom, Lignosus rhinocerotis, provides insights into the genetic basis of its medicinal properties BMC GENOMICS | 2014
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Nutrient composition, antioxidant properties, and anti‐proliferative activity of Lignosus rhinocerus Cooke sclerotium JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE | 2013
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Breathing new life to a Malaysia lost national treasure-the Tiger-Milk mushroom (Lignosus rhinocerotis) MUSHROOM SCIENCE XVIII: PROCEEDINGS OF THE18TH CONGRESS OF THE INTERNATIONAL SOCIETY FOR MUSHROOM SCIENCE | 2012
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Resistance against tumour necrosis factor α apoptosis by the cellular prion protein is cell‐specific for oral, colon and kidney cancer cell lines CELL BIOLOGY INTERNATIONAL | 2012
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Isolation and characterization of the thrombin-like enzyme from Cryptelytrops albolabris (white-lipped tree viper) venom COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY PART B: BIOCHEMISTRY AND MOLECULAR BIOLOGY | 2012
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Resistance against apoptosis by the cellular prion protein is dependent on its glycosylation status in oral HSC-2 and colon LS 174T cancer cells CANCER LETTERS | 2011
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Evaluation of the anti-apoptotic property of cellular prion protien in kidney, oral and colon cancer cell lines N/A | 2011

Other Publications

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Wound Healing Potential of Lignosus rhinocerus TM02®: Genomic Insights Asian Regional Conference on Systems Biology 2023 | 21 Dec 2023
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In vitro antibacterial screening of Lignosus rhinocerus TM02® (Tiger Milk Mushroom) extracts The 46th Annual Conference of the Malaysian Society for Biochemistry and Molecular Biology | 24 Aug 2022
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Apoptosis induction and immunomodulation in a human oral cancer cell line, ORL 204 by Lignosus rhinocerus TM02 ® via a proposed intervention of TNF signaling MAHSA International Dentistry Conference 2022 | 24 Jun 2022
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Polycystic Ovary Syndrome (POCS) and Periodontitis: A Blibliometric Analysis MAHSA International Dentistry Conference 2021 | 24 Sep 2021
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Anti-Cancer Property of Tiger Milk Mushroom in Selected Oral Cancer Cell Lines, 27th FAOBMB & 44th MSBMB Conference 27th FAOBMB & 44th MSBMB Conference | 19 Aug 2019
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The Immunomodulation Property of Tiger Milk Mushroom and Its Cytotoxic Effect in Selected Oral Cancer Cell Lines MAHSA Research Carnival | 22 Nov 2018
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Analysis of Functional Mutations of Activation Function 1 of Progesterone Receptor in Mice Basel Life, Congress Center Basel | 10 Sep 2017
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Insights into the Genome of Lignosus Rhinocerotis (Cooke) Ryvarden University of Malaya Researchers’ Conference (UMRC) 2013 | 19 Nov 2013
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Evaluation of Antioxidant Activity of Lignosus rhinocerus (Tiger milk mushroom) sclerotia The 18th Congress of the International Society for Mushroom Science | 26 Aug 2012
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Molecular Phylogeny of Lignosus rhinocerus (Tiger Milk Mushroom) Based on Complete 18S and 28S Ribosomal DNA Sequences The 18th Congress of the International Society for Mushroom Science | 26 Aug 2012
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Evaluation of the Antioxidant Activity in Lignosus spp 36th Annual Conference of the MSBMB | 27 Jul 2011
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Evaluation of the Proliferative and Anti-Apoptotic Properties of Cellular Prion Protein in Kidney, Oral and Colon Cancer Cell Lines 8th International Symposium of Health Sciences (i-SIHAT 2010) | 09 Dec 2010
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Site-Directed Mutagenesis and Stable Overexpression of Alpha-Synuclein Mutations of Familial Parkinson's Disease in neuronal cell lines 34th Annual Conference of the MSBMB | 07 Oct 2009

Books

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CRC Press (2022). Omics for Natural Products as Adjunct Nutrition

Patents

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LIGNOSUS RHINOCEROTIS SERINE PROTEASE | 27 Jan 2015
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MEDICINAL USE OF THE EXTRACT OF LIGNOSUS RHINOCEROTIS | 08 Apr 2013


Supervisions
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Ng Min Jia | Doctorate | 12 Nov 2019 Thesis: IN VIVO ANTITUMOUR PROSPECT OF LIGNOSUS RHINOCERUS COOKE RYVARDEN AND MULTI-OMICS STUDY OF LIGNOSUS TIGRIS C. S. TAN
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Yusra Mahdi | Master (Mixed Mode) | 20 Dec 2019 - 17 Nov 2020 Thesis: The antimicrobial activity of Swietenia macrophylla extract on plaque biofilm: An in-situ study
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Harveender Kaur | Master (Mixed Mode) | 02 Dec 2020 - 18 Nov 2021 Thesis: A Comparative Evaluation of Polymerization Shrinkage, Degree of Conversion, and Antibacterial Activity of Zirconia-Reinforced Rice Husk Nanohybrid Composite
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Yeu Kai Zhe | Master (Mixed Mode) | 06 Dec 2022 - 20 Oct 2023 Thesis: The Effects of Blue Diode Laser 450nm and Red Diode Laser 650nm on Dentinal Surface: A Comparative In Vitro Study
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Tan Kah Look, Lim Yin Ying | Undergraduate | 16 Nov 2018 - 01 Jun 2020 Thesis: In vitro cytotoxic and COX-2 inhibitory evaluation of tiger milk mushroom (Lignosus rhinocerus TM02) against a panel of human oral cancer cell lines
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Sheryl Teo Jing Ning, Wan Nurul Hana binti Wan Mohamad Saleh | Undergraduate | 23 Nov 2018 - 28 Jun 2020 Thesis: Prevalence of Carpal Tunnel Syndrome Among Dentists in Klang Valley
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Chan Zheng Wen, Ooi Pei Yun, Phuan Yi Fan | Undergraduate | 26 Nov 2019 - 22 Aug 2021 Thesis: An Assessment of Oral Cancer Knowledge, Attitudes, and Practices Among Undergraduate Students in Malaysian Dental Schools
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Aiman Muhamad Zulkiffili, Luqman Hakim Roslan, Nurul Husna Ilyana Azrin | Undergraduate | 01 Feb 2021 - 21 Jul 2022 Thesis: Assessment of Self-Perceived Malocclusion and Barriers to Orthodontic Treatment: A Cross-Sectional Study
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Asha Sharma Pusnaa a/p S Narayanan, Tan Pei Ying, Tay Kit Ken | Undergraduate | 25 Nov 2021 - 17 May 2023 Thesis: Efficacy of Strawberry Juice, Pineapple Juice, and Honey Solution in Counteracting Extrinsic Teeth Staining by Coffee: An In Vitro Study
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Aliza Nur Shuhaili binti Azlan, Ellysa Leong Teng Shan, Janet Chai Pei Shan | Undergraduate | 04 Oct 2022 Thesis: A Clinical Investigation into the Dermal Application of L. rhinocerus TM02 Water Extract for Mouth Ulceration