LIM LAY CHENG



Salutation
Dr

School/Centre
School of Pharmacy

Department
Life Sciences

Position
Senior Lecturer




Education

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PhD (Molecular Medicine), 2015 UKM Medical Molecular Biology Institute (UMBI)
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Master (Medical Science (Biochemistry)), 2007 Universiti Kebangsaan Malaysia
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BSc (Molecular Biology, Honours (Biochemistry)), 2004 Universiti Kebangsaan Malaysia

Memberships

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Malaysian Proteomics Society (MAPS) | National | Co-Opted Committee Member
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Persatuan Alumni UKM Medical Molecular Biology Institute | National | Vice-President (2020 - 2022), Committee (2023 - Present)

Publications

Research Articles

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Single‐cell proteomics by mass spectrometry: Advances and implications in cancer research PROTEOMICS | 2024
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EtOH-LN cryoembedding workflow to minimize freezing artifact in frozen tissues: A pilot study in preparing tissues compatible with mass spectrometry-based spatial proteomics application CRYOBIOLOGY | 2023
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Molecular tissue profiling by MALDI imaging: recent progress and applications in cancer research Critical Reviews in Clinical Laboratory Sciences | 2021
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Perspectives and advancements in the design of nanomaterials for targeted cancer theranostics Chemico-biological interactions | 2020
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Gene therapy and type 1 diabetes mellitus Biomedicine & Pharmacotherapy | 2018
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Proteome heterogeneity in colorectal cancer Proteomics | 2018
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Identification of differentially expressed proteins in the serum of colorectal cancer patients using 2D-DIGE proteomics analysis Pathology & Oncology Research | 2016

Other Publications

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Spatial Proteome Mapping of Annotated Tumour Regions in Pancreatic Ductal Adenocarcinoma Tissues Reveals Eight Distinct Tumour Subpopulations HUPO 2023 Congress | 17 Sep 2023
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SPATIAL PROTEOME PROFILING OF DISTINCT CANCER CELL SUBPOPULATIONS WITHIN PANCREATIC DUCTAL ADENOCARCINOMA (PDAC): A PILOT STUDY International Undergraduate Medical Research Conference (IUMRC) 2021 | 02 Nov 2021
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Expression and clinical significance of cytochrome c oxidase subunit Vib polypeptide 2 (COX6B2) and CKLF-like MARVEL transmembrane domain-containing protein 2 (CMTM2) in PDAC tumour 10th Asia-Oceania Human Proteome Organization Congress | 30 Jun 2021
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E f f e c t o f E d i b l e B i r d ’ s N e s t E x t r a c t on Cytokines Product ion in Human Immuni ty Choong 24th IUBMB Congress & 15th FAOBMB Congress (IUBMB Seoul 2018) | 04 Jun 2018
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Establishment of the modular immune in vitro construct (MIMIC) to evaluate the effect of edible bird’s nest on human immunity Universiti Tunku Abdul Rahman Inaugural FMHS Scientific Meeting 2017 | 25 May 2017
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Effect of edible-bird nest (EBN) on global gene and protein expression of Wharton’s Jelly. 3rd Edible Bird Nest Industry Conference (EBNIC) 2016: Empowering the essence of edible bird nest | 11 Oct 2016
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Cancer proteomics for biomarker discovery Centre for Cancer Research Monthly Seminar, University of Tunku Abdul Rahman | 18 May 2016
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Serum proteomics-based identification of differentially expressed proteins in colorectal cancer. 1st National Conference for Cancer Research & 5th Regional Conference on Molecular Medicine (RCMM) | 08 Nov 2013
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Serum proteomics-based identification of differentially expressed proteins in colorectal cancer Asia-Pacific Journal of Molecular Medicine | 01 Jan 2013
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Comparative serum proteomic and pathway analysis reveals potential candidate biomarkers in colorectal cancer 4th Regional Conference on Molecular Medicine 2011 | 09 Oct 2011
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Effect of age on erythrocyte antioxidant enzymes and plasma vitamin levels. Proceedings of the 14th biennial meeting of the Society for Free Radical Research International | 18 Oct 2008
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Effect of age on antioxidant status and oxidative stress markers among Malays in Klang Valley 6th Costam/SFRR (Asean/Malaysia) International Workshop, Kuching, Sarawak | 29 Jun 2006
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Age-related changes in antioxidant enzymes activities in subjects from Klang Valley and Terengganu populations Regional Conference on Molecular Medicine 2005 organized by UKM Medical Molecular Biology Institute (UMBI) | 09 Sep 2005
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The effect of age on catalase and superoxide dismutase enzymes activities among Malaysians 29th Annual Conference of the Malaysian Society for Biochemistry & Molecular Biology | 28 Sep 2004


Supervisions
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Goh Jin Pin | Undergraduate | 01 Feb 2019 - 30 Sep 2019 Thesis: Identification of cancer testis antigens (CTAs) in pancreatic cancer: The search for potential immunotherapeutic targets
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Naili Hanani | Undergraduate | 03 Feb 2020 - 31 Jul 2021 Thesis: Spatial proteome profiling of distinct cancer cell subpopulations within pancreatic ductal adenocarcinoma (PDAC): A pilot study
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Tan Yong Chiang | Doctorate | 01 Nov 2020 - 30 Apr 2024 Thesis: Spatial mapping and proteogenomic characterization of tumour subclones in pancreatic ductal adenocarcinoma
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Chong Yuen Ping | Master (Research) | 01 Jan 2019 - 01 Jan 2023 Thesis: The influence of pancreatic ductal adenocarcinoma (PDA) cells and pancreatic stellate cells (PSC) on myeloid derived suppressor cells (MDSC) immunosuppressive properties
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Alex Lee Wei Yan | Master (Coursework) | 01 Sep 2023 - 30 Jun 2024 Thesis: Membrane proteome profiling on metastatic pancreatic ductal adenocarcinoma (PDAC) cell lines
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Yoshana a/p Muruganand | Undergraduate | 01 Jan 2024 - 31 Oct 2024 Thesis: Membrane proteome profiling on primary pancreatic ductal adenocarcinoma (PDAC) cell lines